Zobrazeno 1 - 10
of 445
pro vyhledávání: '"Leonard C, Harrison"'
Autor:
Andrew Baldi, Sabine Braat, Mohammed Imrul Hasan, Cavan Bennett, Marilou Barrios, Naomi Jones, Gemma Moir-Meyer, Imadh Abdul Azeez, Stephen Wilcox, Mohammad Saiful Alam Bhuiyan, Ricardo Ataide, Danielle Clucas, Leonard C. Harrison, Shams El Arifeen, Rory Bowden, Beverley-Ann Biggs, Aaron Jex, Sant-Rayn Pasricha
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Antibiotics may alter the gut microbiome, and this is one of the mechanisms by which antimicrobial resistance may be promoted. Suboptimal antimicrobial stewardship in Asia has been linked to antimicrobial resistance. We aim to examine the re
Externí odkaz:
https://doaj.org/article/78dba4e80bf8401c952644d67ed85a89
Autor:
Leonard C. Harrison, Natalie L. Stone, Esther Bandala-Sanchez, Nicholas D. Huntington, Robert I. McLachlan, Jai Rautela, Moira K. O’Bryan
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Seminal fluid provides for the carriage and nutrition of sperm, but also modulates immunity to prevent allo-rejection of sperm by the female. Immune suppression by seminal fluid has been associated with extracellular vesicles, originally termed prost
Externí odkaz:
https://doaj.org/article/9120c54a2cd3456db566a86693f05b9b
Autor:
William Rawlinson, Jason A Tye-Din, Simon Barry, Peter J Vuillermin, Leonard C Harrison, Georgia Soldatos, Maria E Craig, Elizabeth A Davis, Peter G Colman, Amanda Anderson, Emma Hamilton-Williams, Pat Ashwood, Tony Huynh, Rebecca L Thomson, Helena Oakey, Aveni Haynes, John M Wentworth, Bek Brittain, James D Brown, Dao Huynh, Ki-Wook Kim, Kelly J McGorm, Grant Morahan, Richard O Sinnott, Megan A S Penno, Jennifer J Couper
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 12, Iss 4 (2024)
Introduction The Environmental Determinants of Islet Autoimmunity (ENDIA) Study is an ongoing Australian prospective cohort study investigating how modifiable prenatal and early-life exposures drive the development of islet autoimmunity and type 1 di
Externí odkaz:
https://doaj.org/article/6bea03044ba743979e6137da76e170a8
Autor:
Leonard C Harrison, Esther Bandala‐Sanchez, Helena Oakey, Peter G Colman, Kelly Watson, Ki Wook Kim, Roy Wu, Emma E Hamilton‐Williams, Natalie L Stone, Aveni Haynes, Rebecca L Thomson, Peter J Vuillermin, Georgia Soldatos, William D Rawlinson, Kelly J McGorm, Grant Morahan, Simon C Barry, Richard O Sinnott, John M Wentworth, Jennifer J Couper, Megan AS Penno, the ENDIA Study Group
Publikováno v:
Journal of Diabetes Investigation, Vol 14, Iss 9, Pp 1092-1100 (2023)
ABSTRACT Aims/Introduction Autoantibodies to pancreatic islet antigens identify young children at high risk of type 1 diabetes. On a background of genetic susceptibility, islet autoimmunity is thought to be driven by environmental factors, of which e
Externí odkaz:
https://doaj.org/article/993f04912a044005ba462f8d64f9e9e5
Autor:
Helena Oakey, Lynne C. Giles, Rebecca L. Thomson, Kim-Anh Lê Cao, Pat Ashwood, James D. Brown, Emma J. Knight, Simon C. Barry, Maria E. Craig, Peter G. Colman, Elizabeth A. Davis, Emma E. Hamilton-Williams, Leonard C. Harrison, Aveni Haynes, Ki Wook Kim, Kylie-Ann Mallitt, Kelly McGorm, Grant Morahan, William D. Rawlinson, Richard O. Sinnott, Georgia Soldatos, John M. Wentworth, Jennifer J. Couper, Megan A. S. Penno
Publikováno v:
Annals of Medicine, Vol 55, Iss 1 (2023)
AbstractBackground: The Environmental Determinants of Islet Autoimmunity (ENDIA) pregnancy-birth cohort investigates the developmental origins of type 1 diabetes (T1D), with recruitment between 2013 and 2019. ENDIA is the first study in the world wit
Externí odkaz:
https://doaj.org/article/4020f54528be4126a735e523a39a8616
Autor:
Kirstine J. Bell, Sonia Saad, Bree J. Tillett, Helen M. McGuire, Sara Bordbar, Yu Anne Yap, Long T. Nguyen, Marc R. Wilkins, Susan Corley, Shannon Brodie, Sussan Duong, Courtney J. Wright, Stephen Twigg, Barbara Fazekas de St Groth, Leonard C. Harrison, Charles R. Mackay, Esteban N. Gurzov, Emma E. Hamilton-Williams, Eliana Mariño
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-21 (2022)
Abstract Background Short-chain fatty acids (SCFAs) produced by the gut microbiota have beneficial anti-inflammatory and gut homeostasis effects and prevent type 1 diabetes (T1D) in mice. Reduced SCFA production indicates a loss of beneficial bacteri
Externí odkaz:
https://doaj.org/article/e25eb74805594ff78c91c45cb9747d55
Autor:
Alexandra J. Roth-Schulze, Megan A. S. Penno, Katrina M. Ngui, Helena Oakey, Esther Bandala-Sanchez, Alannah D. Smith, Theo R. Allnutt, Rebecca L. Thomson, Peter J. Vuillermin, Maria E. Craig, William D. Rawlinson, Elizabeth A. Davis, Mark Harris, Georgia Soldatos, Peter G. Colman, John M. Wentworth, Aveni Haynes, Simon C. Barry, Richard O. Sinnott, Grant Morahan, Naiara G. Bediaga, Gordon K. Smyth, Anthony T. Papenfuss, Jennifer J. Couper, Leonard C. Harrison, on behalf of the ENDIA Study Group
Publikováno v:
Microbiome, Vol 9, Iss 1, Pp 1-21 (2021)
Abstract Background The gut microbiome changes in response to a range of environmental conditions, life events and disease states. Pregnancy is a natural life event that involves major physiological adaptation yet studies of the microbiome in pregnan
Externí odkaz:
https://doaj.org/article/253f5dc621044d0ea3730150c87cbbef
Autor:
Yuan Gao, Martin O’Hely, Thomas P. Quinn, Anne-Louise Ponsonby, Leonard C. Harrison, Hanne Frøkiær, Mimi L. K. Tang, Susanne Brix, Karsten Kristiansen, Dave Burgner, Richard Saffery, Sarath Ranganathan, Fiona Collier, Peter Vuillermin
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundPreclinical studies have shown that maternal gut microbiota during pregnancy play a key role in prenatal immune development but the relevance of these findings to humans is unknown. The aim of this prebirth cohort study was to investigate t
Externí odkaz:
https://doaj.org/article/630d6f836ed9453da3016197e9b393b9
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-14 (2021)
Abstract Background Except for bacteria, the taxonomic diversity of the human fecal metagenome has not been widely studied, despite the potential importance of viruses and eukaryotes. Widely used bioinformatic tools contain limited numbers of non-bac
Externí odkaz:
https://doaj.org/article/f21d67a3a9c84b3f820848d55be99484
Autor:
Sarah Hanieh, Siddhartha Mahanty, George Gurruwiwi, Therese Kearns, Roslyn Dhurrkay, Veronica Gondarra, Jenny Shield, Norbert Ryan, Francesca Azzato, Susan A. Ballard, Nicole Orlando, Sullen Nicholson, Katherine Gibney, Julie Brimblecombe, Wendy Page, Leonard C. Harrison, Beverley-Ann Biggs, on behalf of the Child Health and Nutrition Study team
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background To determine the prevalence of enteric infections in Aboriginal children aged 0–2 years using conventional and molecular diagnostic techniques and to explore associations between the presence of pathogens and child growth. Metho
Externí odkaz:
https://doaj.org/article/48953a1950b1495a8dff806264e9b759