Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Leo M Njongmeta"'
Autor:
Shehnaz Lokhandwala, Xin Fang, Suryakant D Waghela, Jocelyn Bray, Leo M Njongmeta, Andy Herring, Karim W Abdelsalam, Christopher Chase, Waithaka Mwangi
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170425 (2017)
Bovine viral diarrhea virus (BVDV) plays a key role in bovine respiratory disease complex, which can lead to pneumonia, diarrhea and death of calves. Current vaccines are not very effective due, in part, to immunosuppressive traits and failure to ind
Externí odkaz:
https://doaj.org/article/1d1a1e67b34f41b6b41739d045e0edf9
Autor:
Benjamin L Makepeace, Siv Aina Jensen, Sandra J Laney, Charles K Nfon, Leo M Njongmeta, Vincent N Tanya, Steven A Williams, Albert E Bianco, Alexander J Trees
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 3, Iss 11, p e544 (2009)
Human onchocerciasis, caused by the filarial nematode Onchocerca volvulus, is controlled almost exclusively by the drug ivermectin, which prevents pathology by targeting the microfilariae. However, this reliance on a single control tool has led to in
Externí odkaz:
https://doaj.org/article/a56ab19f058a4807acee37e0b137a6d0
Autor:
Christopher C. L. Chase, Shehnaz Lokhandwala, Suryakant D. Waghela, Andy D. Herring, Jocelyn Bray, Karim W. Abdelsalam, Waithaka Mwangi, Leo M. Njongmeta, Xin Fang
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 1, p e0170425 (2017)
PLoS ONE, Vol 12, Iss 1, p e0170425 (2017)
Bovine viral diarrhea virus (BVDV) plays a key role in bovine respiratory disease complex, which can lead to pneumonia, diarrhea and death of calves. Current vaccines are not very effective due, in part, to immunosuppressive traits and failure to ind
Autor:
Jocelyn Bray, Waithaka Mwangi, Nancy H. Ing, Suryakant D. Waghela, Chang-Hsin Chen, Daad Abi-Ghanem, Jackson L. McReynolds, Leo M. Njongmeta, Luc Berghman
Publikováno v:
Developmental & Comparative Immunology. 34:1139-1143
CD40 is mainly expressed by professional antigen-presenting cells (APCs). Its ligand, CD40L, is transiently expressed on activated CD4(+) T-cells. CD40-CD40L interactions mediate T-cell help to APCs and provide crucial signals for affinity maturation
Autor:
Matthew W. Ryan, Randall M. Goldblum, Elisabeth Shell, Alexander J. Indrikovs, Waithaka Mwangi, D. Mark Estes, Leo M. Njongmeta, Seckin O. Ulualp, Mark A. Endsley
Publikováno v:
The Journal of Immunology. 182:1854-1859
Over the last several years, there has been a great deal of progress in characterizing the role of dendritic cells (DCs) in the activation and modulation of B cells. DC-secreted chemokines can induce B cell trafficking to the lymph nodes. DC-produced
Autor:
Charles K. Nfon, Vincent N. Tanya, Alexander J. Trees, Leo M. Njongmeta, Benjamin L. Makepeace
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 76:67-72
Although vector control and ivermectin chemotherapy have led to a dramatic reduction in the incidence of river blindness (onchocerciasis), there is a consensus that additional control tools are required to sustain and extend this success. The recogni
Autor:
Charles K. Nfon, Ian M. Hastings, Jeffrey Gilbert, Benjamin L. Makepeace, Leo M. Njongmeta, Alfons Renz, Vincent N. Tanya, Kenneth Pfarr, Alexander J. Trees
Publikováno v:
The Journal of Infectious Diseases. 192:1483-1493
Development of a drug lethal to adult Onchocerca volvulus (i.e., macrofilaricide) is a research priority for the control of human onchocerciasis. Using bovine O. ochengi infections, we investigated the effects of oxytetracycline administered in a sho
Autor:
Benjamin L. Makepeace, Alexander J. Trees, Leo M. Njongmeta, Vincent N. Tanya, Charles K. Nfon, J. Gilbert
Publikováno v:
International Journal for Parasitology. 34:1069-1074
Ivermectin administration is now the major tool in the control of human onchocerciasis (caused by Onchocerca volvulus) based on its suppression of microfilariae and hence the prevention of disease. However, in Africa, transmission is not eliminated a
Autor:
Jesús Hernández, Lilian Flores-Mendoza, Carlos Velazquez, Waithaka Mwangi, Leo M. Njongmeta, Jocelyn Bray
Publikováno v:
Veterinary immunology and immunopathology. 146(1)
The aim of this work was to develop mAbs against porcine CD205 and to conduct a comparative analysis of the CD205 protein expression on lymphoid tissues, monocyte-derived dendritic cells (DCs) and DCs isolated from the porcine skin. To conduct this s
Autor:
Steven A. Williams, Leo M. Njongmeta, Siv Aina Jensen, Sandra J. Laney, Alexander J. Trees, Albert E. Bianco, Benjamin L. Makepeace, Charles K. Nfon, Vincent N. Tanya
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 3, Iss 11, p e544 (2009)
PLoS Neglected Tropical Diseases, Vol 3, Iss 11, p e544 (2009)
Human onchocerciasis, caused by the filarial nematode Onchocerca volvulus, is controlled almost exclusively by the drug ivermectin, which prevents pathology by targeting the microfilariae. However, this reliance on a single control tool has led to in