Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Leon Hellmann"'
Autor:
Swann Gaulis, Lina Schukur, Leon Hellmann, Vanessa Cornacchione, Ulrike Naumann, Christoph Gaul, Ralph Tiedt, Francesco Hofmann, Louise Barys, Eric Billy, Elisabetta Traggiai, Sebastian Bergling, Moriko Ito, Ying Lin, Antoine de Weck, Grainne Kerr, Barbara Schacher Engstler, David A. Ruddy, Selina Jansky, Caroline Dafflon, Andreas Weiss, Frédéric Stauffer, Karen Kapur
Publikováno v:
Oncotarget
The histone 3 lysine 79 (H3K79) methyltransferase (HMT) DOT1L is known to play a critical role for growth and survival of MLL-rearranged leukemia. Serendipitous observations during high-throughput drug screens indicated that the use of DOT1L inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d34b52a22b6f0483ff80e96d4167efc
http://europepmc.org/articles/PMC7082114
http://europepmc.org/articles/PMC7082114
Autor:
Katja, Glinšek, Lovro, Kramer, Aleksander, Krajnc, Eva, Kranjc, Nina, Pirher, Jaka, Marušič, Leon, Hellmann, Barbara, Podobnik, Borut, Štrukelj, David, Ausländer, Rok, Gaber
Publikováno v:
Biotechnology Journal. 17:2100499
Difficulties in obtaining and maintaining the desired level of the critical quality attributes (CQAs) of therapeutic proteins as well as the pace of the development are major challenges of current biopharmaceutical development. Therapeutic proteins,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0827947dcd6b168365f1a153407e6a56
https://doi.org/10.1002/biot.202100499
https://doi.org/10.1002/biot.202100499
Autor:
Leon Hellmann, Leila Rachid, Simon Ausländer, Xavier Pierrat, Martin Fussenegger, David Ausländer
Publikováno v:
Nature methods. 15(1)
Synthetic biologists have advanced the design of trigger-inducible gene switches and their assembly into input-programmable circuits that enable engineered human cells to perform arithmetic calculations reminiscent of electronic circuits. By designin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ffb6a4dd4830c6981f3f6897773f35e
https://pubmed.ncbi.nlm.nih.gov/29200199
https://pubmed.ncbi.nlm.nih.gov/29200199