Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Leonard, Frisbie"'
Autor:
Leonard Frisbie, Catherine Pressimone, Emma Dyer, Roja Baruwal, Geyon Garcia, Claudette St. Croix, Simon Watkins, Michael Calderone, Grace Gorecki, Zaineb Javed, Huda I. Atiya, Nadine Hempel, Alexander Pearson, Lan G. Coffman
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114551- (2024)
Summary: Ovarian cancer is characterized by early metastatic spread. This study demonstrates that carcinoma-associated mesenchymal stromal cells (CA-MSCs) enhance metastasis by increasing tumor cell heterogeneity through mitochondrial donation. CA-MS
Externí odkaz:
https://doaj.org/article/fadc5372690c419fb9d343cb2641fa43
Autor:
Huda I. Atiya, Leonard Frisbie, Ester Goldfeld, Taylor Orellana, Nicole Donnellan, Francesmary Modugno, Michael Calderon, Simon Watkins, Rugang Zhang, Esther Elishaev, Thing Rinda Soong, Anda Vlad, Lan Coffman
Publikováno v:
Cancer Research. 82:4680-4693
Ovarian clear cell carcinoma (OCCC) is a deadly and treatment-resistant cancer, which arises within the unique microenvironment of endometriosis. In this study, we identified a subset of endometriosis-derived mesenchymal stem cells (enMSC) characteri
Autor:
Lan Coffman, Anda Vlad, Thing Rinda Soong, Esther Elishaev, Rugang Zhang, Simon Watkins, Michael Calderon, Francesmary Modugno, Nicole Donnellan, Taylor Orellana, Ester Goldfeld, Leonard Frisbie, Huda I. Atiya
Ovarian clear cell carcinoma (OCCC) is a deadly and treatment-resistant cancer, which arises within the unique microenvironment of endometriosis. In this study, we identified a subset of endometriosis-derived mesenchymal stem cells (enMSC) characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88961fa8e19abb38e2cb872c24bbf36d
https://doi.org/10.1158/0008-5472.c.6514212.v1
https://doi.org/10.1158/0008-5472.c.6514212.v1
Autor:
Lan Coffman, Anda Vlad, Thing Rinda Soong, Esther Elishaev, Rugang Zhang, Simon Watkins, Michael Calderon, Francesmary Modugno, Nicole Donnellan, Taylor Orellana, Ester Goldfeld, Leonard Frisbie, Huda I. Atiya
Supplementary figures and table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55154574b518b84b9fc47571aa68bf0b
https://doi.org/10.1158/0008-5472.22432671.v1
https://doi.org/10.1158/0008-5472.22432671.v1
Autor:
Catherine Pressimone, Leonard Frisbie, Emma Dyer, Roja Baruwal, Claudette St. Croix, Simon Watkins, Michael Calderone, Grace Gorecki, Zaineb Javed, Huda I Atiya, Nadine Hempel, Alexander Pearson, Lan Coffman
Ovarian cancer is characterized by early, diffuse metastatic spread with most women presenting with extensive abdominal metastasis at the time of diagnosis. Prior work demonstrated carcinoma-associated mesenchymal stem cells (CA-MSCs) enhance ovarian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afff1cf7fb72b606ef72362253fd668e
https://doi.org/10.1101/2022.09.21.506345
https://doi.org/10.1101/2022.09.21.506345
Publikováno v:
Gynecologic Oncology. 166:S62
Autor:
Ronald J. Buckanovich, Elizabeth L. Christie, Lan G. Coffman, Zachary T. Freeman, Leonard Frisbie, David D.L. Bowtell, Alexander T. Pearson
Publikováno v:
Stem Cells (Dayton, Ohio)
Carcinoma-associated mesenchymal stem cells (CA-MSCs) are critical stromal progenitor cells within the tumor microenvironment (TME). We previously demonstrated that CA-MSCs differentially express bone morphogenetic protein family members, promote tum
Publikováno v:
Journal of visualized experiments : JoVE. (169)
Ovarian cancer is characterized by early, diffuse metastasis with 70% of women having metastatic disease at the time of diagnosis. While elegant transgenic mouse models of ovarian cancer exist, these mice are expensive and take a long time to develop
Autor:
Hui Shen, Thomas R. Pisanic, Kelly K. Foy, Yeh Wang, Huihui Fan, Ie Ming Shih, Chelsea Chandler, Huda Atiya, Lan G. Coffman, Jeff Wang, Leonard Frisbie
SummaryOvarian cancer develops early intra-peritoneal metastasis establishing a supportive tumor microenvironment (TME) through reprogramming normal mesenchymal stem cells into carcinoma-associated mesenchymal stem cells (CA-MSCs). CA-MSCs are the st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c3996f8b0787735958d0e6451d2e97d
Publikováno v:
Advances in experimental medicine and biology. 1234
The interactions between tumor cells and the non-malignant stromal and immune cells that make up the tumor microenvironment (TME) are critical to the pathophysiology of cancer. Mesenchymal stem cells (MSCs) are multipotent stromal stem cells found wi