Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Leon M J Mugenzi"'
Autor:
Leon M J Mugenzi, Theofelix A Tekoh, Stevia T Ntadoun, Achille D Chi, Mahamat Gadji, Benjamin D Menze, Magellan Tchouakui, Helen Irving, Murielle J Wondji, Gareth D Weedall, Jack Hearn, Charles S Wondji
Publikováno v:
PLoS Genetics, Vol 20, Iss 7, p e1011344 (2024)
Deciphering the evolutionary forces controlling insecticide resistance in malaria vectors remains a prerequisite to designing molecular tools to detect and assess resistance impact on control tools. Here, we demonstrate that a 4.3kb transposon-contai
Externí odkaz:
https://doaj.org/article/61b38649e8a4405aa938056bbaf281fd
Autor:
Leon M J Mugenzi, Theofelix A Tekoh, Sulaiman S Ibrahim, Abdullahi Muhammad, Mersimine Kouamo, Murielle J Wondji, Helen Irving, Jack Hearn, Charles S Wondji
Publikováno v:
PLoS Genetics, Vol 19, Iss 3, p e1010678 (2023)
Cross-resistance to insecticides in multiple resistant malaria vectors is hampering resistance management. Understanding its underlying molecular basis is critical to implementation of suitable insecticide-based interventions. Here, we established th
Externí odkaz:
https://doaj.org/article/292649815bda4bfa9c46f5e02bda0045
Autor:
Leon M. J. Mugenzi, Gabriel Akosah-Brempong, Magellan Tchouakui, Benjamin D. Menze, Theofelix A. Tekoh, Micareme Tchoupo, Francis N. Nkemngo, Murielle J. Wondji, Ekene K. Nwaefuna, Michael Osae, Charles S. Wondji
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-15 (2022)
Abstract Background Aggravation of insecticide resistance in malaria vectors is threatening the efforts to control malaria by reducing the efficacy of insecticide-based interventions hence needs to be closely monitored. This study investigated the in
Externí odkaz:
https://doaj.org/article/c608c7683f7044e29fd26eda6c505613
Autor:
Leon M. J. Mugenzi, Benjamin D. Menze, Magellan Tchouakui, Murielle J. Wondji, Helen Irving, Micareme Tchoupo, Jack Hearn, Gareth D. Weedall, Jacob M. Riveron, Charles S. Wondji
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Bed nets treated with insecticides have been instrumental in reducing malaria mortality, but insecticide resistance is on the rise. Here, Mugenzi et al. identify genetic variants in the P450 gene CYP6P9b of Anopheles funestus that associate with inse
Externí odkaz:
https://doaj.org/article/ccf4a881a06c4c60933c5e58ed594e6b
Autor:
Benjamin D. Menze, Leon M. J. Mugenzi, Magellan Tchouakui, Murielle J. Wondji, Micareme Tchoupo, Charles S. Wondji
Publikováno v:
Pathogens, Vol 11, Iss 6, p 638 (2022)
Malaria remains a major public health concern in Africa. Metabolic resistance in major malaria vectors such as An. funestus is jeopardizing the effectiveness of long-lasting insecticidal nets (LLINs) to control malaria. Here, we used experimental hut
Externí odkaz:
https://doaj.org/article/1fdcf655d1a24f4d9c23e029a02ad572
Autor:
Francis N. Nkemngo, Leon M. J. Mugenzi, Ebai Terence, Abdoulaye Niang, Murielle J. Wondji, Micareme Tchoupo, Nguiffo D. Nguete, Williams Tchapga, Helen Irving, Jacques D. M. Ntabi, Romuald Agonhossou, Terence S. Boussougou-Sambe, Romaric B. Akoton, Felix Koukouikila-Koussounda, Yudi T. Pinilla, Francine Ntoumi, Luc S. Djogbenou, Stephen M. Ghogomu, Cyrille Ndo, Ayola A. Adegnika, Steffen Borrmann, Charles S. Wondji
Publikováno v:
Wellcome Open Research, Vol 5 (2020)
Background: Reducing the burden of malaria requires better understanding of vector populations, particularly in forested regions where the incidence remains elevated. Here, we characterized malaria vectors in a locality near the Yaoundé internationa
Externí odkaz:
https://doaj.org/article/d5d7a6d90cd542f2883c4625b8727f98
Autor:
Daniel NGUIFFO-NGUETE, Leon M. J. MUGENZI, Emile Zola MANZAMBI, Magellan TCHOUAKUI, Murielle WONDJI, Theofelix TEKOH, Francis WATSENGA, Fiacre AGOSSA, charles S Wondji
Assessing patterns and evolution of insecticide resistance in malaria vectors is a prerequisite to design suitable control strategies. Here, we characterised resistance profile in Anopheles gambiae and Anopheles funestus in Kinshasa and assess the le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92b9b6812692fa39a29a8673a9166da1
https://doi.org/10.21203/rs.3.rs-2893935/v1
https://doi.org/10.21203/rs.3.rs-2893935/v1
Autor:
Fleuriane Metissa Djondji Kamga, Leon M. J. Mugenzi, Magellan Tchouakui, Maurice Marcel Sandeu, Claudine Grace Tatsinkou Maffo, Maximilienne Ascension Nyegue, Charles S. Wondji
Publikováno v:
Microorganisms
Volume 11
Issue 3
Pages: 644
Volume 11
Issue 3
Pages: 644
Microbiome composition has been associated with insecticide resistance in malaria vectors. However, the contribution of major symbionts to the increasingly reported resistance escalation remains unclear. This study explores the possible association o
Autor:
Magellan Tchouakui, Leon M. J. Mugenzi, Benjamin D. Menze, Jude N. T. Khaukha, Williams Tchapga, Micareme Tchoupo, Murielle J. Wondji, Charles S. Wondji
Publikováno v:
Pathogens, Vol 10, Iss 4, p 415 (2021)
Monitoring cases of insecticide resistance aggravation and the effect on the efficacy of control tools is crucial for successful malaria control. In this study, the resistance intensity of major malaria vectors from Uganda was characterised and its i
Externí odkaz:
https://doaj.org/article/dd3dbc210474403789eecac195bf814f
Autor:
Yvan Fotso-Toguem, Billy Tene-Fossog, Leon M. J. Mugenzi, Murielle J. Wondji, Flobert Njiokou, Hilary Ranson, Charles S. Wondji
Publikováno v:
Genes; Volume 14; Issue 1; Pages: 52
Assessing the genetic diversity of metabolic resistance genes, such as cytochrome P450s, helps to understand the dynamics and evolution of resistance in the field. Here, we analyzed the polymorphisms of CYP6M2 and CYP6P4, associated with pyrethroid r