Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Leonard B. Maggi Jr"'
Autor:
Vanessa Oliveira, Nitin Mahajan, Melissa L. Bates, Chakrapani Tripathi, Kyusik Q. Kim, Hani S. Zaher, Leonard B. Maggi Jr, Michael H. Tomasson
Publikováno v:
FASEB BioAdvances, Vol 1, Iss 7, Pp 404-414 (2019)
Abstract The orphan small nucleolar RNA (snoRNA) ACA11 is overexpressed as a result of the t(4;14) chromosomal translocation in multiple myeloma (MM), increases reactive oxygen species, and drives cell proliferation. Like other snoRNAs, ACA11 is pred
Externí odkaz:
https://doaj.org/article/2c20f4e656694a63b1229336ad7e548f
Autor:
Jason T. Forys, Catherine E. Kuzmicki, Anthony J. Saporita, Crystal L. Winkeler, Leonard B. Maggi, Jr., Jason D. Weber
Publikováno v:
Cell Reports, Vol 7, Iss 2, Pp 514-526 (2014)
Summary: The ARF and p53 tumor suppressors are thought to act in a linear pathway to prevent cellular transformation in response to various oncogenic signals. Here, we show that loss of p53 leads to an increase in ARF protein levels, which function t
Externí odkaz:
https://doaj.org/article/eaa17c2fcc3c482b9fcfd53d0e85ad7e
Autor:
Jing Qiu, Matteo Villa, David E. Sanin, Michael D. Buck, David O’Sullivan, Reagan Ching, Mai Matsushita, Katarzyna M. Grzes, Frances Winkler, Chih-Hao Chang, Jonathan D. Curtis, Ryan L. Kyle, Nikki Van Teijlingen Bakker, Mauro Corrado, Fabian Haessler, Francesca Alfei, Joy Edwards-Hicks, Leonard B. Maggi, Jr., Dietmar Zehn, Takeshi Egawa, Bertram Bengsch, Ramon I. Klein Geltink, Thomas Jenuwein, Edward J. Pearce, Erika L. Pearce
Publikováno v:
Cell Reports, Vol 27, Iss 7, Pp 2063-2074.e5 (2019)
Summary: Competition for nutrients like glucose can metabolically restrict T cells and contribute to their hyporesponsiveness during cancer. Metabolic adaptation to the surrounding microenvironment is therefore key for maintaining appropriate cell fu
Externí odkaz:
https://doaj.org/article/4ea68f59d3e14e4bbf5687d54711cf4f