Zobrazeno 1 - 10
of 328
pro vyhledávání: '"Leon J. Schurgers"'
Autor:
Mark M. G. Mulder, Joep Schellens, Jan-Willem E. M. Sels, Frank van Rosmalen, Anne-Marije Hulshof, Femke de Vries, Ruud Segers, Casper Mihl, Walther N. K. A. van Mook, Aalt Bast, Henri M. H. Spronk, Yvonne M. C. Henskens, Iwan C. C. van der Horst, Hugo ten Cate, Leon J. Schurgers, Marjolein Drent, Bas C. T. van Bussel
Publikováno v:
Journal of Intensive Care, Vol 11, Iss 1, Pp 1-12 (2023)
Abstract Background Extra-hepatic vitamin K-status, measured by dephosphorylated uncarboxylated matrix Gla protein (dp-ucMGP), maintains vascular health, with high levels reflecting poor vitamin K status. The occurrence of extra-hepatic vitamin K def
Externí odkaz:
https://doaj.org/article/5350234c011e4986b380f9e8c03db898
Autor:
Judith Potjewijd, Rachid Tobal, Karin A. Boomars, Vanessa V. P. M. van Empel, Femke de Vries, Jan G. M. C. Damoiseaux, Leon J. Schurgers, Pieter van Paassen
Publikováno v:
Diagnostics, Vol 13, Iss 23, p 3526 (2023)
Background: Systemic sclerosis (SSc) patients face an elevated risk of cardiovascular disease (CVD), even when classic cardiovascular risk factors are considered. Plasma dephosphorylated-uncarboxylated Matrix Gla-protein (dp-ucMGP), an inactive form
Externí odkaz:
https://doaj.org/article/93dd2551e63949b3b4e05a4200c229c8
Autor:
Berta H. Ganizada, Koen D. Reesink, Shaiv Parikh, Mitch J. F. G. Ramaekers, Asim C. Akbulut, Pepijn J. M. H. Saraber, Gijs P. Debeij, MUMC-TAA Student Team, Armand M. Jaminon, Ehsan Natour, Roberto Lorusso, Joachim E. Wildberger, Barend Mees, Geert Willem Schurink, Michael J. Jacobs, Jack Cleutjens, Ingrid Krapels, Alexander Gombert, Jos G. Maessen, Ryan Accord, Tammo Delhaas, Simon Schalla, Leon J. Schurgers, Elham Bidar
Publikováno v:
Biomedicines, Vol 11, Iss 8, p 2095 (2023)
Current management guidelines for ascending thoracic aortic aneurysms (aTAA) recommend intervention once ascending or sinus diameter reaches 5–5.5 cm or shows a growth rate of >0.5 cm/year estimated from echo/CT/MRI. However, many aTAA dissections
Externí odkaz:
https://doaj.org/article/1f27f278042346108153c2b8609e8de4
Publikováno v:
Nutrients, Vol 15, Iss 12, p 2727 (2023)
Vitamin K and vitamin K-dependent proteins have been reported to be associated with a large spectrum of age-related diseases. While most of these associations have been deduced from observational studies, solid evidence for the direct impact of vitam
Externí odkaz:
https://doaj.org/article/4e658d3f1b364864b1bf26970ed3de26
Autor:
Luise Klein, Daan R.M.G. Ophelders, Daniel van den Hove, Maurits Damoiseaux, Bart P.F. Rutten, Chris P.M. Reutelingsperger, Leon J. Schurgers, Tim G.A.M. Wolfs
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 23, Iss , Pp 100458- (2022)
Systemic and cerebral inflammation following antenatal infection (e.g. chorioamnionitis) and dysregulation of the blood brain barrier (BBB) are major risk factors for abnormal neonatal brain development. Administration of multipotent adult progenitor
Externí odkaz:
https://doaj.org/article/9013ca5b1e144f069340a48d2ed5fe67
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 4, p 1261 (2023)
Although defined by the presence of airflow obstruction and respiratory symptoms, patients with chronic obstructive pulmonary disease (COPD) are characterized by multimorbidity. Numerous co-occurring conditions and systemic manifestations contribute
Externí odkaz:
https://doaj.org/article/eabcba0193e24f4dbfd8b60da69e74e8
Autor:
Stefanos Roumeliotis, Ioannis E. Neofytou, Cecile Maassen, Petra Lux, Konstantia Kantartzi, Evangelos Papachristou, Leon J. Schurgers, Vassilios Liakopoulos
Publikováno v:
Metabolites, Vol 13, Iss 2, p 303 (2023)
We aimed to investigate the association between Red Blood Cell Distribution Width (RDW) and Neutrophil-to-Lymphocyte Ratio (NLR), simple, rapidly assessed markers from the complete blood count with vascular calcification (VC)/stiffness and cardiovasc
Externí odkaz:
https://doaj.org/article/7932341741ec46e0b7b0d2f3d2634916
Autor:
Margot P. J. Visser, Anton S. M. Dofferhoff, Jody M. W. van den Ouweland, Henny van Daal, Cornelis Kramers, Leon J. Schurgers, Rob Janssen, Jona Walk
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/1af383c7ff944e119397679399964714
Autor:
Nikolaos T. Skenteris, Till Seime, Anna Witasp, Eva Karlöf, Grzegorz B. Wasilewski, Marina A. Heuschkel, Armand M.G. Jaminon, Loureen Oduor, Robert Dzhanaev, Malin Kronqvist, Mariette Lengquist, Frederique E.C.M. Peeters, Magnus Söderberg, Rebecka Hultgren, Joy Roy, Lars Maegdefessel, Hildur Arnardottir, Eva Bengtsson, Isabel Goncalves, Thomas Quertermous, Claudia Goettsch, Peter Stenvinkel, Leon J. Schurgers, Ljubica Matic
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 2, Pp n/a-n/a (2022)
Abstract Rationale Vascular calcification is a prominent feature of late‐stage diabetes, renal and cardiovascular disease (CVD), and has been linked to adverse events. Recent studies in patients reported that plasma levels of osteomodulin (OMD), a
Externí odkaz:
https://doaj.org/article/7f1255b91c9c4ad38f68f2fed7276dc9
Autor:
Angelina Pavlic, Hessel Poelman, Grzegorz Wasilewski, Kanin Wichapong, Petra Lux, Cecile Maassen, Esther Lutgens, Leon J. Schurgers, Chris P. Reutelingsperger, Gerry A. F. Nicolaes
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2027 (2023)
Vascular calcification (VC) is an important contributor and prognostic factor in the pathogenesis of cardiovascular diseases. VC is an active process mediated by the release of extracellular vesicles by vascular smooth muscle cells (VSMCs), and the e
Externí odkaz:
https://doaj.org/article/13c3fae4fd2a4699ac409f003b14fc17