Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Leonard J, Giblin"'
1
Free zinc ions outside a narrow concentration range are toxic to a variety of cells in vitro
Autor: Leonard J. Giblin, Christopher J. Frederickson, Irina Korichneva, Richard B. Thompson, Sarah Libert, Rebecca A. Bozym, Fabrice Chimienti, Maryam Parviz, Wolfgang Maret, Yuan Li, Gunter W Gross
Publikováno v: Experimental Biology and Medicine. 235:741-750
The zinc(II) ion has recently been implicated in a number of novel functions and pathologies in loci as diverse as the brain, retina, small intestine, prostate, heart, pancreas, and immune system. Zinc ions are a required nutrient but elevated concen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1dbdaea358d4714456d1ecba3bd48b
https://doi.org/10.1258/ebm.2010.009258
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2
Zinc-secreting Paneth Cells Studied by ZP Fluorescence
Autor: Anthony F. Bentley, Cathleen J. Frederickson, Stephen J. Lippard, Christopher J. Chang, Leonard J. Giblin, Christopher J. Frederickson
Publikováno v: Journal of Histochemistry & Cytochemistry. 54:311-316
We have used a new family of zinc-specific-responsive fluorescent dyes (ZPs) to study the sequestration and secretion of zinc from Paneth cells, which are located in the bases of the crypts of Lieberkühn within the rat small intestine. Vivid ZP fluo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba5cc3c8433d4cdde90d209d7284ad98
https://doi.org/10.1369/jhc.5a6724.2005
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3
Evidence That the ZNT3 Protein Controls the Total Amount of Elemental Zinc in Synaptic Vesicles
Autor: Leonard J. Giblin, David H. Linkous, Jane M. Flinn, Antonio Lanzirotti, Christopher J. Frederickson, Paul M. Bertsch, Jae Y. Koh, Blair F. Jones
The ZNT3 protein decorates the presynaptic vesicles of central neurons harboring vesicular zinc, and deletion of this protein removes staining for zinc. However, it has been unclear whether only histochemically reactive zinc is lacking or if, indeed,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb94f5c285dd943a476f836d34e80b0
https://europepmc.org/articles/PMC2323120/
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4
Meeting Report: Zinc Signals 2007—Expanding Roles of the Free Zinc Ion in BiologyA Report on the 8th Annual Institute of Zinc In Biology: Zinc Signals Meeting, Cook’s Branch Ranch, Woodlands, Texas, June 1 to 4, 2007
Autor: Richard B. Thompson, Leonard J. Giblin, Christopher J. Frederickson, Harold Sandstead, Wolfgang Maret, Cathleen J. Frederickson
Publikováno v: Science's STKE. 2007
One hundred years after Camille Delezenne was nominated for the Nobel Prize for his work on zinc-secreting salivary and pancreatic cells, the Institute of Zinc in Biology sponsored its eighth annual Zinc Signals conference. Convened in a pristine nat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e03affc94f53bc8fde1c9ee98b2ac237
https://doi.org/10.1126/stke.4112007pe61
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5
Synaptic release of zinc from brain slices: factors governing release, imaging, and accurate calculation of concentration
Autor: Christopher J, Frederickson, Leonard J, Giblin, Rengarajan V, Balaji, Balaji, Rengarajan, Rafik, Masalha, Cathleen J, Frederickson, Yaping, Zeng, Emilio Varea, Lopez, Jae-Young, Koh, Udi, Chorin, Limor, Besser, Michal, Hershfinkel, Yang, Li, Richard B, Thompson, Artur, Krezel
Publikováno v: Journal of neuroscience methods. 154(1-2)
Cerebrocortical neurons that store and release zinc synaptically are widely recognized as critical in maintenance of cortical excitability and in certain forms of brain injury and disease. Through the last 20 years, this synaptic release has been obs
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f8782b2ddc56e9fe4f3b85cfd89a492
https://pubmed.ncbi.nlm.nih.gov/16460810
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6
The Gluzinergic Synapse: Who’s Talking and Who’s Listening?
Autor: Leonard J. Giblin, Christopher J. Frederickson, Michal Hershfinkel
Publikováno v: Synaptic Plasticity and Transsynaptic Signaling ISBN: 9780387240084
It is now almost half a century since Maske (1955) discovered the bright red band of zinc:dithizone staining in the brain that marks the gluzinergic synapses in stratum lucidum of the hippocampal formation. These 50 years have witnessed a dramatic, n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7ea737e6ea3e9949385adf02c8c3b629
https://doi.org/10.1007/0-387-25443-9_9
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7
Sensitive and selective detection of zinc ions in neuronal vesicles using PYDPY1, a simple turn-on dipyrrin
Autor: Paul A. Bentley, Yuliya V. Medvedeva, John H. Weiss, Christopher J. Frederickson, Leonard J. Giblin, Yujiang Mei
Publikováno v: Chemical Communications. 47:7107
A new class of in vitro Zn(II) chemosensor based on dipyrrin has been developed. 5-(Pyren-1-yl)-4,6-dipyrrin (PYDPY1) was synthesized and exhibited high selectivity and sensitivity to Zn(II) (K(d) of 20 μM) compared to other metal ions. PYDPY1 was a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b41f1610532700a406c0c8c7d47bd51
https://doi.org/10.1039/c1cc12181b
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