Zobrazeno 1 - 10
of 358
pro vyhledávání: '"Leonard B. Bacharier"'
Autor:
Mark L. Levy, Leonard B. Bacharier, Eric Bateman, Louis-Philippe Boulet, Chris Brightling, Roland Buhl, Guy Brusselle, Alvaro A. Cruz, Jeffrey M. Drazen, Liesbeth Duijts, Louise Fleming, Hiromasa Inoue, Fanny W. S. Ko, Jerry A. Krishnan, Kevin Mortimer, Paulo M. Pitrez, Aziz Sheikh, Arzu Yorgancıoğlu, Helen K. Reddel
Publikováno v:
npj Primary Care Respiratory Medicine, Vol 33, Iss 1, Pp 1-13 (2023)
Abstract The Global Initiative for Asthma (GINA) was established in 1993 by the World Health Organization and the US National Heart Lung and Blood Institute to improve asthma awareness, prevention and management worldwide. GINA develops and publishes
Externí odkaz:
https://doaj.org/article/dd505e9d9081431bb9d495ee006b72e6
Autor:
Charles Washington, Matthew Dapas, Arjun Biddanda, Kevin M. Magnaye, Ivy Aneas, Britney A. Helling, Brooke Szczesny, Meher Preethi Boorgula, Margaret A. Taub, Eimear Kenny, Rasika A. Mathias, Kathleen C. Barnes, CAAPA, Gurjit K. Khurana Hershey, Carolyn M. Kercsmar, Jessica D. Gereige, Melanie Makhija, Rebecca S. Gruchalla, Michelle A. Gill, Andrew H. Liu, Deepa Rastogi, William Busse, Peter J. Gergen, Cynthia M. Visness, Diane R. Gold, Tina Hartert, Christine C. Johnson, Robert F. Lemanske, Fernando D. Martinez, Rachel L. Miller, Dennis Ownby, Christine M. Seroogy, Anne L. Wright, Edward M. Zoratti, Leonard B. Bacharier, Meyer Kattan, George T. O’Connor, Robert A. Wood, Marcelo A. Nobrega, Matthew C. Altman, Daniel J. Jackson, James E. Gern, Christopher G. McKennan, Carole Ober
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-16 (2022)
Abstract Background Asthma is the most common chronic disease in children, occurring at higher frequencies and with more severe disease in children with African ancestry. Methods We tested for association with haplotypes at the most replicated and si
Externí odkaz:
https://doaj.org/article/0d8b1bafd774497eb37ab1773c9c191e
Autor:
Naomi G. Wilson, Ariel Hernandez-Leyva, Anne L. Rosen, Natalia Jaeger, Ryan T. McDonough, Jesus Santiago-Borges, Michael A. Lint, Thomas R. Rosen, Christopher P. Tomera, Leonard B. Bacharier, S. Joshua Swamidass, Andrew L. Kau
Publikováno v:
iScience, Vol 26, Iss 2, Pp 105991- (2023)
Summary: The gut microbiota in early childhood is linked to asthma risk, but may continue to affect older patients with asthma. Here, we profile the gut microbiota of 38 children (19 asthma, median age 8) and 57 adults (17 asthma, median age 28) by 1
Externí odkaz:
https://doaj.org/article/c0fb2dcfcaef44e186901a951eace0a3
Autor:
Cassandra Suther, Liv Devon, Lauren Daddi, Adam Matson, Hunter Panier, Hanshu Yuan, Katarzyna Saar, Suresh Bokoliya, Yair Dorsett, David A. Sela, Avraham Beigelman, Leonard B. Bacharier, Matthew D. Moore, Yanjiao Zhou
Publikováno v:
Journal of Functional Foods, Vol 97, Iss , Pp 105249- (2022)
Asthma is associated with significant morbidity. The gut microbiome has been shown to effect asthma development and exacerbation. In this study, we tested an oral supplement containing Boswellia serrata (Indian frankincense) tree resin on allergic pu
Externí odkaz:
https://doaj.org/article/953cb314e81c42a58043c930c78040e6
Autor:
Kathleen A. Lee-Sarwar, Kasper Fischer-Rasmussen, Klaus Bønnelykke, Hans Bisgaard, Bo Chawes, Rachel S. Kelly, Jessica Lasky-Su, Robert S. Zeiger, George T. O’Connor, Leonard B. Bacharier, Vincent J. Carey, Nancy Laranjo, Augusto A. Litonjua, Scott T. Weiss
Publikováno v:
Nutrients, Vol 15, Iss 10, p 2416 (2023)
Associations of omega-3 fatty acids (n-3) with allergic diseases are inconsistent, perhaps in part due to genetic variation. We sought to identify and validate genetic variants that modify associations of n-3 with childhood asthma or atopy in partici
Externí odkaz:
https://doaj.org/article/bec748d0ec7d4da98d01bb7e23fe64e7
Autor:
Chris McKennan, Katherine Naughton, Catherine Stanhope, Meyer Kattan, George T. O’Connor, Megan T. Sandel, Cynthia M. Visness, Robert A. Wood, Leonard B. Bacharier, Avraham Beigelman, Stephanie Lovinsky-Desir, Alkis Togias, James E. Gern, Dan Nicolae, Carole Ober
Publikováno v:
Epigenetics, Vol 16, Iss 6, Pp 662-676 (2021)
Epigenetic architecture is influenced by genetic and environmental factors, but little is known about their relative contributions or longitudinal dynamics. Here, we studied DNA methylation (DNAm) at over 750,000 CpG sites in mononuclear blood cells
Externí odkaz:
https://doaj.org/article/f03de818f7e542c49fd3940791be0e68
Autor:
Maleewan Kitcharoensakkul, Leonard B. Bacharier, Huiqing Yin‐Declue, Jonathan S. Boomer, Geneline Sajol, Marilyn K. Leung, Brad Wilson, Kenneth B. Schechtman, John P. Atkinson, Jonathan M. Green, Mario Castro
Publikováno v:
Immunity, Inflammation and Disease, Vol 8, Iss 1, Pp 30-39 (2020)
Abstract Background Infants with severe respiratory syncytial virus (RSV) bronchiolitis have an increased risk of recurrent wheezing and asthma. We aimed to evaluate the relationships between regulatory T cell (Treg) percentage and cytokine productio
Externí odkaz:
https://doaj.org/article/d8f84650c5654a90b09766106a09453e
Autor:
Natalia Jaeger, Ryan T. McDonough, Anne L. Rosen, Ariel Hernandez-Leyva, Naomi G. Wilson, Michael A. Lint, Emilie V. Russler-Germain, Jiani N. Chai, Leonard B. Bacharier, Chyi-Song Hsieh, Andrew L. Kau
Publikováno v:
Cell Reports, Vol 38, Iss 4, Pp 110324- (2022)
Externí odkaz:
https://doaj.org/article/dfc1eba520a44b809f4cb2543e2abaf2
Autor:
Yanjiao Zhou, Daniel Jackson, Leonard B. Bacharier, David Mauger, Homer Boushey, Mario Castro, Juliana Durack, Yvonne Huang, Robert F. Lemanske, Gregory A. Storch, George M. Weinstock, Kristine Wylie, Ronina Covar, Anne M. Fitzpatrick, Wanda Phipatanakul, Rachel G. Robison, Avraham Beigelman
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
How the airway microbiome influences asthma pathophysiology remains unclear. Here, the authors analyse nasal samples of cohort of school-age children with persistent asthma and find that the microbiota’s patterns and composition at time of early lo
Externí odkaz:
https://doaj.org/article/3c7d234b3d824ae79d9cd5e744d0de74
Autor:
Ricardo daSilva Antunes, Aaron Sutherland, April Frazier, Veronique Schulten, Anna Pomés, Jill Glesner, Agustin Calatroni, Matthew C. Altman, Robert A. Wood, George T. O'Connor, Jacqueline A. Pongracic, Gurjit K. Khurana Hershey, Carolyn M. Kercsmar, Rebecca S. Gruchalla, Michelle Gill, Andrew H. Liu, Edward Zoratti, Meyer Kattan, Paula J. Busse, Leonard B. Bacharier, Stephen J. Teach, Lisa M. Wheatley, Alkis Togias, William W. Busse, Daniel J. Jackson, Alessandro Sette
Publikováno v:
Clinical and Translational Allergy, Vol 11, Iss 8, Pp n/a-n/a (2021)
Abstract Background Characterization of allergic responses to cockroach (CR), a common aeroallergen associated with asthma, has focused mainly on IgE reactivity, but little is known about T cell responses, particularly in children. We conducted a fun
Externí odkaz:
https://doaj.org/article/78dd90c62c9a490ca2600a7f3eba12db