Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Leona Barclay"'
Autor:
Nigel G. Shrive, Ian Ky Lo, S. Holowaychuk, David A. Hart, Jerome B. Rattner, John R. Matyas, Cyril B. Frank, Leona Barclay, Yamini Achari, Paul Sciore
Publikováno v:
Scandinavian Journal of Medicine & Science in Sports. 21:543-553
Menisci help maintain the structural integrity of the knee. However, the poor healing potential of the meniscus following a knee injury can not only end a career in sports but lead to osteoarthritis later in life. Complete understanding of meniscal s
Autor:
Alfred Rademaker, Judy Chernos, Calvin Greene, Tina Hoang, Evelyn Ko, Leona Barclay, Renée H. Martin
Publikováno v:
Biology of Reproduction. 69:535-539
Infertile men undergoing intracytoplasmic sperm injection have an increased frequency of chromosome abnormalities in their sperm. Men with low sperm concentration (oligozoospermia) have an increased risk of sperm chromosome abnormalities. This study
Autor:
L. Leigh Field, Renée H. Martin, Alfred Rademaker, Evelyn Ko, Qinghua Shi, Leona Barclay, Elizabeth Spriggs
Publikováno v:
The American Journal of Human Genetics. 71:254-261
Recombination between the X and Y chromosomes is limited to the pseudoautosomal region and is necessary for proper segregation of the sex chromosomes during spermatogenesis. Failure of the sex chromosomes to disjoin properly during meiosis can result
Autor:
Jonna Eggerer, David A. Hart, Eric Vignon, Ivan G. Otterness, Leona Barclay, Marie-Pierre Hellio Le Graverand
Publikováno v:
Journal of Orthopaedic Research. 20:535-544
Osteoarthritis (OA) is the most common form of arthritis and patients with meniscal and ligament injuries of the knee are at high risk to develop the disease. The purpose of this study was to evaluate molecular and structural changes occurring in fou
Autor:
Leona Barclay, David A. Hart, Jerome B. Rattner, Marie-Pierre Hellio Le Graverand, Yongchung Ou, Takashi Natsume, Teresa Schield-Yee
Publikováno v:
Journal of Anatomy. 198:525-535
Four major morphologically distinct classes of cells were identified within the adult rabbit meniscus using antibodies to cytoskeletal proteins. Two classes of cell were present in the fibrocartilage region of the meniscus. These meniscal cells exhib
Autor:
Paul Sciore, Jerome B. Rattner, Jonna Eggerer, Eric Vignon, Leona Barclay, David A. Hart, J. P. Rattner, Marie-Pierre Hellio Le Graverand
Publikováno v:
Arthritis & Rheumatism. 44:1808-1818
Objective To determine the histologic changes that accompany the formation of cell clusters during the early stages of osteoarthritis development in the meniscus, and to characterize the expression phenotype of these cells. Methods Histologic section
Publikováno v:
American Journal of Medical Genetics. 99:34-38
To account for the increased proportion of paternal nondisjunction in 47,XXY males as compared to other trisomies, it has been suggested that the XY bivalent, with its reduced region of homology, is particularly susceptible to nondisjunction. Molecul
Publikováno v:
The American Journal of Human Genetics. 66(3):1149-1152
Hereditary nonpolyposis colon cancer (HNPCC) has been shown to be caused by mutations in the mismatch repair genes hMSH2, hMLH1, hPMS1, and hPMS2. Recent evidence has demonstrated that mutations in mismatch repair genes disrupt meiosis in mice. A lar
Publikováno v:
Human Genetics. 99:214-218
Sperm chromosome abnormalities were assessed in testicular cancer patients before and after treatment with BEP (bleomycin, etoposide, cisplatin). The frequencies of disomy for chromosomes 1, 12, X, Y and XY were assessed along with diploid frequencie
Publikováno v:
Cytogenetic and Genome Research. 78:120-123
Sperm karyotype analysis was performed on testicular cancer patients before and after treatment with BEP (bleomycin, etoposide, and cisplatin). A total of 788 sperm chromosome complements was studied, 236 before chemotherapy (CT) and 552 post-CT. The