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pro vyhledávání: '"Leo V. Arzu"'
Autor:
Petr Hruz, Yukiko Miyamoto, Diane Smith, Leo V. Arzu, Lars Eckmann, Valery V. Fokin, Carlos A. Valdez, K. Kangas, Peter Upcroft, Yolanda S. Andersen, Jacqueline A. Upcroft, K. Barry Sharpless, Sabrina E. Brown, Barbara J. Davids, Jonathan C. Tripp, Jaroslaw Kalisiak, Frances D. Gillin
Publikováno v:
Journal of Medicinal Chemistry. 52:4038-4053
Infections with the diarrheagenic pathogen, Giardia lamblia, are commonly treated with the 5-nitroimidazole (5-NI) metronidazole (Mz), and yet treatment failures and Mz resistance occur. Using a panel of new 2-ethenyl and 2-ethanyl 5-NI derivatives,