Zobrazeno 1 - 10
of 2 440
pro vyhledávání: '"Leo I"'
Autor:
Leo I. Dominguez, Terence L. Robinson
Publikováno v:
HortTechnology, Vol 34, Iss 6 (2024)
The success of a new high-density apple planting depends on how fast the grower can recoup the high investment that these systems require. The right balance between vegetative growth and cropping during the early life of the planting is where tree gr
Externí odkaz:
https://doaj.org/article/46f5ca46fde24d29a05e6a26fe1f2696
Autor:
Nilanjan Ghosh, Alison Sehgal, Fei Fei Liu, Ana Kostic, Alessandro Crotta, Marc De Benedetti, Jillian Faccone, Lily Peng, Leo I. Gordon
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
This study assessed the comparative efficacy of lisocabtagene maraleucel (liso-cel) in PILOT (NCT03483103), an open-label, phase II study, versus conventional second-line (2L) chemotherapy regimens in the real world administered to patients with rela
Externí odkaz:
https://doaj.org/article/674fa5856aea46528e6b18fe12b5a1e0
Autor:
Megan Melody, Leo I. Gordon
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Historically, management of relapsed or refractory (R/R) Diffuse large B-cell (DLBCL) following first-line chemoimmunotherapy has been second-line chemotherapy, followed by high-dose chemotherapy and consolidative autologous hematopoietic stem cell t
Externí odkaz:
https://doaj.org/article/4e0c311965b74081bff0bceebd73e913
Autor:
Narendranath Epperla, Lei Feng, Nirav N. Shah, Lindsey Fitzgerald, Harsh Shah, Deborah M. Stephens, Catherine J. Lee, Thomas Ollila, Geoffrey Shouse, Alexey V. Danilov, Kevin A. David, Pallawi Torka, Hamza Hashmi, Brian Hess, Stefan K. Barta, Jason T. Romancik, Jonathon B. Cohen, Kaitlin Annunzio, Adam S. Kittai, John Reneau, Joanna Zurko, Imran A. Nizamuddin, Jane N. Winter, Leo I. Gordon, Shuo Ma, Romil Patel, Loretta Nastoupil, Sairah Ahmed, Reem Karmali
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-7 (2023)
Abstract Chimeric antigen receptor T-cell therapy (CAR-T) has been successful in treating relapsed/refractory B-cell lymphomas. However, its role in the treatment of diseases involving the central nervous system (CNS) is not well studied. We performe
Externí odkaz:
https://doaj.org/article/c3e2fa17ee934883ab1d81fbb67a6b3b
Autor:
Reem Karmali, Frederique St‐Pierre, Shuo Ma, Kelly D. Foster, Jason Kaplan, Xinlei Mi, Barbara Pro, Jane N. Winter, Leo I. Gordon
Publikováno v:
eJHaem, Vol 4, Iss 1, Pp 108-114 (2023)
Abstract Background: TAK‐659, a novel oral SYK inhibitor, has demonstrated efficacy in heavily pretreated diffuse large B‐cell lymphoma (DLBCL). We report results of a phase I single‐institution escalation study of front‐line treatment with R
Externí odkaz:
https://doaj.org/article/4ddec0d795ad48768f1172140048cc49
Autor:
Leo I. Gordon, Fei Fei Liu, Julia Braverman, Daanish Hoda, Nilanjan Ghosh, Mehdi Hamadani, Gerhard C. Hildebrandt, Lily Peng, Shien Guo, Ling Shi, Alison Sehgal
Publikováno v:
Haematologica, Vol 109, Iss 3 (2023)
In the single-arm, open-label, multicenter, phase II PILOT study, second-line treatment with the chimeric antigen receptor (CAR) T-cell therapy lisocabtagene maraleucel (liso-cel) in patients with relapsed or refractory (R/R) large B-cell lymphoma (L
Externí odkaz:
https://doaj.org/article/f85d926987c6464784c910fa8b1e7fda
Autor:
Adam Yuh Lin, Leo I. Gordon
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 13 (2023)
The study of the cellular and molecular microenvironment in B cell lymphoma, especially diffuse large B cell lymphoma (DLBCL), has led to prognostic and therapeutic algorithms that may improve patient outcomes. Emerging gene signature panels provide
Externí odkaz:
https://doaj.org/article/0f96eed0eb5346f7abaa824e3400ef68
Publikováno v:
eJHaem, Vol 1, Iss 2, Pp 596-600 (2020)
Abstract Ibrutinib, a known Burton's tyrosine kinase (BTK) and interleukin‐2 inducible T‐cell kinase (ITK) inhibitor, is used for the treatment of B‐cell disorders (chronic lymphocytic leukemia [CLL] and various other lymphomas) and chronic gra
Externí odkaz:
https://doaj.org/article/464fc94fbbfd4931a8a7970c5c291347
Autor:
Leo I. Amodu, Asaph Levy, Crystal Kyaw, Darshan Padmanabhan, Alexandra Osman, Mukesh Tiwari, Jeffrey Nicastro, Gene Coppa, Ernesto Molmenti, Horacio L. Rodriguez Rilo
Publikováno v:
European Medical Journal, Vol 1, Iss 1, Pp 77-85 (2016)
Pancreatic cancer is the most common lethal cancer, with annual incidence and mortality rates being approximately equal. This dismal prognosis can be attributed to late diagnosis making the cancers unresectable. These cancers respond poorly to chemot
Externí odkaz:
https://doaj.org/article/223770b36e2849ff81674550a7fbb211
Publikováno v:
F1000Research, Vol 7 (2018)
Mantle cell lymphoma (MCL) is a B-cell non-Hodgkin lymphoma with historically poor long-term survival compared with other B-cell malignancies. Treatment strategies for this disease are variable and dependent on symptoms and patient fitness. Despite r
Externí odkaz:
https://doaj.org/article/b627672964e84f42800b13923d872ceb