Zobrazeno 1 - 10
of 195
pro vyhledávání: '"Leo M. A. Heunks"'
Autor:
Siebe G. Blok, Amne Mousa, Michelle G. Brouwer, Harm-Jan de Grooth, Ary Serpa Neto, Michiel J. Blans, Sylvia den Boer, Tom Dormans, Henrik Endeman, Timo Roeleveld, Harm Scholten, Eline R. van Slobbe-Bijlsma, Erik Scholten, Hugo Touw, Fleur Stefanie L. I. M. van der Ven, Evert-Jan Wils, David J. van Westerloo, Leo M. A. Heunks, Marcus J. Schultz, Frederique Paulus, Pieter R. Tuinman
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-11 (2023)
Abstract Background Fluid therapy is a common intervention in critically ill patients. It is increasingly recognised that deresuscitation is an essential part of fluid therapy and delayed deresuscitation is associated with longer invasive ventilation
Externí odkaz:
https://doaj.org/article/0c4fa15535a041d7b236f435619001f8
Autor:
Alexander P. J. Vlaar, Endry H. T. Lim, Sanne deBruin, Simon Rückinger, Korinna Pilz, Matthijs C. Brouwer, Ren‐Feng Guo, Leo M. A. Heunks, Matthias H. Busch, Pieter vanPaassen, Niels C. Riedemann, Diederik van deBeek
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 4, Pp 854-858 (2022)
Abstract Recently, we reported the phase II portion of the adaptive phase II/III PANAMO trial exploring potential benefit and safety of selectively blocking C5a with the monoclonal antibody vilobelimab (IFX‐1) in patients with severe coronavirus di
Externí odkaz:
https://doaj.org/article/9ac0c341bdd04701b82fba38b9b0a290
Autor:
Micah L. A. Heldeweg, Lian Vermue, Max Kant, Michelle Brouwer, Armand R. J. Girbes, Mark E. Haaksma, Leo M. A. Heunks, Amne Mousa, Jasper M. Smit, Thomas W. Smits, Frederique Paulus, Johannes C. F. Ket, Marcus J. Schultz, Pieter Roel Tuinman
Publikováno v:
The Ultrasound Journal, Vol 14, Iss 1, Pp 1-8 (2022)
Abstract Background Lung ultrasound has established itself as an accurate diagnostic tool in different clinical settings. However, its effects on clinical-decision making are insufficiently described. This systematic review aims to investigate the im
Externí odkaz:
https://doaj.org/article/d32da65969ad44cda6dc40cb1f13cda1
Autor:
Johanna P. van Gemert, Inge A. H. van den Berk, Esther J. Nossent, Leo M. A. Heunks, Rene E. Jonkers, Alexander P. Vlaar, Peter I. Bonta
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Treatment for interstitial lung disease (ILD) patients with acute respiratory failure (ARF) is challenging, and literature to guide such treatment is scarce. The reported in-hospital mortality rates of ILD patients with ARF are hi
Externí odkaz:
https://doaj.org/article/dbc973f0316e425991c6bc0093bd4f9f
Autor:
Micah L. A. Heldeweg, Jorge E. Lopez Matta, Mark E. Haaksma, Jasper M. Smit, Carlos V. Elzo Kraemer, Harm-Jan de Grooth, Evert de Jonge, Lilian J. Meijboom, Leo M. A. Heunks, David J. van Westerloo, Pieter R. Tuinman
Publikováno v:
Intensive Care Medicine Experimental, Vol 9, Iss 1, Pp 1-13 (2021)
Abstract Background Lung ultrasound can adequately monitor disease severity in pneumonia and acute respiratory distress syndrome. We hypothesize lung ultrasound can adequately monitor COVID-19 pneumonia in critically ill patients. Methods Adult patie
Externí odkaz:
https://doaj.org/article/ebfc7678014f4655a3cbe489a8370c24
Autor:
Marloes van den Berg, Eva L. Peters, Robbert J. van der Pijl, Shengyi Shen, Leo M. A. Heunks, Henk L. Granzier, Coen A. C. Ottenheijm
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 15689 (2022)
Diaphragm weakness frequently develops in mechanically ventilated critically ill patients and is associated with increased morbidity, including ventilator weaning failure, mortality, and health care costs. The mechanisms underlying diaphragm weakness
Externí odkaz:
https://doaj.org/article/ef16f1dac81a40c68876286ad3172bfe
Autor:
Annemijn H. Jonkman, Tim Frenzel, Euan J. McCaughey, Angus J. McLachlan, Claire L. Boswell-Ruys, David W. Collins, Simon C. Gandevia, Armand R. J. Girbes, Oscar Hoiting, Matthijs Kox, Eline Oppersma, Marco Peters, Peter Pickkers, Lisanne H. Roesthuis, Jeroen Schouten, Zhong-Hua Shi, Peter H. Veltink, Heder J. de Vries, Cyndi Shannon Weickert, Carsten Wiedenbach, Yingrui Zhang, Pieter R. Tuinman, Angélique M. E. de Man, Jane E. Butler, Leo M. A. Heunks
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-11 (2020)
Abstract Background Expiratory muscle weakness leads to difficult ventilator weaning. Maintaining their activity with functional electrical stimulation (FES) may improve outcome. We studied feasibility of breath-synchronized expiratory population mus
Externí odkaz:
https://doaj.org/article/22b4c7d1ae37486b908d588cc18e78fe
Publikováno v:
Annals of Intensive Care, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract Background Critical illness has detrimental effects on the diaphragm, but the impact of critical illness on other major muscles of the respiratory pump has been largely neglected. This study aimed to determine the impact of critical illness
Externí odkaz:
https://doaj.org/article/f5d55f6bd37a4b21a8fd40166f72cf20
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-10 (2020)
Abstract This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2020. Other selected articles can be found online at https://www.biomedcentral.com/collections/annualupdate2020. Further information
Externí odkaz:
https://doaj.org/article/75db791c843b4ff0be115321ee64e27e
Autor:
Euan J. McCaughey, Annemijn H. Jonkman, Claire L. Boswell-Ruys, Rachel A. McBain, Elizabeth A. Bye, Anna L. Hudson, David W. Collins, Leo M. A. Heunks, Angus J. McLachlan, Simon C. Gandevia, Jane E. Butler
Publikováno v:
Critical Care, Vol 23, Iss 1, Pp 1-11 (2019)
Abstract Background For every day a person is dependent on mechanical ventilation, respiratory and cardiac complications increase, quality of life decreases and costs increase by > $USD 1500. Interventions that improve respiratory muscle function dur
Externí odkaz:
https://doaj.org/article/d835bcbc96034429aa579f37054b0b0e