Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Leon B. Hall"'
Publikováno v:
Molecular Diversity. 5:1-5
An efficient solid phase regioselective alkylation at the N4 position of a 3-oxo-1,4-benzodiazepine template exemplified by 4-H-2,3,4,5-tetrahydro-7-iodo-3-oxo-1H-1,4-benzodiazepine-2-acetate-polymer ester is described. Further chemical elaboration a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd0aeabea39e05614882f9de09ca603c
https://doi.org/10.1023/a:1011377008730
https://doi.org/10.1023/a:1011377008730
Autor:
Richard M. Keenan, Steven T. Ross, M. Amparo Lago, S M Hwang, Eliot H. Ohlstein, Tian-Li Yue, David J. Rieman, Chet Kwon, Fadia E. Ali, Brian R. Smith, Lynne Vickery, Thomas T. Nguyen, Dalia R. Jakas, Russell D. Cousins, Calvert Louden, Jeffrey M. Stadel, Leon B. Hall, James Samanen, William H. Miller, Catherine C.K. Yuan, Dennis T. Takata
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 8:3171-3176
In the 3-oxo-1,4-benzodiazepine-2-acetic acid series of vitronectin receptor (alpha v beta 3) antagonists, a compound containing an imidazopyridine arginine mimetic was discovered which had sufficient potency and i.v. pharmacokinetics for demonstrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd994a9ec637d9aef7d70da2654228e
https://doi.org/10.1016/s0960-894x(98)00556-3
https://doi.org/10.1016/s0960-894x(98)00556-3
Autor:
Kenneth A. Newlander, Chet Kwon, William F. Huffman, Richard M. Keenan, Leon B. Hall, James Samanen, Chuan-Kui Yuan, T. W. Ku, William E. Bondinell, F. E. Ali, Karl F. Erhard, Raul R. Calvo, William H. Miller, Larry D. Davis, Dennis T. Takata, Stephen T. Ross
Publikováno v:
Tetrahedron Letters. 36:9433-9436
An enantiospecific synthesis of SB 214857, a potent, nonpeplide fibrinogen receptor antagonist, is reported. The synthetic route employs as a key step an intramolecular aryl fluoride displacement to form the sevenmembered ring of the 1,4-benzodiazepi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e020141c650769ae0d556a7deb7f5124
https://doi.org/10.1016/0040-4039(95)02054-3
https://doi.org/10.1016/0040-4039(95)02054-3