Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Leon Olde Damink"'
Publikováno v:
Current Directions in Biomedical Engineering, Vol 4, Iss 1, Pp 237-241 (2018)
In this study, characteristic features of a new regenerative 3D collagen matrix with an orientated open pore structure are studied in-vitro and in-vivo. The noncrosslinked porcine-based resorbable collagen-elastin matrix is designed to provide suppor
Autor:
Marina Häcker, Vanessa Kieber, Victor Häussling, Leon Olde Damink, Andreas K. Nussler, Caren Linnemann, Sabrina Ehnert, Marc Ruoß, Helen Rinderknecht, Silas Rebholz
Publikováno v:
Methods and Protocols, Vol 3, Iss 1, p 1 (2019)
Methods and Protocols
Volume 3
Issue 1
Methods and Protocols
Volume 3
Issue 1
In order to increase the metabolic activity of human hepatocytes and liver cancer cell lines, many approaches have been reported in recent years. The metabolic activity could be increased mainly by cultivating the cells in 3D systems or co-cultures (
Autor:
Gary A. Brook, Tobias Führmann, Ingo Heschel, Leon Olde Damink, Sven Möllers, Ahmet Bozkurt, Joachim Weis, Haktan Altinova, Frank Schügner, Ronald Deumens
Publikováno v:
Brain Research. 1585:37-50
The formation of cystic cavitation following severe spinal cord injury (SCI) constitutes one of the major barriers to successful axonal regeneration and tissue repair. The development of bioengineered scaffolds that assist in the bridging of such les
Autor:
Sabrina Ehnert, Andreas K. Nussler, Serene M. L. Lee, Liming Ge, Victor Häussling, Marc Ruoß, Leon Olde Damink, Frank Schügner
Publikováno v:
Bioengineering, Vol 5, Iss 4, p 86 (2018)
Bioengineering
Volume 5
Issue 4
Bioengineering
Volume 5
Issue 4
Due to pronounced species differences, hepatotoxicity of new drugs often cannot be detected in animal studies. Alternatively, human hepatocytes could be used, but there are some limitations. The cells are not always available on demand or in sufficie
Autor:
Ahmet Bozkurt, Leon Olde Damink, Frank Schügner, Gary A. Brook, S. Möllers, Ingo Heschel, Johannes Noth, José Luis Gerardo Nava, Barbara Müller, Ronald Deumens
Publikováno v:
Tissue Engineering Part A. 15:461-472
Traumatic injury to the nervous system induces functional deficits as a result of axonal destruction and the formation of scar tissue, cystic cavitation, and physical gaps. Bioengineering bridging materials should ideally act as cell carriers for the
Autor:
Frank Schügner, Ingo Heschel, Ahmet Bozkurt, Christina Beckmann, F. Lassner, Sven Moellers, Leon Olde Damink, Michael Woeltje, Norbert Pallua, Paul Fuchs, Gary A. Brook, Joachim Weis, Julian Tank, Bernd Sellhaus
Publikováno v:
Tissue Engineering. 13:2971-2979
The goal of this study was the development of a bioartificial nerve guide to induce axonal regeneration in the peripheral nervous system (PNS). In this in vitro study, the ability of a novel, 3-dimensional (3D), highly oriented, cross-linked porcine
Autor:
Marianne E. Mertens, Josef Ehling, Fabian Kiessling, Anne Bühren, Alina Hermann, Twan Lammers, Diana Möckel, Felix Gremse, Leon Olde-Damink
Publikováno v:
Advanced functional materials, 24(6), 754-762. Wiley-VCH Verlag
Non-invasive imaging holds significant potential for implementation in tissue engineering. It can e.g. be used to monitor the localization and function of tissue-engineered implants, as well as their resorption and remodelling. Thus far, however, the
Effect of pore size and cross-linking of a novel collagen-elastin dermal substitute on wound healing
Autor:
Bouke K. H. L. Boekema, Marcel Vlig, Leon Olde Damink, Magda M. W. Ulrich, Esther Middelkoop, Anne V. Bühren, Lizette Eummelen
Publikováno v:
Boekema, B K H L, Vlig, M, Damink, L O, Middelkoop, E, Eummelen, L, Buhren, A V & Ulrich, M M W 2014, ' Effect of pore size and cross-linking of a novel collagen-elastin dermal substitute on wound healing ', Journal of Materials Science. Materials in Medicine, vol. 25, no. 2, pp. 423-433 . https://doi.org/10.1007/s10856-013-5075-2
Journal of Materials Science. Materials in Medicine, 25(2), 423-433. Springer Netherlands
Journal of Materials Science. Materials in Medicine, 25(2), 423-433. Springer Netherlands
Collagen-elastin (CE) scaffolds are frequently used for dermal replacement in the treatment of full-thickness skin defects such as burn wounds. But little is known about the optimal pore size and level of cross-linking. Different formulations of derm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a1defbe60209d5053c879b24c887e2
https://research.vumc.nl/en/publications/c01bae05-8cb4-41f9-8cbc-6c863b63acf2
https://research.vumc.nl/en/publications/c01bae05-8cb4-41f9-8cbc-6c863b63acf2
Autor:
Katrin Montzka, Leon Olde Damink, Axel Heidenreich, Joachim Grosse, Tanja Laeufer, Ingo Heschel, Sacha Tholl
Publikováno v:
Journal of Urology. 183
Autor:
Wilhelm Jahnen-Dechent, Frank Schügner, Christina Beckmann, Ingo Heschel, Bernd Sellhaus, Norbert Pallua, Joachim Weis, Gary A. Brook, Ronald Deumens, Ahmet Bozkurt, Leon Olde Damink
Publikováno v:
Biomaterials. 30(2)
Therapeutic benefits of autologous nerve grafting in repair of peripheral nerve lesions have not been reached using any alternative nerve guide. Nevertheless, issues of co-morbidity and limited availability of donor nerves urgently ask for a need of