Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Leo Deguzman"'
Autor:
Nancy Gillett, Wyne P. Lee, L. Steven Beck, Yvette Xu, Leo Deguzman, Tue Nguyen, Edward P. Amento
Publikováno v:
Journal of Bone and Mineral Research. 8:753-761
The temporal dynamics of bone repair in a skull defect in rabbits was examined to characterize the in vivo cellular events occurring following a single local application of recombinant human TGF-beta 1 (rhTGF-beta 1). Rabbits received vehicle or 0.4,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6889757613e266e8b51be1d07984ec0f
https://doi.org/10.1002/jbmr.5650080614
https://doi.org/10.1002/jbmr.5650080614
Autor:
Theresa L. Chen, Arthur J. Ammann, Lorrie A. McFatridge, Wyne P. Lee, Thomas B. Aufdemorte, L. Steven Beck, Leo Deguzman, Yvette Xu
Publikováno v:
Journal of Bone and Mineral Research. 6:961-968
A single application of recombinant human transforming growth factor beta 1 (rhTGF-beta 1) adjacent to cartilage was found to induce bone formation in rabbit ear full-thickness skin wounds. At doses that optimally promote soft tissue healing, 25-100
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da9ba5d93c3847fe8e022c5fa8b58e8a
https://doi.org/10.1002/jbmr.5650060910
https://doi.org/10.1002/jbmr.5650060910
Autor:
Leo Deguzman, Edward P. Amento, Nancy Gillett, Wyne P. Lee, Lorrie A. McFatridge, L. Steven Beck, Yvette Xu
Publikováno v:
Journal of Bone and Mineral Research. 6:1257-1265
Transforming growth factor beta 1 (TGF-beta 1) is a multifunctional regulatory protein. It is capable of inducing site-specific healing responses by increasing collagen synthesis and deposition as well as remodeling at sites of soft tissue repair. La
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::662ced0b7cfd4e61e2241c080b5e823b
https://doi.org/10.1002/jbmr.5650061117
https://doi.org/10.1002/jbmr.5650061117
Autor:
Stuart Bunting, Hope Steinmetz, Franklin Peale, John Street, Leo Deguzman, H. Paul Redmond, John Hoeffel, Jeffrey L. Cleland, Nicholas van Bruggen, Ann L. Daugherty, Min Bao, Napoleone Ferrara, Richard A.D. Carano, Ellen Filvaroff
Publikováno v:
Proceedings of the National Academy of Sciences. 99:9656-9661
Several growth factors are expressed in distinct temporal and spatial patterns during fracture repair. Of these, vascular endothelial growth factor, VEGF, is of particular interest because of its ability to induce neovascularization (angiogenesis). T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::936a449a086b6a48237aec17393b2203
https://doi.org/10.1073/pnas.152324099
https://doi.org/10.1073/pnas.152324099
Autor:
R. Smyth, M.T. Lipari, Dan L. Eaton, Canio J. Refino, Stuart Bunting, D. Schmitt, Surinder Jeet, Leo Deguzman
Publikováno v:
Fibrinolysis and Proteolysis. 14:305-314
To further evaluate the role of plasma carboxypeptidase B (pCPB) in modulating fibrinolysis, we investigated the effects of inhibiting pCPB on tissue plasminogen activator (tPA) induced lysis of preformed whole blood clots and on thrombus formation i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4529fd1611efa5b924088ba2c76eadb5
https://doi.org/10.1054/fipr.2000.0087
https://doi.org/10.1054/fipr.2000.0087
Autor:
Boonsri Ongpipattanakul, Wyne P. Lee, L. Steven Beck, Rita L. Wong, Tue H. Nguyen, Leo Deguzman
Publikováno v:
Journal of Pharmaceutical Sciences. 87:1379-1386
A 1.5 cm segmental defect in the radius of rabbits was used to compare healing at sites administered TGF-beta, with or without autologous bone marrow, to autogenous cortical bone graft. The carrier for TGF-beta consisted of tricalcium phosphate (TCP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85d71e156df2c2323880030158745e58
https://doi.org/10.1021/js9800883
https://doi.org/10.1021/js9800883
Autor:
Rita L. Wong, Wyne P. Lee, Zioncheck Tf, Tue H. Nguyen, Beck Ls, Osaka G, Leo Deguzman, Boonsri Ongpipattanakul
Publikováno v:
Journal of Biomedical Materials Research. 36:295-305
Tricalcium phosphate (TCP) was combined with amylopectin to form a deliverable carrier paste for recombinant human transforming growth factor β1 (rhTGF-β1) intended for bone repair applications. Approximately 80% of rhTGF-β1 was released from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d70271ce4d6834e765cd421a2394f032
https://doi.org/10.1002/(sici)1097-4636(19970905)36:3<295::aid-jbm4>3.0.co
https://doi.org/10.1002/(sici)1097-4636(19970905)36:3<295::aid-jbm4>3.0.co
Autor:
Austin L. Gurney, Zemin Zhang, Leo Deguzman, Kenneth J. Hillan, Franklin Peale, Phil Hass, Joe Kowalski, Lisa Dillard-Telm, Gilbert-Andre Keller, Jessica Foster, Linda Rangell, Gretchen Frantz, Napoleone Ferrara, Jennifer LeCouter
Publikováno v:
Obstetrical and Gynecological Survey. 57:32-34
The microvascular endothelium in endocrine glands is very permeable to circulating substances and secretory products, reflecting the need for rapid hormone release in response to homeostatic stimuli. Fenestrae, specialized discontinuities of the endo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c46d6372dd233df0834a649be788ea
https://doi.org/10.1097/00006254-200201000-00018
https://doi.org/10.1097/00006254-200201000-00018
Autor:
Theresa L. Chen, Leo Deguzman, L S Beck, Wyne P. Lee, Rebecca L. Bates, Arthur J. Ammann, L L McFatridge, Yvette Xu, Sue E. Hirabayashi
Publikováno v:
Growth Factors. 2:273-282
A dermal ulcer wound-healing model was established in rabbit ear to examine the effects of recombinant human transforming growth factor-beta 1 (rhTGF-beta 1) in wound healing. Histomorphometric examination of the wounds indicate a biphasic healing re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c76c9cab4ace06d9807b7c85ac292b
https://doi.org/10.3109/08977199009078015
https://doi.org/10.3109/08977199009078015
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 22(3)
10C12, a human antibody F(ab′) 2 , which specifically binds to the γ-carboxyglutamic acid domain of factor IX/factor IXa (F.IX/IXa), interferes with all known coagulation processes in which F.IX/IXa is involved. In a rabbit model of carotid artery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20383b5a87b9f6ee30064f724d4c015d
https://pubmed.ncbi.nlm.nih.gov/11884300
https://pubmed.ncbi.nlm.nih.gov/11884300