Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Leonard C Archard"'
Autor:
Yanwen Li, Leonard C. Archard, Michael J. Dunn, Hongyi Zhang, Najma Latif, Peter J. Richardson, Dougal R. McClean, Mary N. Sheppard, Karen Morrison, Richard Florio
Publikováno v:
Medical Microbiology and Immunology. 193:109-114
The association of enteroviruses with myocardial disease has been investigated extensively by molecular biological techniques to detect viral RNA, but remains controversial. This retrospective study investigated the involvement of enterovirus in myoc
Publikováno v:
Cardiovascular Research. 50:46-55
Objective: The mechanisms by which Coxsackie B viruses cause myocarditis or dilated cardiomyopathy are not well understood. This study examined changes in the expression of cardiac genes resulting from Coxsackievirus B3 (CVB3) infection of mice. Meth
Publikováno v:
Journal of Medical Virology. 64:175-182
Increased expression of inducible nitric oxide synthase (iNOS) has been found in inflammatory myocardial disease and increased production of nitric oxide (NO) has both an inhibitory effect on virus replication and a cytotoxic effect on host cells. To
Autor:
Yingzhen Yang, Tianqing Peng, Leonard C. Archard, Yanwen Li, Li Zhang, Hongyi Zhang, Malen Aasa
Publikováno v:
Journal of Histochemistry & Cytochemistry. 48:579-584
SUMMARY The association of enterovirus infection and heart muscle diseases has been investigated extensively by detection of viral genomic RNA using nucleic acid hybridization and the reverse transcription-polymerase chain reaction. To further unders
Publikováno v:
Clinical Immunology. 91:90-98
Coxsackie virus B3 (CVB3) infection results in a marked inflammatory response and the production of autoantibodies to cardiac antigens, with cardiac myosin heavy chain documented to be the most immunogenic antigen. The present study investigated the
Autor:
Michael J. Dunn, Leonard C. Archard, Colin H. Wheeler, Joseph M. Corbett, Peter J. Richardson, Magdi H. Yacoub, H. J. F. Why
Publikováno v:
Electrophoresis. 19:2031-2042
The aim of the investigation was to determine whether there are specific global quantitative and qualitative changes in protein expression in heart tissue from patients with dilated cardiomyopathy (DCM) compared with ischaemic heart disease and undis
Autor:
Howard J.F. Why, Hongyi Zhang, Mahboob A. Khan, Peter J. Richardson, Nicholas M.K. Robinson, Bambos A. Soteriou, Leonard C. Archard
Publikováno v:
Human Pathology. 29:578-584
This study was performed to detect and characterize the enterovirus present in myocardium of some patients with heart muscle disease by nucleotide sequencing of polymerase chain reaction (PCR) products after amplification with enterovirus group-speci
Publikováno v:
Journal of Virological Methods. 69:7-17
SWR mice develop viral myocarditis histologically similar to the human disease following inoculation with a cardiovirulent Coxsackievirus B3 (CVB3), reactivated from a sequenced cDNA clone of Nancy strain. A sequence of 215 nucleotides, or 628 nucleo
Publikováno v:
Archives of Virology. 140:959-966
We previously described a large plaque attenuant (p14V-1) derived from a cardiovirulent Coxsackievirus B3 (CVB3) and showed that there were no major determinants of either attenuation or plaque phenotype in the 5' nontranslated region (5'NTR). Part o
Publikováno v:
Clinical and Diagnostic Virology. 3:233-245
Background A majority of cases of viral myocarditis are associated with group B Coxsackieviruses (CVB) and the persistence of these viruses in the myocardium is associated with the progression of acute myocarditis to chronic dilated cardiomyopathy. A