Surfing motility is a complex adaptation dependent on the stringent stress response in Pseudomonas aeruginosa LESB58.

Autor: Daniel Pletzer, Evelyn Sun, Caleb Ritchie, Lauren Wilkinson, Leo T Liu, Michael J Trimble, Heidi Wolfmeier, Travis M Blimkie, Robert E W Hancock

Publikováno v: PLoS Pathogens, Vol 16, Iss 3, p e1008444 (2020)

Cystic fibrosis (CF) is a genetic disease that affects mucin-producing body organs such as the lungs. Characteristic of CF is the production of thick, viscous mucus, containing the glycoprotein mucin, that can lead to progressive airway obstruction.

Externí odkaz: https://doaj.org/article/d88ada66a6684776984907b7e6f26fb8

Targeting the

Autor: Heidi, Wolfmeier, Samuel J T, Wardell, Leo T, Liu, Reza, Falsafi, Annette, Draeger, Eduard B, Babiychuk, Daniel, Pletzer, Robert E W, Hancock

Publikováno v: Frontiers in microbiology. 13

Engineered liposomes composed of the naturally occurring lipids sphingomyelin (Sm) and cholesterol (Ch) have been demonstrated to efficiently neutralize toxins secreted by Gram-positive bacteria such as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::62e147cb5c161053b39650453ad72a86
https://pubmed.ncbi.nlm.nih.gov/35369481

Selection of M

Autor: Somdeb, Paul, Antonio A W L, Wong, Leo T, Liu, David M, Perrin

Publikováno v: Chembiochem : a European journal of chemical biology. 23(5)

Sequence-specific cleavage of RNA by nucleic acid catalysts in the absence of a divalent metal cation (M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::741339bf28d1d8b0f48e122e60f4d64e
https://pubmed.ncbi.nlm.nih.gov/34881502

Liposomal Therapy Attenuates Dermonecrosis Induced by Community-Associated Methicillin-Resistant Staphylococcus aureus by Targeting α-Type Phenol-Soluble Modulins and α-Hemolysin

Autor: Leo T. Liu, Heidi Wolfmeier, Sarah C. Mansour, Robert E. W. Hancock, Daniel Pletzer, Eduard B. Babiychuk, Annette Draeger

Publikováno v: Wolfmeier, Heidi Annemarie; Mansour, Sarah C; Liu, Leo T; Pletzer, Daniel; Draeger, Annette; Babiychuk, Eduard; Hancock, Robert E W (2018). Liposomal Therapy Attenuates Dermonecrosis Induced by Community-Associated Methicillin-Resistant Staphylococcus aureus by Targeting α-Type Phenol-Soluble Modulins and α-Hemolysin. EBioMedicine, 33, pp. 211-217. Elsevier 10.1016/j.ebiom.2018.06.016
EBioMedicine
EBioMedicine, Vol 33, Iss, Pp 211-217 (2018)

Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA), typified by the pulse-field type USA300, is an emerging endemic pathogen that is spreading rapidly among healthy people. CA-MRSA causes skin and soft tissue infections, life-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee729571002907506edd1bcdaea15df6
https://doi.org/10.1016/j.ebiom.2018.06.016

Targeting the Pseudomonas aeruginosa Virulence Factor Phospholipase C With Engineered Liposomes.

Autor: Wolfmeier, Heidi, Wardell, Samuel J. T., Liu, Leo T., Falsafi, Reza, Draeger, Annette, Babiychuk, Eduard B., Pletzer, Daniel, Hancock, Robert E. W.

Publikováno v: Frontiers in Microbiology; 3/18/2022, Vol. 13, p1-11, 11p