Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Leo Q. Wan"'
Publikováno v:
APL Bioengineering, Vol 8, Iss 1, Pp 016119-016119-12 (2024)
Cell chirality is crucial for the chiral morphogenesis of biological tissues, yet its underlying mechanism remains unclear. Cell organelle polarization along multiple axes in a cell body, namely, apical–basal, front–rear, and left–right, is kno
Externí odkaz:
https://doaj.org/article/ed0b08904c40490bb6470f91d923672b
Publikováno v:
APL Bioengineering, Vol 6, Iss 4, Pp 046107-046107-10 (2022)
Endothelial cells (ECs) possess a strong intrinsic clockwise (CW, or rightward) chirality under normal conditions. Enervating this chirality of ECs significantly impairs the function of the endothelial barrier. Malignant tumor cells (TCs) undergo met
Externí odkaz:
https://doaj.org/article/26e5d5bcf9964faf956dae0e096743d0
Publikováno v:
Communicative & Integrative Biology, Vol 12, Iss 1, Pp 78-81 (2019)
The maintenance of tight endothelial junctions requires the establishment of proper cell polarity, which includes not only the apicobasal and front-rear polarity but also the left-right (L-R) polarity. The cell possesses an intrinsic mechanism of ori
Externí odkaz:
https://doaj.org/article/d8433d05f3a74d7e9406f7c434967489
Publikováno v:
APL Bioengineering, Vol 4, Iss 3, Pp 031503-031503-9 (2020)
The cardiovascular system demonstrates left-right (LR) asymmetry: most notably, the LR asymmetric looping of the bilaterally symmetric linear heart tube. Similarly, the orientation of the aortic arch is asymmetric as well. Perturbations to the asymme
Externí odkaz:
https://doaj.org/article/2795d32108f34c92b3464c21031326c4
Publikováno v:
Stem Cells International, Vol 2018 (2018)
Left-right symmetry breaking is a complex developmental process and an important part of embryonic axis development. As of yet, the biophysical mechanism behind LR asymmetry establishment remains elusive for the overall asymmetry of embryos as well a
Externí odkaz:
https://doaj.org/article/7822818caaf040ab83be425658cb1cda
Autor:
Timothy P. Martens M.D., Amandine F. G. Godier, Jonathan J. Parks, Leo Q. Wan, Michael S. Koeckert, George M. Eng, Barry I. Hudson, Warren Sherman, Gordana Vunjak-Novakovic Ph.D.
Publikováno v:
Cell Transplantation, Vol 18 (2009)
Heart disease is the leading cause of death in the US. Following an acute myocardial infarction, a fibrous, noncontractile scar develops, and results in congestive heart failure in more than 500,000 patients in the US each year. Muscle regeneration a
Externí odkaz:
https://doaj.org/article/23aa0e4e74fd42e787bed08bc64d1dde
Publikováno v:
Cellular and Molecular Bioengineering
In January of 2020, the Biomedical Engineering Society (BMES)- Cellular and Molecular Bioengineering (CMBE) conference was held in Puerto Rico and themed “Vision 2020: Emerging Technologies to Elucidate the Rule of Life.” The annual BME-CMBE conf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8f6b54a46d76bb97d485682ddb5e91
https://doi.org/10.1007/s12195-021-00676-x
https://doi.org/10.1007/s12195-021-00676-x
Publikováno v:
Cell Mol Bioeng
INTRODUCTION: Cell chirality is an intrinsic cellular property that determines the directionality of cellular polarization along the left–right axis. We recently show that endothelial cell chirality can influence intercellular junction formation an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63fdc0c96be2f4e79349412e28698e33
https://doi.org/10.1007/s12195-021-00669-w
https://doi.org/10.1007/s12195-021-00669-w
Publikováno v:
J Vis Exp
Chirality is an intrinsic cellular property, which depicts the asymmetry in terms of polarization along the left-right axis of the cell. As this unique property attracts increasing attention due to its important roles in both development and disease,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afe1ce8609c011c0699749b9ff6292c6
https://pubmed.ncbi.nlm.nih.gov/35343954
https://pubmed.ncbi.nlm.nih.gov/35343954
Autor:
Tasnif Rahman, Leo Q. Wan
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::990628cfd906f22bcc698664f7d1475d
https://doi.org/10.2139/ssrn.4052248
https://doi.org/10.2139/ssrn.4052248