Výsledky vyhledávání - "Leonard McDonald"

Simulations of Si(Li) x-ray detector response

Autor: John Campbell, Leonard McDonald, Tibor Papp, Theodore L. Hopman

Publikováno v: X-Ray Spectrometry. 30:230-241

Si(Li) lineshapes are generated using a model that incorporates Monte Carlo simulation of the interactions of the incident photon, a very simple approach to energy deposition by the primary (Auger and photo-) electrons, and an analytical approximatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1768344fad3d781a1cfe6b6d9c866381
https://doi.org/10.1002/xrs.492

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Discovery of (2S,4R)-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid hydrochloride (GAP-134)13, an orally active small molecule gap-junction modifier for the treatment of atrial fibrillation

Autor: Edward H. Kerns, Eric I. Rossman, Leonard McDonald, James K. Hennan, Qiang Wang, Bjarne Due Larsen, Christine Huselton, Li Di, John A. Butera, Kun Liu, Jørgen Søøøøøberg Petersen, Asaf Alimardanov, Gwen A. Morgan, Rayomand Unwalla, Robert E. Swillo

Publikováno v: Journal of medicinal chemistry. 52(4)

Rotigaptide (3) is an antiarrhythmic peptide that improves cardiac conduction by modifying gap-junction communication. Small molecule gap-junction modifiers with improved physical properties were identified from a Zealand Pharma peptide library using

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::566ea6a7cc1a58626de0e37de647e136
https://pubmed.ncbi.nlm.nih.gov/19175320

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Akademický článek

Discovery of (2S,4R)-1-(2-Aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic Acid Hydrochloride (GAP-134)13, an Orally Active Small Molecule Gap-Junction Modifier for the Treatment of Atrial Fibrillation.

Autor: John A. Butera, Bjarne Due Larsen, James K. Hennan, Edward Kerns, Li Di, Asaf Alimardanov, Robert E. Swillo, Gwen A. Morgan, Kun Liu, Qiang Wang, Eric I. Rossman, Rayomand Unwalla, Leonard McDonald, Christine Huselton, Jørgen S. Petersen

Publikováno v: Journal of Medicinal Chemistry; Feb2009, Vol. 52 Issue 4, p908-911, 4p

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Enantiomeric separation and determination of absolute stereochemistry of asymmetric molecules in drug discovery—Building chiral technology toolboxesIn contrast to previous usage, Chiral Technology is defined in this review as the use of techniques or tools for the determination of absolute stereochemistry, the chiral analysis or preparative separation of racemic small molecules containing one or more asymmetric centers into (all of) their enantiomers (= enantiomeric or chiral separation), and the facilitation of asymmetric transformations, but not asymmetric transformations themselves. The terms Chiral Technology and Chirotechnology have often been used as a general category for asymmetric transformations using enzymes, chiral building blocks, chiral auxiliaries, and chiral catalysts, as well as chiral salt resolution.1–13

Publikováno v: Chirality; Sep2007, Vol. 19 Issue 9, p658-682, 25p

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Ethical dilemmas facing an archivist in the business environment: The constraints on a business archivist

Autor: Leonard McDonald

Publikováno v: Journal of the Society of Archivists. 10:168-172

(1989). Ethical dilemmas facing an archivist in the business environment: The constraints on a business archivist. Journal of the Society of Archivists: Vol. 10, No. 4, pp. 168-172.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::955028c0a9f477d1430032253168e424
https://doi.org/10.1080/00379818909514379

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Periodical

PEOPLE WATCH.

Publikováno v: Plastics News. 9/27/2004, Vol. 16 Issue 30, p13-13. 1/3p. 5 Color Photographs, 1 Black and White Photograph.

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Molecular and phenotypic comparison of phaeochromycin-producing strains of Streptomyces phaeochromogenes and Streptomyces ederensis.

Autor: Ritacco, Frank V.¹ ritaccf@wyeth.com, Eveleigh, Douglas E.²

Publikováno v: Journal of Industrial Microbiology & Biotechnology. Sep2008, Vol. 35 Issue 9, p931-945. 15p. 7 Diagrams, 5 Charts.

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Laser–visual–inertial odometry and mapping with high robustness and low drift.

Autor: Zhang, Ji, Singh, Sanjiv

Publikováno v: Journal of Field Robotics; Dec2018, Vol. 35 Issue 8, p1242-1264, 23p

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Records management and conservation: Conflicting objectives.

Autor: Cameron, Alan

Publikováno v: Journal of the Society of Archivists. Spring91, Vol. 12 Issue 1, p36. 6p. 2 Diagrams, 1 Chart, 1 Graph.

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