Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Leonard, Y.M."'
Autor:
Karine Rizzoti, Leonard Y.M. Cheung
Publikováno v:
Journal of Molecular Endocrinology. 65:R35-R51
In the last 15 years, single-cell technologies have become robust and indispensable tools to investigate cell heterogeneity. Beyond transcriptomic, genomic and epigenome analyses, technologies are constantly evolving, in particular toward multi-omics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c6f52f8e030a6848c12d657f2f234e
https://doi.org/10.1530/jme-19-0276
https://doi.org/10.1530/jme-19-0276
Publikováno v:
In Cellular Endocrinology in Health and Disease Edition: Second Edition. 2021:79-91
The pituitary gland is an organ with a low rate of cell turnover. While differentiated hormone-producing cells can re-enter the cell cycle, most of these cells are not dividing. There is some evidence that the pituitary can undergo limited regenerati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d932323717a1f87181f1634de97c25d9
https://doi.org/10.1016/b978-0-12-819801-8.00003-x
https://doi.org/10.1016/b978-0-12-819801-8.00003-x
Autor:
Ana Aranda, Denise D. Belsham, Véronique Bozon, Maria Luisa Brandi, Giulia Brigante, Gilles Bruneau, Sally A. Camper, Livio Casarini, Juan M. Castellano, Leonard Y.M. Cheung, Luisella Cianferotti, Frédérique Clément, Lique M. Coolen, Pascale Crépieux, Prasad Dalvi, Lily Q. Dong, Shereen Ezzat, Tatiana Fiordelisio, Robert C. Fowkes, Laurine Gagniac, Nathalie Gallay, Zu-hua Gao, Peter D. Gluckman, Karen Gomez-Hernandez, Robert L. Goodman, Florian Guillou, Jason T. Hadley, Mark A. Hanson, Aylin C. Hanyaloglu, Tomohiro Ishii, Jo Ann Janovick, Frédéric Jean-Alphonse, José Nicolás Jiménez, Constanza Contreras Jurado, Nancy Kaddour, Michael N. Lehman, Jun-Li Liu, Zhenqi Liu, Neruja Loganathan, Felicia M. Low, Olaia Martínez-Iglesias, Craig A. McArdle, Emma K. Mcilwraith, Moises Mercado, Francesco De Pascali, Lucie P. Pellissier, María Inés Pérez Millán, Hanna Pincas, Anne Poupon, Pauline Raynaud, Eric Reiter, Elvira Rodríguez-Vázquez, Cecilia Romagnoli, Frederique Ruf-Zamojski, Lidia Ruiz-Llorente, Jiyoon Ryu, Daniele Santi, Stuart C. Sealfon, Manuela Simoni, Shifa Tahir, Toru Tateno, Manuel Tena-Sempere, Nimbe Torres, Armando R. Tovar, Andy Tran, Krasimira Tsaneva-Atanasova, Judith L. Turgeon, Alfredo Ulloa-Aguirre, Ariana Vargas-Castillo, Jean-Pierre Vilardaga, Margaritis Voliotis, Alex D. White, Viktoria Xega, Romain Yvinec, Teresa Zariñán
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::376618ce6a4e0872577653638c8979e0
https://doi.org/10.1016/b978-0-12-819801-8.09992-0
https://doi.org/10.1016/b978-0-12-819801-8.09992-0
Autor:
Lindsey Anne Dudley, Alexandre Zacharie Daley, Sally A. Camper, Amanda H. Mortensen, Michelle L. Brinkmeier, Leonard Y.M. Cheung, Rachna Sridhar
Publikováno v:
Journal of the Endocrine Society
Many transcription factors have been identified that are important for specification and differentiation of the hormone-producing cells of the pituitary gland. For example, POU1F1 is essential for differentiation of thyrotropes, somatotropes, and lac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1222a5d7105feebe778a12a53614944
http://europepmc.org/articles/PMC7209132
http://europepmc.org/articles/PMC7209132
Publikováno v:
Journal of the Endocrine Society
We implemented single-cell RNA sequencing (scRNAseq) technology as a discovery tool to identify factors enriched in differentiated thyrotropes. Thyroid-stimulating hormone (TSH) is produced in the pars distalis of the anterior pituitary (AP) and prim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ba77342d66680dcdadeac61cd03438
https://doi.org/10.1210/jendso/bvaa046.655
https://doi.org/10.1210/jendso/bvaa046.655
Publikováno v:
Journal of the Endocrine Society
Recent genome wide association studies have begun to identify loci that are risk factors for sporadic pituitary adenomas, but the genes associated with these loci are unknown. In general, ~90% of GWAS hits are in noncoding regions, making it difficul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6062611e280b04d6ac83d3369e7745a2
https://doi.org/10.1210/jendso/bvaa046.1660
https://doi.org/10.1210/jendso/bvaa046.1660
Autor:
Alexandre Z. Daly, Stacey McGee, Buffy S. Ellsworth, Akima S. George, Michelle L. Brinkmeier, Leonard Y.M. Cheung, Sally A. Camper
Publikováno v:
Endocrinology. 159:3910-3924
Transcription factors and signaling pathways that regulate stem cells and specialized hormone-producing cells in the pituitary gland have been the subject of intense study and have yielded a mechanistic understanding of pituitary organogenesis and di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de13ba66cefdac5d32a34170849ab04e
https://doi.org/10.1210/en.2018-00750
https://doi.org/10.1210/en.2018-00750
Publikováno v:
Journal of the Endocrine Society
A fundamental question for pituitary development and disease is to understand the mechanisms that regulate proliferation, quiescence, and differentiation of stem cells and endocrine lineage-committed precursor cells. Pituitary stem cells, marked by e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8268c01ac9af09decf1285614d42962c
http://europepmc.org/articles/PMC8090533
http://europepmc.org/articles/PMC8090533
Publikováno v:
Molecular and Cellular Endocrinology. 439:213-223
The hypothalamic-pituitary axes are the coordinating centers for multiple endocrine gland functions and physiological processes. Defects in the hypothalamus or pituitary gland can cause reduced growth and severe short stature, affecting approximately
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0affe1e350f0604665d8916f3bdb6886
https://doi.org/10.1016/j.mce.2016.09.005
https://doi.org/10.1016/j.mce.2016.09.005