Zobrazeno 1 - 10
of 205
pro vyhledávání: '"Leonard H. Augenlicht"'
Autor:
Jiahn Choi, Leonard H. Augenlicht
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 3, Pp 495-500 (2024)
Abstract The intestinal epithelium is the first line of defense and acts as an interface between the vast microbial world within the gastrointestinal tract and the body’s internal milieu. The intestinal epithelium not only facilitates nutrient abso
Externí odkaz:
https://doaj.org/article/b24729831d10475d90d99cf0e6e3abf4
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Notch signaling determines cell fates in mouse intestine. Notch receptors contain multiple epidermal growth factor-like (EGF) repeats modified by O-glycans that regulate Notch signaling. Conditional deletion of protein O-fucosyltransferase 1
Externí odkaz:
https://doaj.org/article/d8906cd5bdb240128fc613928d1be229
Autor:
Ross S. Firestone, Mu Feng, Indranil Basu, Karina Peregrina, Leonard H. Augenlicht, Vern L. Schramm
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract A mouse model of human Familial Adenomatous Polyposis responds favorably to pharmacological inhibition of 5′-methylthioadenosine phosphorylase (MTAP). Methylthio-DADMe-Immucillin-A (MTDIA) is an orally available, transition state analogue
Externí odkaz:
https://doaj.org/article/635250f8ffb640bcabea407fc2831f58
Publikováno v:
International Journal of Cell Biology, Vol 2011 (2011)
Heterogeneity among cells that constitute a solid tumor is important in determining disease progression. Our previous work established that, within a population of metastatic colonic tumor cells, there are minor subpopulations of cells with stable di
Externí odkaz:
https://doaj.org/article/e50b03c175814141bea6213e45d588c0
The short-chain fatty acid sodium butyrate (NaB), produced in the colonic lumen, induces cell cycle arrest, differentiation, and/or apoptosis in colorectal carcinoma cells in vitro, establishing a potential role for NaB in colon cancer prevention. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ab14742cff8f3f3b38034257ef7cc3
https://doi.org/10.1158/1940-6207.c.6544274
https://doi.org/10.1158/1940-6207.c.6544274
Supplementary Figure 1 from Transcriptional Attenuation in Colon Carcinoma Cells in Response to Butyrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::223375e59d73603560aa351f028bb3d9
https://doi.org/10.1158/1940-6207.22524488
https://doi.org/10.1158/1940-6207.22524488
Supplementary Figure 2 cont. from Transcriptional Attenuation in Colon Carcinoma Cells in Response to Butyrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79357f0c076e8c12a2fca63a61071394
https://doi.org/10.1158/1940-6207.22524485.v1
https://doi.org/10.1158/1940-6207.22524485.v1
Autor:
Christos S. Mantzoros, John P. Chamberland, Gil Atzmon, John J. Lofrese, Xueying Zhang, Leonard H. Augenlicht, Derek M. Huffman
Perspective on This Article from Abdominal Obesity, Independent from Caloric Intake, Accounts for the Development of Intestinal Tumors in Apc1638N/+ Female Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8367391b58fb82ba340f070de899ad5d
https://doi.org/10.1158/1940-6207.22524968
https://doi.org/10.1158/1940-6207.22524968
Supplementary Table 2 from Transcriptional Attenuation in Colon Carcinoma Cells in Response to Butyrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d02459deadffdff675312ad579175dc
https://doi.org/10.1158/1940-6207.22524476.v1
https://doi.org/10.1158/1940-6207.22524476.v1
Autor:
Christos S. Mantzoros, John P. Chamberland, Gil Atzmon, John J. Lofrese, Xueying Zhang, Leonard H. Augenlicht, Derek M. Huffman
To determine whether visceral fat (VF), independent of other confounders, is causally linked to intestinal tumorigenesis, we surgically removed visceral fat in Apc1638/N+ mice. At 15 weeks of age, male and female Apc1638/N+ mice were randomized to on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::663ba81fca6c9cebe84a7b9943b0e3b4
https://doi.org/10.1158/1940-6207.c.6544508
https://doi.org/10.1158/1940-6207.c.6544508