Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Leon S. Farhy"'
Publikováno v:
IEEE transactions on bio-medical engineering. 69(2)
According to the World Health Organization, about 422 million people worldwide have type 1 or type 2 diabetes (T1D, T2D), with the latter accounting for 90-95% of cases. Safe and effective treatment of patients with diabetes requires accurate and fre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c30bbc1217e01def86b1c5037e6b44
https://pubmed.ncbi.nlm.nih.gov/34375274
https://pubmed.ncbi.nlm.nih.gov/34375274
Autor:
Leon S. Farhy
Publikováno v:
The Journal of clinical endocrinology and metabolism. 106(8)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c248510b6ecc9395724331ae707267e
https://pubmed.ncbi.nlm.nih.gov/33567069
https://pubmed.ncbi.nlm.nih.gov/33567069
Autor:
Leon S Farhy, Alice eChan, Marc D Breton, Stacey M Anderson, Boris P Kovatchev, Anthony L McCall
Publikováno v:
Frontiers in Physiology, Vol 3 (2012)
Glucagon Counterregulation (GCR) protects against hypoglycemia, but is impaired in type 1 diabetes (T1DM). A model-based analysis of in vivo animal data predicts that the GCR defects are linked to basal hyperglucagonemia. To test this hypothesis we s
Externí odkaz:
https://doaj.org/article/da389de1441745aea4759bdab1c25c8a
Autor:
Anthony L. McCall, E. Andy Ortiz, Jennifer L. Kirby, James M. Isbell, Leon S. Farhy, Jennifer M. Lobo, Stephen D. Patek
Publikováno v:
ACC
Stress-induced hyperglycemia is common in critically ill patients, where elevated blood glucose and glycemic variability have been found to contribute to infection, slow wound healing, and short-term mortality. Early clinical studies demonstrated imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc0213f918a7f5146ba12c2c00112f47
https://pubmed.ncbi.nlm.nih.gov/31787804
https://pubmed.ncbi.nlm.nih.gov/31787804
Publikováno v:
Journal of Diabetes Science and Technology. 12:311-317
Aims: In type 1 diabetes (T1D), repeated hypoglycemic episodes may reduce hormonal defenses and increase the risk for severe hypoglycemia. In this work, we investigate the effect of a structured hyper/hypoglycemic metabolic challenge on the postinter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f4c0c770b47defaead234e59d54ac6
https://doi.org/10.1177/1932296817729392
https://doi.org/10.1177/1932296817729392
Autor:
Leon S. Farhy, Anthony L. McCall
Publikováno v:
Current Opinion in Clinical Nutrition and Metabolic Care. 18:407-414
Autoimmune destruction of the β cells is considered the key abnormality in type 1 diabetes mellitus and insulin replacement the primary therapeutic strategy. However, a lack of insulin is accompanied by disturbances in glucagon release, which is exc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20148c28840096c6f181dfbf1559521d
https://doi.org/10.1097/mco.0000000000000192
https://doi.org/10.1097/mco.0000000000000192
Autor:
Christopher R. McCartney, Paul M. Suratt, Christine Lu, Leon S. Farhy, Eleanor G Hutchens, Heather Bonner
Publikováno v:
Neuroendocrinology. 107(1)
Objective: During the early follicular phase, sleep-related luteinizing hormone (LH) pulse initiation is positively associated with brief awakenings but negatively associated with rapid eye movement (REM) sleep. The relationship between sleep archite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21164cafe3379b1ed7180ba07a4526c8
https://pubmed.ncbi.nlm.nih.gov/29506013
https://pubmed.ncbi.nlm.nih.gov/29506013
Autor:
James T. Patrie, Leon S. Farhy, Jianhua Liu, Bruce D. Gaylinn, Michael O. Thorner, Suzan S. Pezzoli, Ralf Nass
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 99:E1696-E1700
Ghrelin is a 28-amino acid peptide released from the stomach. Ghrelin is found in the circulation in two forms: acyl- and desacyl-ghrelin. Acyl- and desacyl-ghrelin concentrations increase at night, when cortisol concentrations are low. Acute ghrelin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf387772b0a5f92b526187ed94c2b903
https://doi.org/10.1210/jc.2014-1210
https://doi.org/10.1210/jc.2014-1210
Autor:
Suzan S. Pezzoli, Michael O. Thorner, Michael L. Johnson, Bruce D. Gaylinn, Leon S. Farhy, Jianhua Liu, Ralf Nass
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 99:602-608
Acyl-ghrelin is thought to have both orexigenic effects and to stimulate GH release. A possible cause of the anorexia of aging is an age-dependent decrease in circulating acyl-ghrelin levels.The purpose of the study was to compare acyl-ghrelin and GH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0c135c3aeed9e62bdc3c7dcbcbd7c5
https://doi.org/10.1210/jc.2013-3158
https://doi.org/10.1210/jc.2013-3158
Publikováno v:
Diabetes Technology & Therapeutics. 15:935-941
Insulin-induced hypoglycemia is as a critical barrier in the treatment of type 1 diabetes mellitus patients and may lead to unconsciousness, brain damage, or even death. Clinically, glucagon is used as a rescue drug to treat severe hypoglycemic episo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a0a390b5409cd3803abfa2ae9c49f4
https://doi.org/10.1089/dia.2013.0150
https://doi.org/10.1089/dia.2013.0150