Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Leon Anavy"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Data storage in DNA has recently emerged as a promising archival solution, offering space-efficient and long-lasting digital storage solutions. Recent studies suggest leveraging the inherent redundancy of synthesis and sequencing technologie
Externí odkaz:
https://doaj.org/article/f6a312ef61324ede85c41157b2b0f6dd
Autor:
Ido Amit, Ortal Iancu, Alona Levy-Jurgenson, Gavin Kurgan, Matthew S. McNeill, Garrett R. Rettig, Daniel Allen, Dor Breier, Nimrod Ben Haim, Yu Wang, Leon Anavy, Ayal Hendel, Zohar Yakhini
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
The control of off-target activity is a challenge for adapting CRISPR to therapeutic use. Here the authors present CRISPECTOR, a software tool to detect, evaluate and quantify editing activity, including translocations, from NGS data.
Externí odkaz:
https://doaj.org/article/a5eef4e669634506b9f9db24ef9fe0fe
Autor:
Lior Levy, Leon Anavy, Oz Solomon, Roni Cohen, Michal Brunwasser-Meirom, Shilo Ohayon, Orna Atar, Sarah Goldberg, Zohar Yakhini, Roee Amit
Publikováno v:
Cell Reports, Vol 21, Iss 3, Pp 845-858 (2017)
We use an oligonucleotide library of >10,000 variants to identify an insulation mechanism encoded within a subset of σ54 promoters. Insulation manifests itself as reduced protein expression for a downstream gene that is expressed by transcriptional
Externí odkaz:
https://doaj.org/article/7d4fd9ada4074558bd5319622a2cf784
Storage needs represent a significant burden on the economy and the environment. Some of this can potentially be offset by improved density molecular storage. The potential of using DNA for storing data is immense. DNA can be harnessed as a high dens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0af2030a829b33aaeea607906a63e13
https://doi.org/10.1101/2021.08.01.454622
https://doi.org/10.1101/2021.08.01.454622
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports
Recent developments in personalized medicine are based on molecular measurement steps that guide personally adjusted medical decisions. A central approach to molecular profiling consists of measuring DNA, RNA, and/or proteins in tissue samples, most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::736650bc6832d5a89a433c22b54ad12f
http://link.springer.com/article/10.1038/s41598-019-51634-7
http://link.springer.com/article/10.1038/s41598-019-51634-7
Publikováno v:
Nature Biotechnology. 37:1229-1236
The density and long-term stability of DNA make it an appealing storage medium, particularly for long-term data archiving. Existing DNA storage technologies involve the synthesis and sequencing of multiple nominally identical molecules in parallel, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81adcc3975bfe1ed5d3561eda6d2252f
https://doi.org/10.1038/s41587-019-0240-x
https://doi.org/10.1038/s41587-019-0240-x
Autor:
Alona Levy-Jurgenson, Garrett R. Rettig, Ayal Hendel, Dor Breier, Matthew S. McNeill, Ido Amit, Zohar Yakhini, Ortal Iancu, Gavin Kurgan, Daniel Allen, Nimrod Ben Haim, Yu Wang, Leon Anavy
Publikováno v:
Nature Communication
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications
Controlling off-target editing activity is one of the central challenges in making CRISPR technology accurate and applicable in medical practice. Current algorithms for analyzing off-target activity do not provide statistical quantification, are not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6fb7f85213d21c10f4c6689fb240ab7
https://doi.org/10.1038/s41467-021-22417-4
https://doi.org/10.1038/s41467-021-22417-4
Autor:
Zohar Yakhini, Lisa Kermas, Oz Solomon, Roee Amit, Leon Anavy, Sarah Goldberg, Noa Eden, Orna Atar, Beate Kaufmann, Or Willinger
SummaryNature provides a rich toolbox of dynamic nucleic acid structures that are widespread in cells and affect multiple biological processes1. Recently, non-canonical structures gained renewed scientific and biotechnological interest2,3. One partic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75f2d26d9539fe59f09da61faf312fce