Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Leo M. Albert"'
Autor:
Leo M. Albert, James C. Keith, Kathleen M. Shields, Vasu Maganti, George P. Vlasuk, Jeffrey L. Feldman, Gustave T. Hebert, Debra D. Pittman, Heather H. Shih, Anthony Wong, Janet E. Paulsen, Aaron Winkler, Christine Resmini, Valerie Clerin, Nanhua Deng
Publikováno v:
Atherosclerosis. 201:53-66
Objective The present study was conducted to characterize the expression of the cysteine protease legumain in murine and human atherosclerotic tissues, and to explore the molecular mechanisms by which legumain may contribute to the pathophysiology of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de79f0d454c897c1aff6db80aae92f23
https://doi.org/10.1016/j.atherosclerosis.2008.01.016
https://doi.org/10.1016/j.atherosclerosis.2008.01.016
Autor:
Irma Isordia-Salas, Robert W. Colman, Leo M. Albert, Yelena Leathurby, Robin A. Pixley, James C. Keith, Irma M. Sainz
Publikováno v:
Arthritis Research & Therapy
The human leukocyte antigen B27 (HLA-B27) transgenic rat is a model of human inflammatory bowel disease, rheumatoid arthritis and psoriasis. Studies of chronic inflammation in other rat models have demonstrated activation of the kallikrein–kinin sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb782cdde112e3090e436904f5b373f3
http://europepmc.org/articles/PMC1175023
http://europepmc.org/articles/PMC1175023
Autor:
Leo M. Albert, Yelena Leathurby, Lili Wang, Max Follettie, Lisa Borges-Marcucci, Robert John Steffan, James C. Keith, Christopher C. Chadwick, Douglas C. Harnish
Publikováno v:
Arthritis Research & Therapy
Rheumatoid arthritis (RA) is a chronic inflammatory disease that produces synovial proliferation and joint erosions. The pathologic lesions of RA are driven through the production of inflammatory mediators in the synovium mediated, in part, by the tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e1511545e006dd12d5076b8eb90120
http://europepmc.org/articles/PMC1174937
http://europepmc.org/articles/PMC1174937
Autor:
Leo M. Albert, Chih-Ming Leo Tseng, Andrew J. Dorner, Page Bouchard, Ron L. Peterson, James C. Keith, Soo-Peang Khor
Publikováno v:
Pharmaceutical Research. 17:482-485
Recently, rhIL-11 was developed as an enteric-coated In Vivo Absorption Properties of multiparticulate formulation for oral dosing of patients with Orally Administered Recombinant inflammatory bowel disease. Therefore, we conducted a series of PK stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7771ad91a40545009523588ef2a4c03d
https://doi.org/10.1023/a:1007545524408
https://doi.org/10.1023/a:1007545524408
Autor:
Yelena Leathurby, Lisa Borges-Marcucci, Leo M. Albert, Eugene John Trybulski, Douglas C. Harnish, Susan Chippari, Amy Eckert, Richard C. Winneker, Edward Martin Matelan, Robert John Steffan, James C. Keith, Ramesh A. Bhat, Christopher C. Chadwick, Mark A. Ashwell, Steven J. Adelman, Heather A. Harris
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 102(7)
Inflammation is now recognized as a key component in a number of diseases such as atherosclerosis, rheumatoid arthritis, and inflammatory bowel disease. The transcription factor NF-κB has been shown to be involved in both the early and late stages o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f1222dc19ec706417a2c4f97b23106
https://pubmed.ncbi.nlm.nih.gov/15699342
https://pubmed.ncbi.nlm.nih.gov/15699342
Autor:
Yelena Leathurby, Ruth A. Henderson, Yogendra P. Kharode, Michael S. Malamas, James Marzolf, Richard C. Winneker, Yuan Zhu, Barry S. Komm, Richard Eric Mewshaw, Chris P. Miller, Heather A. Harris, Donald E. Frail, Leo M. Albert, James C. Keith
Publikováno v:
Endocrinology. 144(10)
The discovery of a second estrogen receptor (ER), called ERβ, in 1996 sparked intense interest within the scientific community to discover its role in mediating estrogen action. However, despite more than 6 yr of research into the function of this r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef20662dd6fa406b9313309d6822a06
https://pubmed.ncbi.nlm.nih.gov/14500558
https://pubmed.ncbi.nlm.nih.gov/14500558
Autor:
Douglas C. Harnish, Leo M. Albert, James C. Keith, Agnes Ciarletta, Amy Eckert, Marion Kasaian, Yelena Leathurby
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 286(1)
A well-established model of bowel inflammation is the HLA-B27 transgenic rat that exhibits a spontaneous disease phenotype resulting in chronic diarrhea caused by immune cell activation. Estrogens have previously been shown to modulate the immune sys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4af3a99a90bf69a3a2904407636e62ef
https://pubmed.ncbi.nlm.nih.gov/12958017
https://pubmed.ncbi.nlm.nih.gov/12958017
Publikováno v:
Cytokine. 12(12)
Recombinant human interleukin 11 (rhIL-11) is a multifunctional cytokine with immunomodulatory activity on both T cells and macrophages. The effects of rhIL-11 in a murine model of contact hypersensitivity (CHS) response have been studied. The CHS re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4b7707498cff94258643ebe0f8ad61a
https://pubmed.ncbi.nlm.nih.gov/11097746
https://pubmed.ncbi.nlm.nih.gov/11097746
Autor:
Leo M. Albert, Irma M. Sainz, James C. Keith, Robert W. Colman, Robin A. Pixley, Yelena Leatherby, Irma Isordia-Salas
Publikováno v:
Blood. 104:3437-3437
The HLA-B27 rat is a well-characterized model of human bowel disease, rheumatoid arthritis and psoriasis. Previous studies of chronic inflammation in other rat models of inflammatory disease have demonstrated activation of the kallilrein-kinin system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab5a100b0393488d3cc8605a137a5193
https://doi.org/10.1182/blood.v104.11.3437.3437
https://doi.org/10.1182/blood.v104.11.3437.3437
Autor:
Erik Marchese, Ron L. Peterson, James C. Keith, Leo M. Albert, Robert G. Schaub, Soo Peang Khor, Kyle P. McCarthy, Andrew J. Domer, Leo C-M Tseng
Publikováno v:
Gastroenterology. 118:A701
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e724732037445d069c82acc89ed061c7
https://doi.org/10.1016/s0016-5085(00)84936-7
https://doi.org/10.1016/s0016-5085(00)84936-7