Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Leomar Y, Ballester"'
Autor:
Chandra Sekhar Amara, Karthik Reddy Kami Reddy, Yang Yuntao, Yuen San Chan, Danthasinghe Waduge Badrajee Piyarathna, Lacey Elizabeth Dobrolecki, David J. H. Shih, Zhongcheng Shi, Jun Xu, Shixia Huang, Matthew J. Ellis, Andrea B. Apolo, Leomar Y. Ballester, Jianjun Gao, Donna E. Hansel, Yair Lotan, H. Courtney Hodges, Seth P. Lerner, Chad J. Creighton, Arun Sreekumar, W. Jim Zheng, Pavlos Msaouel, Shyam M. Kavuri, Nagireddy Putluri
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract SMARCB1 loss has long been observed in many solid tumors. However, there is a need to elucidate targetable pathways driving growth and metastasis in SMARCB1-deficient tumors. Here, we demonstrate that SMARCB1 deficiency, defined as genomic S
Externí odkaz:
https://doaj.org/article/92dacc4a9b18472087b40b7343faadf4
Autor:
Daniel H. Wang, Yoko Fujita, Antonio Dono, Ana G. Rodriguez Armendariz, Mauli Shah, Nagireddy Putluri, Pavel S. Pichardo-Rojas, Chirag B. Patel, Jay-Jiguang Zhu, Jason T. Huse, Brittany C. Parker Kerrigan, Frederick F. Lang, Yoshua Esquenazi, Leomar Y. Ballester
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-13 (2024)
Abstract Cerebrospinal fluid (CSF) analysis is underutilized in patients with glioblastoma (GBM), partly due to a lack of studies demonstrating the clinical utility of CSF biomarkers. While some studies show the utility of CSF cell-free DNA analysis,
Externí odkaz:
https://doaj.org/article/f82f5120ed804f83a99b54df035f690c
Autor:
Ali S. Haider, Chibawanye I. Ene, Paolo Palmisciano, Maryam Haider, Ganesh Rao, Leomar Y. Ballester, Gregory N. Fuller
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Isocitrate dehydrogenase (IDH) mutations are cornerstone diagnostic features in glioma classification. IDH mutations are typically characterized by mutually exclusive amino acid substitutions in the genes encoding for the IDH1 and the IDH2 enzyme iso
Externí odkaz:
https://doaj.org/article/0fb10a28bd514956812eba548356fd1e
Autor:
Timothy P. DiPeri, Mehmet Demirhan, Daniel D. Karp, Siqing Fu, David S. Hong, Vivek Subbiah, Joann Lim, Leomar Y. Ballester, Jean H. Tayar, Maria E. Suarez-Almazor, Milind Javle, Funda Meric-Bernstam
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Pp 26-30 (2022)
Intrahepatic cholangiocarcinoma is a rare malignancy, which is rich in actionable alterations. Genomic aberrations in the mitogen-activated protein kinase (MAPK) pathway are common, and BRAF exon 15 p.V600E mutations are present in 5–7% of biliary
Externí odkaz:
https://doaj.org/article/be1451dee7c448a48031e47750b7ece3
Autor:
Arun Rajan, Christopher R. Heery, Anish Thomas, Andrew L. Mammen, Susan Perry, Geraldine O’Sullivan Coyne, Udayan Guha, Arlene Berman, Eva Szabo, Ravi A. Madan, Leomar Y. Ballester, Stefania Pittaluga, Renee N. Donahue, Yo-Ting Tsai, Lauren M. Lepone, Kevin Chin, Fiona Ginty, Anup Sood, Stephen M. Hewitt, Jeffrey Schlom, Raffit Hassan, James L. Gulley
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-12 (2019)
Abstract Background Thymic epithelial tumors are PD-L1–expressing tumors of thymic epithelial origin characterized by varying degrees of lymphocytic infiltration and a predisposition towards development of paraneoplastic autoimmunity. PD-1–target
Externí odkaz:
https://doaj.org/article/b66a3a1a163041f19fe2d792850a4a64
Autor:
Leomar Y. Ballester, Soheil Zorofchian Moghadamtousi, Norman E. Leeds, Jason T. Huse, Gregory N. Fuller
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-4 (2019)
Externí odkaz:
https://doaj.org/article/64382a27026242a0803455d4c33a6f95
Autor:
Bangxing Hong, Kamaldeen Muili, Chelsea Bolyard, Luke Russell, Tae Jin Lee, Yeshavanth Banasavadi-Siddegowda, Ji Young Yoo, Yuanqing Yan, Leomar Y. Ballester, Kurt H. Bockhorst, Balveen Kaur
Publikováno v:
Molecular Therapy: Oncolytics, Vol 12, Iss , Pp 93-102 (2019)
HMGB1 is a ubiquitously expressed intracellular protein that binds DNA and transcription factors and regulates chromosomal structure and function. Under conditions of cell death or stress, it is actively or passively released by cells into the extrac
Externí odkaz:
https://doaj.org/article/185c5a6fa40c4a3782fdededeedc9563
Autor:
Antonio Dono, Ali M. Moosvi, Puneetha S. Goli, Allison C. Bellman, Phyu P. Aung, Yoshua Esquenazi, Leomar Y. Ballester
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology. 31:288-294
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::141ab1a728c8413fcb8e47c996eaede0
https://doi.org/10.1097/pai.0000000000001118
https://doi.org/10.1097/pai.0000000000001118
Autor:
Antonio, Dono, Hanadi, El Achi, Bethany E, Bundrant, Puneetha S, Goli, Ping, Zhu, Hanim I, Ozkizilkaya, Yoshua, Esquenazi, Leomar Y, Ballester
Publikováno v:
Cancer Biomarkers. 36:117-131
BACKGROUND: Fibroblast growth factor receptors (FGFRs) are frequently altered in cancers and present a potential therapeutic avenue. However, the type and prevalence of FGFR alterations in infiltrating gliomas (IGs) needs further investigation. OBJEC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecaf0e50de72fbcc2d3facfadca06f46
https://doi.org/10.3233/cbm-220041
https://doi.org/10.3233/cbm-220041
Autor:
Antonio Dono, Anthony Patrizz, Ryan M McCormack, Nagireddy Putluri, Bhanu P Ganesh, Balveen Kaur, Louise D McCullough, Leomar Y Ballester, Yoshua Esquenazi
Publikováno v:
CNS Oncology, Vol 9, Iss 2 (2020)
Aim: To explore fecal short-chain fatty acids and neurotransmitter alterations in a mouse–glioma model and glioma patients. Methods: Liquid chromatography–mass spectrometry and 16S rRNA-sequencing from fecal samples were performed to measure meta
Externí odkaz:
https://doaj.org/article/5a2fe6d5db054f9eafcf5f508d4d8556