Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Leonard J. Schiff"'
Publikováno v:
Chemistry and Biology of Synthetic Retinoids ISBN: 9781351070638
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d440afb4dee4d81371ac9ddf86540c0
https://doi.org/10.1201/9781351070638-14
https://doi.org/10.1201/9781351070638-14
Autor:
C. T. Helmes, E. Meierhenry, Peter D. Hobbs, Marcia I. Dawson, Wan-Ru Chao, Leonard J. Schiff, Krzysztof Derdzinski, Rebecca L. S. Chan
Publikováno v:
Ciba Foundation Symposium 113-Retinoids, Differentiation and Disease
A series of conformationally restricted retinoids has been synthesized and assayed for biological activity. These compounds have aromatic rings in place of selected double bonds of the tetraene side-chain of retinoic acid and could be considered as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcc391860eb37bd5fb11e183d929b9f6
https://doi.org/10.1002/9780470720943.ch2
https://doi.org/10.1002/9780470720943.ch2
Autor:
Leonard J. Schiff, Gang Liu, Tomas Mustelin, Danni L. Harris, Brahma P. Sani, Jun-ichi Fukushi, Zebin Xia, Mao Ye, Peter D. Hobbs, Sankari Arumugarajah, Marcia I. Dawson, Wan-Ru Chao, William B. Stallcup, Xiao-kun Zhang, Ying Su, Nahid Waleh, Lulu Farhana, Lutz Tautz, Young-Hoon Han, Joseph A. Fontana, Bhamik B. Patel, Mohammad Bhuiyan, Ling Jong
Apoptotic and antiproliferative activities of small heterodimer partner (SHP) nuclear receptor ligand (E)-4-[3'-(1-adamantyl)-4'-hydroxyphenyl]-3-chlorocinnamic acid (3-Cl-AHPC), which was derived from 6-[3'-(1-adamantyl)-4'-hydroxyphenyl]-2-naphthal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07933b22a5efeceee356dbb6c7bcb108
https://europepmc.org/articles/PMC2528874/
https://europepmc.org/articles/PMC2528874/
Autor:
Leonard J. Schiff
Publikováno v:
In Vitro Cellular and Developmental Biology--Animal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fce16aae3d93c16e139468fca73c0663
https://doi.org/10.1290/0503024
https://doi.org/10.1290/0503024
Autor:
Leonard J. Schiff
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 41:65
A critical component in controlling the production of biological products derived from human and animal cell lines is the characterization and testing of banked cell substrates. The objective is to confirm the identity, purity, and suitability of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27610bbb3fbf35eb3f2aec5d2a4bffe4
https://doi.org/10.1290/0503024.1
https://doi.org/10.1290/0503024.1
Autor:
Rebecca L. S. Chan, Peter D. Hobbs, Wan Ru Chao, Krzysztof Derdzinski, Marcia I. Dawson, Leonard J. Schiff
Publikováno v:
Journal of Medicinal Chemistry. 26:1653-1656
6-[(E)-2-(2,6,6-Trimethyl-1-cyclohexen-1-yl)ethen-1-yl]- and 6-(1,2,3,4-tetrahydro-1,1,4,4-tetramethyl-6-naphthyl)-2-naphthalenecarboxylic acids (4 and 8) have been synthesized and show significant activity in reversing the keratinization process in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ca28eda8103b183f7541f31c5dc593a
https://doi.org/10.1021/jm00365a021
https://doi.org/10.1021/jm00365a021
Autor:
Leonard J. Schiff
Publikováno v:
In Vitro. 11:46-49
Human fibrin foam as a matrix for three-dimensional organ cultures was successfully employed for the cultivation of newborn rat and hamster colon tissue. Colonic tissue was maintained under different oxygen atmospheres and with various synthetic medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa83dd8b44bf006502bdcc4a8177f5e
https://doi.org/10.1007/bf02615321
https://doi.org/10.1007/bf02615321
Publikováno v:
Environmental Health Perspectives
The toxic effects of gas-phase singlet oxygen, /sup 1/O/sub 2/, on the ciliated respiratory epithelium of hamster trachea have been demonstrated. Tracheal explants treated with /sup 1/O/sub 2/ showed a dose-dependent decrease in cilia beating frequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7265e487a8f69f00c1120e956153b71b
https://doi.org/10.1289/ehp.8776199
https://doi.org/10.1289/ehp.8776199
Publikováno v:
Environmental Research. 19:339-354
Hamster tracheal tissue was used to study the effects of H 2 SO 4 mist, carbon particles, and mixtures of the two on cilia beating frequency and morphological alterations of respiratory epithelium. Hamsters were exposed for 3 hr to 1.1 mg/m 3 H 2 SO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e533352391b59f6bd5fe57e8d326933a
https://doi.org/10.1016/0013-9351(79)90060-4
https://doi.org/10.1016/0013-9351(79)90060-4
Publikováno v:
Environmental Research. 41:514-528
Various health effect parameters were compared to determine which tests were the most sensitive indicators of toxic effects of exposure to metallic sulfate aerosols. Inhalation studies were conducted involving either single 3-hr exposure to various c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752175b050095a45556c77b17d48e5cd
https://doi.org/10.1016/s0013-9351(86)80146-3
https://doi.org/10.1016/s0013-9351(86)80146-3