Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Leo Van den Bergh"'
Autor:
Anna Tivesten, Nadim Akhtar, Thomas Eichinger, Achim Geiser, Jessica A. Stolee, Tobias Metzenthin, Rachel Orr, Hill Malcolm Leithhead, Yannick Fillon, Tom Huybrechts, Leo Van den Bergh, John H. A. Amery, Andrea Brecht, Paul McCormac, Jale Muslehiddinoglu
Publikováno v:
Therapeutic Innovation & Regulatory Science. 52:687-688
A consortium of seven pharma companies has been formed with the aim of sharing knowledge on and harmonizing approaches to oligonucleotide development. This letter aims to raise awareness of this new group and to set expectations for future publicatio
Publikováno v:
Organic Process Research & Development. 12:96-100
The titanocene-catalyzed reduction of the lactone 1 into the lactol 2 was studied. This process uses poly(methylhydrosiloxane) as stoichiometric reductant. Thermodynamic and safety data was collected in order to develop a reliable, safe and scalable
Autor:
Rudy Laurent Maria Broeckx, Annemie Lambrechts, Fred Stappers, Jos Agten, Leo Van den Bergh, Dirk Van Den Heuvel, Stef Leurs, Dirk De Smaele
Publikováno v:
Organic Process Research & Development. 6:911-914
The stepwise optimization towards a safe, reproducible, and high-yielding oxidation of azepine 2 into the prochiral nitrone 4 is described, with emphasis on the elimination of Davis reagent 3. m-Chloroperoxybenzoic acid (mCPBA) was found to be an ele
Publikováno v:
Organic Process Research & Development; Dec2007, Vol. 12 Issue 1, p96-100, 5p