Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Leo Pavliv"'
Autor:
James D. West, Cristi L. Galindo, Kyungsoo Kim, John Jonghyun Shin, James B. Atkinson, Ines Macias‐Perez, Leo Pavliv, Bjorn C. Knollmann, Jonathan H. Soslow, Larry W. Markham, Erica J. Carrier
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 21 (2019)
Background Muscular dystrophy (MD) causes a progressive cardiomyopathy characterized by diffuse fibrosis, arrhythmia, heart failure, and early death. Activation of the thromboxane‐prostanoid receptor (TPr) increases calcium transients in cardiomyoc
Externí odkaz:
https://doaj.org/article/95214a90e2ad4dbbb0a6b21eedf73060
Autor:
Shahid M Nimjee, Debra Wheeler, Stacy Nelson, Richard J Shea, Taegen Sullivan, Christina Mayer, Leo Pavliv, Juliana M Layzer, Jason Lickliter, Bruce Sullenger, Bruce Campbell, Richard C Becker
Publikováno v:
Stroke. 54
Introduction: Von Willebrand Factor (VWF) is a ubiquitous component of thrombi extracted by endovascular thrombectomy from patients with large vessel occlusion (LVO) stroke. BB-031 is a modified RNA aptamer that targets von Willebrand Factor (VWF) th
Autor:
Ines Macias-Perez, Vivian Lerner, Russell Weisz, Ivan Puente, Maggie Crawford, Alexander A Fokin, Leo Pavliv, Amy Flynt
Publikováno v:
Journal of Orthopaedic Trauma
Supplemental Digital Content is Available in the Text.
Objectives: To evaluate the efficacy of intravenous (IV) ibuprofen (Caldolor) administration in the management of acute pain in orthopedic trauma patients and to minimize opioid use. Design:
Objectives: To evaluate the efficacy of intravenous (IV) ibuprofen (Caldolor) administration in the management of acute pain in orthopedic trauma patients and to minimize opioid use. Design:
Autor:
John Jonghyun Shin, Kyungsoo Kim, James West, Bjorn C. Knollmann, James B. Atkinson, Leo Pavliv, Jonathan H. Soslow, Cristi L. Galindo, Larry W. Markham, Ines Macias-Perez, Erica J. Carrier
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Muscular dystrophy ( MD ) causes a progressive cardiomyopathy characterized by diffuse fibrosis, arrhythmia, heart failure, and early death. Activation of the thromboxane‐prostanoid receptor ( TP r) increases calcium transients in cardio
Autor:
Byron Kaelin, Leo Pavliv, Ines Macias-Perez, Richard C. Dart, Kim Dalhoff, Lars E. Schmidt, Tonny Studsgaard Petersen, Ditlev N Rasmussen
Publikováno v:
Clinical Toxicology. 56:1128-1134
Context: The intravenous (IV) N-acetylcysteine (NAC) regimen used worldwide in paracetamol overdose is complex with three separate weight-based doses and is associated with a high incidence of adverse events including non-allergic anaphylactoid react
Publikováno v:
Drug Design, Development and Therapy
Thomas Marbury,1 Jerry Fox,2 Byron Kaelin,2 Leo Pavliv2 1Orlando Clinical Research Center, Inc., Orlando, FL, 2Department of Research and Development, Cumberland Pharmaceuticals, Inc., Nashville, TN, USA Purpose: Conivaptan is an intravenous dual V1A
Publikováno v:
Pulmonary Circulation. 6:211-223
Right ventricular (RV) failure is the primary cause of death in pulmonary arterial hypertension (PAH) and is a significant cause of morbidity and mortality in other forms of pulmonary hypertension. There are no approved therapies directed at preservi
Autor:
Kyungsoo Kim, Erica J. Carrier, James West, Jonghyun J Shin, Leo Pavliv, Larry W Markham, Ines Macias-Perez, Jonathan H. Soslow, Bjorn C. Knollmann, Cristi L. Galindo
Publikováno v:
Circulation Research. 123
Muscular dystrophy causes mechanical damage and increased membrane permeability of cardiomyocytes, leading to progressive cardiomyopathy and diffuse myocardial fibrosis that typically begins in the free wall of the LV. Cardiac dysfunction is a primar
Publikováno v:
Pain Practice. 11:23-32
Background: Ibuprofen and other nonsteroidal anti-inflammatory drugs are widely used to block pain and inflammation in a variety of settings. Contrarily, opioid analgesia does not block the inflammatory component of pain and the use of these agents c
Publikováno v:
American Journal of Health-System Pharmacy. 68:47-51
Purpose The pharmacokinetics, safety, and tolerability of a rapid infusion of i.v. ibuprofen in healthy adults were evaluated. Methods In this randomized, double-blind, placebo-controlled, single-dose, crossover study, 12 healthy subjects age 18–65