Zobrazeno 1 - 10
of 256
pro vyhledávání: '"Leonard A. Herzenberg"'
Publikováno v:
Immune Modulating Agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e960e77949d8c19aa6d1c283617f6da
https://doi.org/10.1201/9781003064671-11
https://doi.org/10.1201/9781003064671-11
Autor:
Kevin V. Lemley, James P. Andrus, Frank J. T. Staal, Stephen W. Ela, Pietro Ghezzi, Bita Sahaf, Richard E. Frye, Farook Jahoor, Andrew R. Zolopa, Dean P. Jones, Neil Kaplowitz, Richard Kopke, Kondala R. Atkuri, Leonard A. Herzenberg, John J. Mantovani, Hajime Nakamura, Kartoosh Heydari, Stephen C. De Rosa, Rabindra Tirouvanziam, Arne Holmgren, Teodoro Bottiglieri, Leonore A. Herzenberg, Ian A. Cotgreave
Publikováno v:
The Therapeutic Use of N-Acetylcysteine (NAC) in Medicine ISBN: 9789811053108
Glutathione (GSH) deficiency may play a pivotal role in a variety of apparently unrelated clinical conditions and diseases. Orally administered N-acetylcysteine (NAC), which replenishes the cysteine required for GSH synthesis, has been tested in a la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c14372c8658a189612dc0273e4cc4b54
https://doi.org/10.1007/978-981-10-5311-5_20
https://doi.org/10.1007/978-981-10-5311-5_20
Autor:
Leonard A. Herzenberg, Stephen W. Ela, Arne Holmgren, Pietro Ghezzi, Kartoosh Heydari, Leonore A. Herzenberg, Dean P. Jones, Neil Kaplowitz, Teodoro Bottiglieri, Richard Kopke, Rabindra Tirouvanziam, John J. Mantovani, Hajime Nakamura, Kevin V. Lemley, James P. Andrus, Frank J. T. Staal, Ian A. Cotgreave, Kondala R. Atkuri, Bita Sahaf, Farook Jahoor, Richard E. Frye, Andrew R. Zolopa, Stephen C. De Rosa
Publikováno v:
The Therapeutic Use of N-Acetylcysteine (NAC) in Medicine ISBN: 9789811053108
Besides understanding the effectiveness of N-acetylcysteine (NAC) for the treatment of disease and its effect on physiological systems, other considerations of NAC are important, including the pharmacology, formulations, and adverse effects of NAC. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61406f61bf07633ea237eb34a8a08377
https://doi.org/10.1007/978-981-10-5311-5_21
https://doi.org/10.1007/978-981-10-5311-5_21
Publikováno v:
Drug Development Research. 76:251-258
Preclinical Research Although acetaminophen (APAP) is an effective analgesic and anti-pyretic, APAP overdose is the most frequent cause of serious, often lethal, drug-induced hepatotoxicity. Administration of N-acetyl cysteine (NAC) within 8 hours of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b82483120de85eb4eb35809c1affcf93
https://doi.org/10.1002/ddr.21262
https://doi.org/10.1002/ddr.21262
Autor:
Lucia Coppo, Eva-Maria Hanschmann, Manuela Mengozzi, Lisa Mullen, Sandra Sacre, Christopher Horst Lillig, Sonia Salzano, Kondala R. Atkuri, Leonore A. Herzenberg, Philippe Chan, Pietro Ghezzi, Bita Sahaf, Paola Checconi, Leonard A. Herzenberg, David Vaudry, Lucas D. Bowler
Publikováno v:
Proceedings of the National Academy of Sciences. 111:12157-12162
The mechanism by which oxidative stress induces inflammation and vice versa is unclear but is of great importance, being apparently linked to many chronic inflammatory diseases. We show here that inflammatory stimuli induce release of oxidized peroxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6f70c5f1f1e0e86473c10e31aad87f9
https://doi.org/10.1073/pnas.1401712111
https://doi.org/10.1073/pnas.1401712111
Publikováno v:
Annual Review of Physiology. 76:1-20
Leonard and Leonore Herzenberg have left an indelible mark on the fields of immunology and cell biology, both in research and clinical aspects. They are perhaps best known for developing the technologies of fluorescence flow cytometry and hybridomas.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cfa0518537f6d8b266ab9a7d516074f
https://doi.org/10.1146/annurev-physiol-021113-170355
https://doi.org/10.1146/annurev-physiol-021113-170355
Autor:
Hiroshi Nagashima, Kazuaki Nakano, Leonard A. Herzenberg, Toshihiro Kobayashi, Hiromitsu Nakauchi, Kazuhiro Umeyama, Masahito Watanabe, Tomoyuki Yamaguchi, Hitomi Matsunari, Ryo Sumazaki, Masaki Nagaya
Publikováno v:
Proceedings of the National Academy of Sciences. 110:4557-4562
In the field of regenerative medicine, one of the ultimate goals is to generate functioning organs from pluripotent cells, such as ES cells or induced pluripotent stem cells (PSCs). We have recently generated functional pancreas and kidney from PSCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b27223c3a6aef24cd943bdc71f7cf06
https://doi.org/10.1073/pnas.1222902110
https://doi.org/10.1073/pnas.1222902110
Autor:
Leonard A. Herzenberg, Leonore A. Herzenberg, Bita Sahaf, David B. Miklos, Yang Yang, Sally Arai
Publikováno v:
Proceedings of the National Academy of Sciences. 110:3005-3010
B cells are known to play an important role in pathogenesis of human chronic graft vs. host disease (cGVHD). Our group has previously shown that IgG allo-antibodies recognize Y chromosome-encoded proteins (H–Y) and a dominant H–Y epitope, DEAD bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15b04d388f47b63d5d7f36f0b83704f4
https://doi.org/10.1073/pnas.1222900110
https://doi.org/10.1073/pnas.1222900110
Publikováno v:
Journal of Biological Chemistry. 288:687-702
Like our own lives, the National Institutes of Health (NIH) in the late 1950s was an exciting work in progress. Transplanted from the Monod laboratory at the core of the Escherichia coli microbial genetics revolution in Paris, we tumbled unceremoniou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698a8ea136641d3d9d7b05cfc960b44a
https://doi.org/10.1074/jbc.x112.426742
https://doi.org/10.1074/jbc.x112.426742
Autor:
Eliver Ghosn, Ryo Yamamoto, Leonore A. Herzenberg, Leonard A. Herzenberg, Sanae Hamanaka, Yang Yang, Hiromitsu Nakauchi
Publikováno v:
Proceedings of the National Academy of Sciences. 109:5394-5398
The question of whether a single hematopoietic stem cell (HSC) gives rise to all of the B-cell subsets [B-1a, B-1b, B-2, and marginal zone (MZ) B cells] in the mouse has been discussed for many years without resolution. Studies here finally demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56591c3997cf38a81551c7658c9099f0
https://doi.org/10.1073/pnas.1121632109
https://doi.org/10.1073/pnas.1121632109