Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Leon W. Hoyer"'
Autor:
Edward G. D. Tuddenham, Leon W. Hoyer, Carl A. Carta, Charles R. Rizza, Helen Armitage, Francis Rotblat
Publikováno v:
British Journal of Haematology. 55:493-507
Summary. The von Willebrand factor antigen (factor VIII-related antigen, VIIIR:Ag) multimer pattern has been analysed by SDS-agarose electrophoresis of plasmas from 116 patients (47 families) with von Willebrand's disease. In addition to previously r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4343f8af520197534094d21802e4d067
https://doi.org/10.1111/j.1365-2141.1983.00493.x
https://doi.org/10.1111/j.1365-2141.1983.00493.x
Autor:
K. Beeton, Simon A. Brown, C Peerlinck, Anne Goodeve, S Bolland, Christine A. Lee, Georges-Etienne Rivard, P Lollar, Leon W. Hoyer, Louis M. Aledort, M L Manco-Johnson, Craig M. Kessler, Nicholas J. Goddard, Rolf Ljung, Blanchette, Guglielmo Mariani, TW Barrowcliffe
Publikováno v:
Haemophilia. 7:313-320
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e58c51a0c4dc3c35c86f5e0b2fdd09f5
https://doi.org/10.1046/j.1365-2516.2001.00525.x
https://doi.org/10.1046/j.1365-2516.2001.00525.x
Autor:
Bianca M. Conti-Fine, Huiyun Wu, Ernie Parker, Jiahua Qian, David K. Okita, Mark T. Reding, Pete Lollar, Leon W. Hoyer
Publikováno v:
Thrombosis and Haemostasis. 85:125-133
SummaryMice genetically deficient in factor VIII (fVIII) are a model of hemophilia A. As a first step to reproduce in this mouse model what occurs over time in hemophilia A patients treated with human fVIII (hfVIII), we have investigated the time cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bd4e87c45a654c61297d1109989f86d
https://doi.org/10.1055/s-0037-1612915
https://doi.org/10.1055/s-0037-1612915
Publikováno v:
Blood. 95:1324-1329
Inhibitory antibody formation is a major complication of factor VIII replacement therapy in patients with hemophilia A. To better understand the pathogenesis of this immunologic reaction, we evaluated the role of T-cell costimulatory signals for anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87a71b2b3ae2627ec1e4fb9bb074b991
https://doi.org/10.1182/blood.v95.4.1324.004k25_1324_1329
https://doi.org/10.1182/blood.v95.4.1324.004k25_1324_1329
Publikováno v:
Thrombosis and Haemostasis. 81:240-244
SummaryIn order to understand better the mechanism of inhibitor formation in hemophilia A patients, we have characterized the immune response to human factor VIII in a murine model of hemophilia A. Mice with severe factor VIII deficiency caused by ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d7a80132e25e49cae0b8728a71b061
https://doi.org/10.1055/s-0037-1614450
https://doi.org/10.1055/s-0037-1614450
'For the blood is the life....'(Deut. 12 :23)'... because the blood, in its value as life, makes atonement'(Lev. 17: 11) HemoPhilia is a rare disease, severe hemophilia rarer still, yet the written history of hemophilia extends back over a millennium
Autor:
W.N. Drohan, Leon W. Hoyer
Recent progress in molecular biology has led to a rapid expansion of our understanding of the proteins that are essential for hemostasis and thrombosis. The goal of the XXI Annual Scientific Symposium of the American Red Cross was to provide a forum
Autor:
Randal J. Kaufman, Kagehiro Amano, Katerina Michaelides, Phillip M. Cacheris, David Ginsburg, Rainer Schwaab, Leon W. Hoyer, Mauro Silvério Figueiredo, William C. Nichols
Publikováno v:
Blood. 88:1183-1187
Although many examples of unrelated hemophilia A patients carrying identical point mutations in the factor VIII (FVIII) gene have been reported, the clinical phenotype is not always the same among patients sharing the same molecular defect. Possible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c35a9a80215146938789130bd7d16214
https://doi.org/10.1182/blood.v88.4.1183.bloodjournal8841183
https://doi.org/10.1182/blood.v88.4.1183.bloodjournal8841183
Publikováno v:
Blood. 86:2183-2190
Porcine factor VIII has been used successfully to treat factor VIII inhibitor patients whose plasmas have minimal cross-reactivity to porcine factor VIII. However, some inhibitor plasmas do inhibit porcine factor VIII, and the extent of procoagulant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b6aba7a2beff6f484805b650335e95d
https://doi.org/10.1182/blood.v86.6.2183.bloodjournal8662183
https://doi.org/10.1182/blood.v86.6.2183.bloodjournal8662183
Autor:
Leon W. Hoyer
Publikováno v:
British Journal of Haematology. 90:498-501
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ef73774443a9fb7950a1f6b5ee73dc
https://doi.org/10.1111/j.1365-2141.1995.tb05575.x
https://doi.org/10.1111/j.1365-2141.1995.tb05575.x