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pro vyhledávání: '"Leonard B. Kirschner"'
Publikováno v:
Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 128:863-872
In salt depleted crayfish net sodium and proton fluxes were coupled 1:1 as required by the frog skin–turtle bladder model. In addition, three proton pump inhibitors produced equal reductions of both fluxes. It is concluded that the model operates i
Autor:
Leonard B. Kirschner
Publikováno v:
Comprehensive Physiology
The sections in this article are: 1 Physical Background 1.1 Dissipative Flows 2 Hyperosmotic Regulation 2.1 Reducing Dissipative Flows 2.2 Compensatory Flows: Water 2.3 Compensatory Flows: Active Ion Absorption 2.4 The Frog Skin Model: Symmetric Solu
Autor:
Leonard B. Kirschner
Publikováno v:
Journal of Experimental Zoology. 271:243-252
Autor:
Leonard B. Kirschner
Publikováno v:
Journal of Experimental Zoology. 267:19-26
The major mechanisms of urea turnover and of active ion transport in osmoregula- tory organs are reviewed. Using published values for the molecular flow through these systems it is possible to estimate the energetic cost of osmotic regulation in hypo
Autor:
Leonard B. Kirschner, Ana M. Zetino
Publikováno v:
Journal of Experimental Zoology. 265:366-372
Chloride channels in isolated amphibian skins have been shown to be open (high PCi) when the transepithelial potential (TEP) across the skin is >30 mV, inside positive, and [Cl−] in the external medium is high. In the absence of either of these sig
Publikováno v:
The FASEB Journal. 20
Autor:
Leonard B. Kirschner
Publikováno v:
The Journal of experimental biology. 207(Pt 9)
SUMMARYThe emphasis in this review will be on Na+ absorption across the skin and gills of vertebrates and the gills of crustaceans. However, some recent studies of Cl– uptake, especially in crustaceans, will also be described.
Autor:
Leonard B. Kirschner
Publikováno v:
Biochimica et biophysica acta. 1566(1-2)
Recently, three proton pump inhibitors were shown to have no effect on proton excretion and little on Na uptake in tapwater-adapted (TW) crayfish, while all three reduced Na–H exchange in salt-depleted (SD) animals. It appeared that the exchange wa
Publikováno v:
The Journal of Membrane Biology. 82:49-57
Apical cell membranes from Na+-transporting epithelia were identified in centrifugal fractions prepared from homogenates of rainbow trout kidney, gill and frog skin using a spin-labeled, nitroxide derivative of amiloride and electron paramagnetic res
Publikováno v:
Journal of Comparative Physiology B. 157:461-467
A primary mechanism of amino acid inhibition of intestinal alkaline phosphatase is postulated to be the formation of a dissociable enzyme-amino acid complex at an allosteric zinc site. The degree of inhibition was highly correlated with the Zn2+ stab