Výsledky vyhledávání - "Leona Trübe"

Akademický článek

Introducing Attribute Association Graphs to Facilitate Medical Data Exploration: Development and Evaluation Using Epidemiological Study Data

Autor: Louis Bellmann, Alexander Johannes Wiederhold, Leona Trübe, Raphael Twerenbold, Frank Ückert, Karl Gottfried

Publikováno v: JMIR Medical Informatics, Vol 12, p e49865 (2024)

BackgroundInterpretability and intuitive visualization facilitate medical knowledge generation through big data. In addition, robustness to high-dimensional and missing data is a requirement for statistical approaches in the medical domain. A method

Externí odkaz: https://doaj.org/article/ed0db302af9e4479b59a0831f2fe52d2

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The formins FHOD1 and INF2 regulate inter-and intra-structural contractility of podosomes

Autor: Linda Panzer, Stefan Linder, Ben Joosten, Matthias Klose, Leona Trübe, Johan A. Slotman, Alessandra Cambi

Publikováno v: Journal of Cell Science, 129(2), 298-313. Company of Biologists Ltd
Europe PubMed Central
Journal of Cell Science, 129, 298-313
Journal of Cell Science, 129, 2, pp. 298-313

Item does not contain fulltext Podosomes are actin-rich adhesion structures that depend on Arp2/3-complex-based actin nucleation. We now report the identification of the formins FHOD1 and INF2 as novel components and additional actin-based regulators

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aae12d8fcb9475ff32f911bb91b4188d
https://doi.org/10.1242/jcs.177691

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A novel marker, ARM58, confers antimony resistance to Leishmania spp

Autor: Dorothea Zander, Paloma Tejera Nevado, Vanessa Adaui, Jorge Arevalo, Andrea Nühs, Sonja Schmidt, Louis Maes, Carola Schäfer, Leona Trübe, Joachim Clos, Jean-Claude Dujardin

Publikováno v: International Journal for Parasitology: Drugs and Drug Resistance

Graphical abstract
Highlights • Functional cloning identifies a Leishmania-specific 58 kD antimony resistance marker, ARM58. • ARM58 overexpression confers antimony resistance. • A neighbouring, structurally related gene lacks antimony res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb0504146117358b8000a00199dd29d
https://doi.org/10.1016/j.ijpddr.2013.11.004

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Thr202Ala in thyA Is a Marker for the Latin American Mediterranean Lineage of the Mycobacterium tuberculosis Complex Rather than Para -Aminosalicylic Acid Resistance

Autor: Leona Trübe, John A.C. Archer, Claudio U. Köser, Stefan Niemann, Elvira Richter, Silke Feuerriegel, Sabine Rüsch Gerdes

Publikováno v: Antimicrobial Agents and Chemotherapy

Single nucleotide polymorphisms (SNPs) involved in the development of resistance represent powerful markers for the rapid detection of first- and second-line resistance in clinical Mycobacterium tuberculosis complex (MTBC) isolates. However, the asso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc841a5f010442ca02444ff701b45631
https://doi.org/10.1128/aac.00738-10

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