Zobrazeno 1 - 10 of 44 pro vyhledávání: '"Leon Coulier"'
1
Akademický článek
Interpretation and visualization of non-linear data fusion in kernel space: study on metabolomic characterization of progression of multiple sclerosis.
Autor: Agnieszka Smolinska, Lionel Blanchet, Leon Coulier, Kirsten A M Ampt, Theo Luider, Rogier Q Hintzen, Sybren S Wijmenga, Lutgarde M C Buydens
Publikováno v: PLoS ONE, Vol 7, Iss 6, p e38163 (2012)
BACKGROUND: In the last decade data fusion has become widespread in the field of metabolomics. Linear data fusion is performed most commonly. However, many data display non-linear parameter dependences. The linear methods are bound to fail in such si
Externí odkaz: https://doaj.org/article/a505c42347ac4424ba9c1f069ddc3bc2
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2
Akademický článek
Understanding and classifying metabolite space and metabolite-likeness.
Autor: Julio E Peironcely, Theo Reijmers, Leon Coulier, Andreas Bender, Thomas Hankemeier
Publikováno v: PLoS ONE, Vol 6, Iss 12, p e28966 (2011)
While the entirety of 'Chemical Space' is huge (and assumed to contain between 10(63) and 10(200) 'small molecules'), distinct subsets of this space can nonetheless be defined according to certain structural parameters. An example of such a subspace
Externí odkaz: https://doaj.org/article/b490bb06b9934b5bab93c462fb6a84a3
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3
Pre-processing liquid chromatography/high-resolution mass spectrometry data: extracting pure mass spectra by deconvolution from the invariance of isotopic distribution
Autor: Margriet M. W. B. Hendriks, Leon Coulier, Uwe Thissen, Richard C. Bas, Elwin Verheij, Shaji Krishnan, Thomas Hankemeier
Publikováno v: Rapid Communications in Mass Spectrometry. 27:917-923
RATIONALE Mass spectra obtained by deconvolution of liquid chromatography/high-resolution mass spectrometry (LC/HRMS) data can be impaired by non-informative mass-over-charge (m/z) channels. This impairment of mass spectra can have significant negati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b7044c3c953d2186fbcbc29e3e92b5ae
https://doi.org/10.1002/rcm.6517
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4
Analysis of oligosaccharides in lignocellulosic biomass hydrolysates by high-performance anion-exchange chromatography coupled with mass spectrometry (HPAEC–MS)
Autor: Peter J. Punt, Leon Coulier, Richard C. Bas, Ying Zha
Publikováno v: Bioresource Technology. 133:221-231
The carbohydrate composition of lignocellulosic biomass hydrolysates is highly complex. High performance anion exchange chromatography coupled with pulsed amperometric detection (HPAEC-PAD), a widely used method for carbohydrate analysis, provides li
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::402fde73b0c57c120545c06ed66b5cb5
https://doi.org/10.1016/j.biortech.2013.01.085
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5
Instrument and process independent binning and baseline correction methods for liquid chromatography–high resolution-mass spectrometry deconvolution
Autor: Shaji Krishnan, Uwe Thissen, Jack T. W. E. Vogels, Richard C. Bas, Leon Coulier, Thomas Hankemeier, Margriet M. W. B. Hendriks
Publikováno v: Analytica Chimica Acta. 740:12-19
Setting appropriate bin sizes to aggregate hyphenated high-resolution mass spectrometry data, belonging to similar mass over charge (m/. z) channels, is vital to metabolite quantification and further identification. In a high-resolution mass spectrom
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4673c0311edd9548fd451ba03483144
https://doi.org/10.1016/j.aca.2012.06.014
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6
Effect of bioprocessing of wheat bran in wholemeal wheat breads on the colonic SCFA production in vitro and postprandial plasma concentrations in men
Autor: Wouter H. J. Vaes, Koen Venema, Emilia Selinheimo, Robert Havenaar, Nuria Mateo Anson, Guido R.M.M. Haenen, Leon Coulier, Aalt Bast
Publikováno v: Food Chemistry, 128(2), 404-409. Elsevier Limited
Mateo Anson, N, Havenaar, R, Vaes, W, Coulier, L, Venema, K, Selinheimo, E, Bast, A & Haenen, G R M M 2011, ' Effect of bioprocessing of wheat bran in wholemeal wheat breads on the colonic SCFA production in vitro and postprandial plasma concentrations in men ', Food Chemistry, vol. 128, no. 2, pp. 404-409 . https://doi.org/10.1016/j.foodchem.2011.03.043
Food Chemistry, 2, 128, 404-409
The health benefits of whole grain consumption can be partly attributed to the inclusion of the bran or outer-layers of the grain rich in dietary fibre. Fibre is fermented in the colon, leading to the production of beneficial metabolites, such as sho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a0e62504a809556848906d5902f3584
https://cris.maastrichtuniversity.nl/en/publications/0bab474e-f651-4b1c-8bfb-4e571bb32e92
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7
A proper metabolomics strategy supports efficient food quality improvement: A case study on tomato sensory properties
Autor: Karin M. Overkamp, Jan Jetten, Bianca J. C. van der Werff, Toon van de Ven, Leon Coulier, Uwe Thissen, Mariët J. van der Werf
Publikováno v: Food Quality and Preference. 22:499-506
In agricultural and food products, typical quality parameters are sensory properties, shelf-life, safety, health, nutritional value, crop yield per area and disease resistance. It is known that these parameters are importantly determined by the metab
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::25a8546d2bd437a06649c26160c97d59
https://doi.org/10.1016/j.foodqual.2010.12.001
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8
The Impact of Delayed Storage on the Measured Proteome and Metabolome of Human Cerebrospinal Fluid
Autor: Therese Rosenling, Alain J. van Gool, Sybren S. Wijmenga, Rob J. Vreeken, Bas Muilwijk, Adrie Dane, Theo M. Luider, Lutgarde M. C. Buydens, Peter Horvatovich, Shanna Shi, Christin Christin, Agnieszka Smolinska, Marcel P. Stoop, Thomas Hankemeier, Frank Suits, Rainer Bischoff, Leon Coulier
Publikováno v: Clinical Chemistry, 57(12), 1703-1711. American Association for Clinical Chemistry Inc.
Clinical Chemistry, 57, 1703-1711
Clinical Chemistry, 57, 12, pp. 1703-11
Clinical Chemistry, 57(12), 1703-1711. AMER ASSOC CLINICAL CHEMISTRY
Clinical Chemistry, 57, 12, pp. 1703-1711
Clinical Chemistry, 57, 1703-11
Clinical Chemistry, 12, 57, 1703-1711
BACKGROUND Because cerebrospinal fluid (CSF) is in close contact with diseased areas in neurological disorders, it is an important source of material in the search for molecular biomarkers. However, sample handling for CSF collected from patients in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45f237008644d12dc3fd3a14f8fa34de
https://doi.org/10.1373/clinchem.2011.167601
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9
Quantitative Proteomics and Metabolomics Analysis of Normal Human Cerebrospinal Fluid Samples
Autor: Marcel P. Stoop, Leon Coulier, Therese Rosenling, Shanna Shi, Agnieszka M. Smolinska, Lutgarde Buydens, Kirsten Ampt, Christoph Stingl, Adrie Dane, Bas Muilwijk, Ronald L. Luitwieler, Peter A.E. Sillevis Smitt, Rogier Q. Hintzen, Rainer Bischoff, Sybren S. Wijmenga, Thomas Hankemeier, Alain J. van Gool, Theo M. Luider
Publikováno v: Molecular & Cellular Proteomics, 9, 2063-2075
Molecular & Cellular Proteomics, 9, 9, pp. 2063-2075
Molecular & Cellular Proteomics, 9(9), 2063-2075. American Society for Biochemistry and Molecular Biology Inc.
Molecular & Cellular Proteomics, 9(9), 2063-2075. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
Molecular and Cellular Proteomics, 9, 9, 2063-2075
The analysis of cerebrospinal fluid (CSF) is used in biomarker discovery studies for various neurodegenerative central nervous system (CNS) disorders. However, little is known about variation of CSF proteins and metabolites between patients without n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa1a48ca07c68ca915885fe9785baaa
https://doi.org/10.1074/mcp.m110.000877
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10
The Effect of Preanalytical Factors on Stability of the Proteome and Selected Metabolites in Cerebrospinal Fluid (CSF)
Autor: Leon Coulier, Christiaan L. Slim, Rainer Bischoff, Theo M. Luider, Marcel P. Stoop, Alain J. van Gool, Christin Christin, Rob J. Vreeken, Peter Horvatovich, Jan Bosman, Frank Suits, Therese Rosenling, Thomas Hankemeier, Norbert Stockhofe-Zurwieden, Shanna Shi
Publikováno v: Journal of Proteome Research, 8(12), 5511-5522
Journal of Proteome Research 8 (2009) 12
Journal of Proteome Research, 8(12), 5511-5522. American Chemical Society
Journal of Proteome Research, 8(12), 5511-5522. NLM (Medline)
Journal of Proteome Research, 12, 8, 5511-5522
To standardize the use of cerebrospinal fluid (CSF) for biomarker research, a set of stability studies have been performed on porcine samples to investigate the influence of common sample handling procedures on proteins, peptides, metabolites and fre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::629e77227868bba6ea772d331ca6481c
https://pure.eur.nl/en/publications/a4ea360a-2749-4437-9dd1-95c256a71b92
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