Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Leonard J. Czuba"'
2
Structure-activity relationships in a series of novel 3,4-dihydro-4-oxopyrimido[4,5-b]quinoline-2-carboxylic acid antiallergy agents
Autor: Leonard J. Czuba, P. F. Moore, T. H. Althuis, S. B. Kadin, H.-J. Hess
Publikováno v: Journal of Medicinal Chemistry. 23:262-269
A series of more than 50 new 3,4-dihydro-4-oxopyrimido[4,5-b]quinoline-2-carboxylic acid derivatives and related compounds with substituent variations at the 2, 3, and 5--9 positions was prepared and evaluated for antiallergy activity using the rat P
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c8ec165e1f5fd6b8e96e2b08bfcd00
https://doi.org/10.1021/jm00177a010
Zobrazit plný text záznamu
6
ChemInform Abstract: STRUCTURE-ACTIVITY RELATIONSHIPS IN A SERIES OF NOVEL 3,4-DIHYDRO-4-OXOPYRIMIDO(4,5-B)QUINOLINE-2-CARBOXYLIC ACID ANTIALLERGY AGENTS
Autor: H.-J. Hess, Leonard J. Czuba, P. F. Moore, S. B. Kadin, T. H. Althuis
Publikováno v: Chemischer Informationsdienst. 11
A series of more than 50 new 3,4-dihydro-4-oxopyrimido[4,5-b]quinoline-2-carboxylic acid derivatives and related compounds with substituent variations at the 2, 3, and 5--9 positions was prepared and evaluated for antiallergy activity using the rat P
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ff82452771d537e22444f44df4b827ab
https://doi.org/10.1002/chin.198033244
Zobrazit plný text záznamu
7
ChemInform Abstract: SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF 1-HYDROXY-1-METHYL-1,3-DIHYDROFURO(3,4-B)QUINOXALINE 4,9-DIOXIDE AND RELATED COMPOUNDS
Autor: B. W. Dominy, Richard B. James, Wendell W. Windisch, John P. Dirlam, Leonard J. Czuba, Joseph E. Presslitz, Richard M. Pezzullo
Publikováno v: Chemischer Informationsdienst. 11
A Free-Wilson analysis of the antibacterial activity found in a variety of quinoxaline 1,4-dioxides prepared and tested in these laboratories unexpectedly predicted that potent activity should be found in the case where the heterocyclic ring system w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fbfc0f72e62f147362917a5c4f8b1696
https://doi.org/10.1002/chin.198005284
Zobrazit plný text záznamu
8
Chapter 8. Antithrombotic Agents
Autor: Leonard J. Czuba
Publisher Summary This chapter describes the development and clinical studies of antithrombotic agents. The therapeutic approaches to the treatment of thrombosis include inhibition of platelet aggregation, inhibition of blood coagulation, and enhance
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b144499e4b918ef7cce55b9b5d9d6b90
https://doi.org/10.1016/s0065-7743(08)60803-9
Zobrazit plný text záznamu
9
Chapter 7. Platelet Aggregation Inhibitors
Autor: Leonard J. Czuba
Publisher Summary This chapter presents an overview of the platelet aggregation inhibitors. The therapeutic approach to thromboembolic disease is based on the inhibition of platelet aggregation. The use of fibrinolytic agents for the dissolution of t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6547dc275308e7a0297018e2a4acb7e6
https://doi.org/10.1016/s0065-7743(08)60962-8
Zobrazit plný text záznamu
10
A practical synthesis of pyoluteorin
Autor: Wendell W. Windisch, Berkeley W. Cue, John P. Dirlam, Leonard J. Czuba
Publikováno v: Journal of Heterocyclic Chemistry. 18:191-192
A convenient, large-scale synthesis of the antibiotic pyoluteorin, 2,3-dichloro-5-(2′,6′-dihydroxybenzoyl)-pyrrole (1), is described. A key step in the synthesis involved a Friedel-Crafts aroylation of pyrrole with 2,6-dimethoxybenzoyl chloride (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9a06d63dc6fe63e89c535a8ecae4087e
https://doi.org/10.1002/jhet.5570180136
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje