Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Leonard Chuck"'
Publikováno v:
Contemporary Clinical Trials Communications, Vol 35, Iss , Pp 101200- (2023)
eConsent is an electronic informed consent experience that contains videos, word flags, and knowledge checks, in addition to an electronic version of the informed consent document to enhance clinical trial participants’ understanding of what they a
Externí odkaz:
https://doaj.org/article/6c988217880645268e83e070298ddcad
Autor:
George Capuano, Jagriti Craig, Leonard Chuck, Julio Rosenstock, Manuel González-Ortiz, Kate Merton, Rong Qiu
Publikováno v:
Diabetes Care. 39:353-362
OBJECTIVE This study assessed the efficacy/safety of canagliflozin (CANA), a sodium–glucose cotransporter 2 (SGLT2) inhibitor, plus metformin extended-release (MET) initial therapy in drug-naïve type 2 diabetes. RESEARCH DESIGN AND METHODS This 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353162ad1fac33f16bacfec07c99df5b
https://doi.org/10.2337/dc15-1736
https://doi.org/10.2337/dc15-1736
Publikováno v:
Cardiovascular Research. 8:243-248
The effects of phentolamine and noradrenaline on force development of isolated papillary muscles and on the adenyl cyclase activity of the ventricular myocardium were studied in cats. Phentolamine alone did not influence either force or adenyl cyclas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c7eccb9d3d9d3f847dacc2d8393c6f5
https://doi.org/10.1093/cvr/8.2.243
https://doi.org/10.1093/cvr/8.2.243
Publikováno v:
The American Journal of Cardiology. 32:889-894
This study was designed to quantitate the length-tension relations of surgically resected human ventricular aneurysms in order to calculate the degree of paradoxical systolic expansion and mechanical disadvantage produced by various types of aneurysm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::697d747b3223662e141bae8db58831e5
https://doi.org/10.1016/s0002-9149(73)80153-5
https://doi.org/10.1016/s0002-9149(73)80153-5
Autor:
Jean Lucien Rouleau, William W. Parmley, Bruce H. Brundage, Leonard Chuck, Stanley A. Rubin, Thomas A. Ports, Roger L. Williams, Kanu Chatterjee, Stephen B. Arnold
Publikováno v:
American Heart Journal. 102:622-625
Three series of investigations were carried out with prazosin (PZN) hydrochloride. In the first, hemodynamic effects of PZN were compared with those of hydralazine (HDZ) in 11 patients with chronic congestive heart failure (CHF). In doses up to 5 mg,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ced0aa63d742c8393bd89f593ad3cc
https://doi.org/10.1016/0002-8703(81)90754-7
https://doi.org/10.1016/0002-8703(81)90754-7
Autor:
Helge Refsum, William W. Parmley, Richard E. Sievers, Jean-Lucien Rouleau, Leonard Chuck, Detlef Mathey
Publikováno v:
American heart journal. 108(1)
We studied 56 right ventricular papillary muscles isolated from cats to determine whether the direct mechanical effects of contrast media are due to their pharmacologic action or to the hyperosmolality caused by them. A 10% solution of Renografin-76
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5f4b5e003041d7a58480fbef8053486
https://pubmed.ncbi.nlm.nih.gov/6428210
https://pubmed.ncbi.nlm.nih.gov/6428210
Publikováno v:
Journal of cardiovascular pharmacology. 4(4)
We investigated the hemodynamic and inotropic effects of the new class III antiarrhythmic drug melperone. In eight pentobarbital-anesthetized dogs, the effects of intravenous melperone 0.5, 2.5, and 12.5 mg/kg-1 were tested. During atrial pacing we m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6fba5882920f81d6058f4d89d2c6b59
https://pubmed.ncbi.nlm.nih.gov/6181340
https://pubmed.ncbi.nlm.nih.gov/6181340
Publikováno v:
The Journal of clinical pharmacology and new drugs. 12(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::765705e349633d654e491e6badc12edc
https://pubmed.ncbi.nlm.nih.gov/4401703
https://pubmed.ncbi.nlm.nih.gov/4401703
Publikováno v:
Japanese circulation journal. 36(5)
The direct myocardial depressant effects of lidocaine, ajmalin, propranolol and quinidine were determined in vitro in isolated right ventricular papillary muscles and spontaneously beating right atria of the cat. In concentrations similar to therapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a1f97e069aa215483567c3b1b6af3a
https://pubmed.ncbi.nlm.nih.gov/5068725
https://pubmed.ncbi.nlm.nih.gov/5068725
Publikováno v:
Circulation research. 30(1)
The present study was undertaken to reevaluate the effects of preload on maximum velocity of shortening at zero load, V max , relative to the length-tension curve. Force-velocity relations were measured from afterloaded isotonic contractions and were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::289a2d1935bb40b453c8091bb8e73d16
https://pubmed.ncbi.nlm.nih.gov/5007526
https://pubmed.ncbi.nlm.nih.gov/5007526