Investigation of trypanothione reductase inhibitory activity by 1,3,4-thiadiazolium-2-aminide derivatives and molecular docking studies

Autor: Rodrigues, Raquel F., Castro-Pinto, Denise, Echevarria, Aurea, dos Reis, Camilla M., Del Cistia, Catarina N., Sant’Anna, Carlos Mauricio R., Teixeira, Filipa, Castro, Helena, Canto-Cavalheiro, Marilene, Leon, Leonor L., Tomás, Ana

Publikováno v: In Bioorganic & Medicinal Chemistry 1 March 2012 20(5):1760-1766

Effectiveness of Novel 5-(5-amino-1-aryl-1 H-pyrazol-4-yl)-1 H-tetrazole Derivatives Against Promastigotes and Amastigotes of Leishmania amazonensis.

Autor: dos Santos Faiões, Viviane¹, Leon, Leonor L.¹, Canto ‐ Cavalheiro, Marilene M.¹, Torres ‐ Santos, Eduardo C.¹, Bernardino, Alice M. R.², Vegi, Percilene F.², dos Santos, Maurício S.³

Publikováno v: Chemical Biology & Drug Design. Mar2014, Vol. 83 Issue 3, p272-277. 6p.

Synthesis and in vitro evaluation of new benzenesulfonamides as antileishmanial agents

Autor: Borges,Julio C., Carvalho,Adriana V., Bernardino,Alice M. R., Oliveira,César D., Pinheiro,Luiz C. S., Marra,Roberta K. F., Castro,Helena C., Wardell,Solange M. S. V., Wardell,James L., Amaral,Veronica F., Canto-Cavalheiro,Marilene M., Leon,Leonor L., Genestra,Marcelo

Publikováno v: Journal of the Brazilian Chemical Society, Volume: 25, Issue: 5, Pages: 980-986, Published: MAY 2014
Journal of the Brazilian Chemical Society v.25 n.5 2014
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ

This paper describes the synthesis and the antileishmanial activity of new pyrazolyl benzenesulfonamide derivatives. These were elucidated by spectrometric methods. Some compounds showed a significant in vitro activity against Leishmania amazonensis,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::85965a78d5e045cecbd05be211a6b33d
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532014000500023&lng=en&tlng=en

Synthesis and activity of novel tetrazole compounds and their pyrazole-4-carbonitrile precursors against Leishmania spp

Autor: Faria, Jéssica V., dos Santos, Maurício S., Bernardino, Alice M.R., Becker, Klaus M., Machado, Gérzia M.C., Rodrigues, Raquel F., Canto-Cavalheiro, Marilene M., Leon, Leonor L.

Publikováno v: In Bioorganic & Medicinal Chemistry Letters 1 December 2013 23(23):6310-6312

Synthesis and antileishmanial activity of new 1-aryl-1H-pyrazole-4-carboximidamides derivatives

Autor: Santos, Maurício S. dos, Gomes, Adriana O, Bernardino, Alice M. R, Souza, Marcos C. de, Khan, Misbahul A, Brito, Monique A. de, Castro, Helena C, Abreu, Paula A, Rodrigues, Carlos R, Léo, Rosa M. M. de, Leon, Leonor L, Canto-Cavalheiro, Marilene M

Publikováno v: Journal of the Brazilian Chemical Society, Volume: 22, Issue: 2, Pages: 352-358, Published: FEB 2011

Chemotherapy for leishmaniasis, diseases caused by protozoa of the genus Leishmania, remains inefficient in several treatments. So there is a need to search for new drugs. In this work, we have synthesized 1-aryl-1H-pyrazole-4-carboximidamides deriva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______608::13897fab301c5099b5b3fa85e248613d
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532011000200022&lng=en&tlng=en