Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Leonard, Saltz"'
Autor:
Elizabeth S. Nakasone, Tyler J. Zemla, Ming Yu, She Yu Lin, Fang-Shu Ou, Kelly Carter, Federico Innocenti, Leonard Saltz, William M. Grady, Stacey A. Cohen
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
ABSTRACTWhile epigenomic alterations are common in colorectal cancers (CRC), few epigenomic biomarkers that risk-stratify patients have been identified. We thus sought to determine the potential of ZNF331 promoter hypermethylation (mZNF331) as a prog
Externí odkaz:
https://doaj.org/article/9934e8c678554cc0aff190ec4294bfc1
Autor:
Jun Yin, Shaheenah Dawood, Romain Cohen, Jeff Meyers, John Zalcberg, Takayuki Yoshino, Matthew Seymour, Tim Maughan, Leonard Saltz, Eric Van Cutsem, Alan Venook, Hans-Joachim Schmoll, Richard Goldberg, Paulo Hoff, J. Randolph Hecht, Herbert Hurwitz, Cornelis Punt, Eduard Diaz Rubio, Miriam Koopman, Chiara Cremolini, Volker Heinemann, Christophe Tournigard, Carsten Bokemeyer, Charles Fuchs, Niall Tebbutt, John Souglakos, Jean-Yves Doulliard, Fairooz Kabbinavar, Benoist Chibaudel, Aimery de Gramont, Qian Shi, Axel Grothey, Richard Adams
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Background: Benchmarking international cancer survival differences is necessary to evaluate and improve healthcare systems. Our aim was to assess the potential regional differences in outcomes among patients with metastatic colorectal cancer (mCRC) p
Externí odkaz:
https://doaj.org/article/bf4aa20a3f6a47ca83257f0396cc016f
Autor:
Nitya Raj, Elizabeth Cruz, Sarah O'Shaughnessy, Claudia Calderon, Joanne F. Chou, Marinela Capanu, Olivia Heffernan, April DeMore, Sippy Punn, Tiffany Le, Haley Hauser, Leonard Saltz, Diane Reidy-Lagunes
Publikováno v:
JCO oncology practice. 18(9)
PURPOSE: Somatostatin analogs octreotide long-acting release (octLAR) and lanreotide are equally acceptable in National Comprehensive Cancer Network guidelines for neuroendocrine tumors (NETs). Lanreotide is more expensive and given by deep subcutane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::350b8ac130d87135d5a56ae7ae427a40
https://pubmed.ncbi.nlm.nih.gov/35724357
https://pubmed.ncbi.nlm.nih.gov/35724357
Autor:
Jaclyn F. Hechtman, Ahmet Zehir, Marc Ladanyi, Leonard Saltz, David S. Klimstra, Jiajing Wang, Robert Cimera, Lu Wang, Michael F. Berger, Kevin P. O'Rourke, Jinru Shia, Sumit Middha, Rona Yaeger, Carlos Pagan, Ryan N. Ptashkin
Supplemental Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22af14fb354bc268969e52b06d081269
https://doi.org/10.1158/1541-7786.22515813
https://doi.org/10.1158/1541-7786.22515813
Autor:
Marc Ladanyi, Leonard Saltz, Efsevia Vakiani, Jinru Shia, Laetitia Borsu, Maria E. Arcila, David Solit, David M. Hyman, Tao Zheng, Sumit Middha, Lu Wang, Rona Yaeger, Ahmet Zehir, Jaclyn F. Hechtman
Detected RTK alterations and MAP2K1 mutations in sequenced colorectal carcinomas.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38909cc6583f035eebadbac1d95e87ab
https://doi.org/10.1158/1541-7786.22511155
https://doi.org/10.1158/1541-7786.22511155
Autor:
Jaclyn F. Hechtman, Ahmet Zehir, Marc Ladanyi, Leonard Saltz, David S. Klimstra, Jiajing Wang, Robert Cimera, Lu Wang, Michael F. Berger, Kevin P. O'Rourke, Jinru Shia, Sumit Middha, Rona Yaeger, Carlos Pagan, Ryan N. Ptashkin
(a) Barplot of GISTIC2.0 chromosome 20q gene level copy number calls in TCGA COADREAD data and (b) chromosome 20q genes covered by MSK-IMPACT. (c) Interquartile range (IGR) of gene level RNASeq expression z-score by copy number group from 2a. (d) MSK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b21d817a8efeb32a250b46b6d6f4a21
https://doi.org/10.1158/1541-7786.22515807
https://doi.org/10.1158/1541-7786.22515807
Autor:
Jaclyn F. Hechtman, Ahmet Zehir, Marc Ladanyi, Leonard Saltz, David S. Klimstra, Jiajing Wang, Robert Cimera, Lu Wang, Michael F. Berger, Kevin P. O'Rourke, Jinru Shia, Sumit Middha, Rona Yaeger, Carlos Pagan, Ryan N. Ptashkin
(a) Plot of SCNA in a CRC with 20q amplification as detected by MSK-IMPACT and (b) high resolution SNP analysis on Oncoscan confirmed the results without showing focal amplifications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df33e72fe1b55092f6435b2e84837fe1
https://doi.org/10.1158/1541-7786.22515810
https://doi.org/10.1158/1541-7786.22515810
Autor:
Jaclyn F. Hechtman, Ahmet Zehir, Marc Ladanyi, Leonard Saltz, David S. Klimstra, Jiajing Wang, Robert Cimera, Lu Wang, Michael F. Berger, Kevin P. O'Rourke, Jinru Shia, Sumit Middha, Rona Yaeger, Carlos Pagan, Ryan N. Ptashkin
Here, comprehensive analysis was performed on the molecular and clinical features of colorectal carcinoma harboring chromosome 20q amplification. Tumor and normal DNA from patients with advanced colorectal carcinoma underwent next-generation sequenci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1d2d020eb4270c4c7d9c30460550cde
https://doi.org/10.1158/1541-7786.c.6541194
https://doi.org/10.1158/1541-7786.c.6541194
Autor:
Jaclyn F. Hechtman, Ahmet Zehir, Marc Ladanyi, Leonard Saltz, David S. Klimstra, Jiajing Wang, Robert Cimera, Lu Wang, Michael F. Berger, Kevin P. O'Rourke, Jinru Shia, Sumit Middha, Rona Yaeger, Carlos Pagan, Ryan N. Ptashkin
Supplemental Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a9382ff3a7fea58b0118c93698f6bfb
https://doi.org/10.1158/1541-7786.22515816
https://doi.org/10.1158/1541-7786.22515816
Autor:
Rona Yaeger, Marinela Capanu, Leonard Saltz, Nancy Kemeny, Jaclyn F. Hechtman, Joanne F. Chou, Maria Ignez Braghiroli, Andrea Cercek
Purpose: NRAS mutations are now routinely included in RAS testing prior to EGFR inhibitor therapy for metastatic colorectal cancer (mCRC). The clinical implications of NRAS mutation beyond lack of response to anti-EGFR therapy, however, are not known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a23444a50df21cf5a354fe5246998f
https://doi.org/10.1158/1078-0432.c.6525212.v1
https://doi.org/10.1158/1078-0432.c.6525212.v1