Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Leon J de Windt"'
Autor:
Megan V Cannon, Herman HW Silljé, Jürgen WA Sijbesma, Inge Vreeswijk‐Baudoin, Jolita Ciapaite, Bart van der Sluis, Jan van Deursen, Gustavo JJ Silva, Leon J de Windt, Jan‐Åke Gustafsson, Pim van der Harst, Wiek H van Gilst, Rudolf A de Boer
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 9, Pp 1229-1243 (2015)
Abstract Pathological cardiac hypertrophy is characterized by a shift in metabolic substrate utilization from fatty acids to glucose, but the molecular events underlying the metabolic remodeling remain poorly understood. Here, we investigated the rol
Externí odkaz:
https://doaj.org/article/a60b17b5ab81414fab6747461a6c56fa
Autor:
Camilla Soragni, Jana-Ch Hegenbarth, Giulia Spanò, Federica De Majo, Servé Olieslagers, Dena Esfandyari Shahvar, Malte Tiburcy, Wolfram H. Zimmermann, Monika Stoll, Leon J. De Windt
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 10, Iss , Pp 100111- (2024)
Externí odkaz:
https://doaj.org/article/106ccd7034654a3eadf175a21413f9fd
Autor:
Tim Peters, Steffie Hermans-Beijnsberger, Abdelaziz Beqqali, Nicole Bitsch, Shinichi Nakagawa, Kannanganattu V Prasanth, Leon J de Windt, Ralph J van Oort, Stephane Heymans, Blanche Schroen
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0150236 (2016)
Long non-coding RNAs (lncRNAs) are a class of RNA molecules with diverse regulatory functions during embryonic development, normal life, and disease in higher organisms. However, research on the role of lncRNAs in cardiovascular diseases and in parti
Externí odkaz:
https://doaj.org/article/03a1e7f07452424a9bf3121042eda479
Autor:
Ella M Poels, Nicole Bitsch, Jos M Slenter, M Eline Kooi, Chiel C de Theije, Leon J de Windt, Vanessa P M van Empel, Paula A da Costa Martins
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e92983 (2014)
Pulmonary hypertension and subsequent right ventricular (RV) failure are associated with high morbidity and mortality. Prognosis is determined by occurrence of RV failure. Currently, adequate treatment for RV failure is lacking. Further research into
Externí odkaz:
https://doaj.org/article/e968aad005734b4081a442f1c9d50075
Autor:
Stefanos Leptidis, Hamid El Azzouzi, Sjoukje I Lok, Roel de Weger, Servé Olieslagers, Natasja Kisters, Gustavo J Silva, Stephane Heymans, Edwin Cuppen, Eugene Berezikov, Leon J De Windt, Paula da Costa Martins
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57800 (2013)
MicroRNAs (miRNAs) are a class of non-coding RNAs of ∼22 nucleotides in length, and constitute a novel class of gene regulators by imperfect base-pairing to the 3'UTR of protein encoding messenger RNAs. Growing evidence indicates that miRNAs are im
Externí odkaz:
https://doaj.org/article/4f5e890bfdfe449ba35aa7018a154ce6
Autor:
Hamid el Azzouzi, Stefanos Leptidis, Meriem Bourajjaj, Marc van Bilsen, Paula A da Costa Martins, Leon J De Windt
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e36799 (2012)
BACKGROUND: The response of the postnatal heart to growth and stress stimuli includes activation of a network of signal transduction cascades, including the stress activated protein kinases such as p38 mitogen-activated protein kinase (MAPK), c-Jun N
Externí odkaz:
https://doaj.org/article/2160f88c15f34659b8fda4adaa398a24
Autor:
Anne-Sophie Armand, Iman Laziz, Dounia Djeghloul, Sylvie Lécolle, Anne T Bertrand, Olivier Biondi, Leon J De Windt, Christophe Chanoine
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27283 (2011)
Apoptosis Inducing Factor (AIF) is a highly conserved, ubiquitous flavoprotein localized in the mitochondrial intermembrane space. In vivo, AIF provides protection against neuronal and cardiomyocyte apoptosis induced by oxidative stress. Conversely i
Externí odkaz:
https://doaj.org/article/cd65edbb7d954aa8a79f6e7af60092b8
Autor:
Camilla Soragni, Gwenaëlle Rabussier, Henriëtte L. Lanz, Kristin M. Bircsak, Leon J. de Windt, Sebastiaan J. Trietsch, Colin E. Murdoch, Chee Ping Ng
Publikováno v:
Redox Biology, Vol 57, Iss , Pp 102488- (2022)
Reactive oxygen species (ROS) have different properties and biological functions. They contribute to cell signaling and, in excessive amounts, to oxidative stress (OS). Although ROS is pivotal in a wide number of physiological systems and pathophysio
Externí odkaz:
https://doaj.org/article/857f974442214bc5869b76984b57a033
Autor:
Andrea Raso, Ellen Dirkx, Vasco Sampaio-Pinto, Hamid el Azzouzi, Ryan J. Cubero, Daniel W. Sorensen, Lara Ottaviani, Servé Olieslagers, Manon M. Huibers, Roel de Weger, Sailay Siddiqi, Silvia Moimas, Consuelo Torrini, Lorena Zentillin, Luca Braga, Diana S. Nascimento, Paula A. da Costa Martins, Jop H. van Berlo, Serena Zacchigna, Mauro Giacca, Leon J. De Windt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/82ddc211aa884ddea4f743c7628acbd6
Autor:
Gwenaëlle Rabussier, Ivan Bünter, Josse Bouwhuis, Camilla Soragni, Torben van Zijp, Chee Ping Ng, Karel Domansky, Leon J. de Windt, Paul Vulto, Colin E. Murdoch, Kristin M. Bircsak, Henriëtte L. Lanz
Publikováno v:
Acta Biomaterialia. 164:363-376
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75df80edf422738a7e87186934b40807
https://doi.org/10.1016/j.actbio.2023.04.033
https://doi.org/10.1016/j.actbio.2023.04.033