Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Leo D Wang"'
Autor:
Stephen J Forman, Massimo D’Apuzzo, Renate Starr, Christine E Brown, Brenda Aguilar, Michael E Barish, Behnam Badie, Leo D Wang, Darya Alizadeh, Jonathan C Hibbard, Marie Suzette Blanchard, Heini M Natri, Dongrui Wang, Julie R Ostberg, Jamie R Wagner, Jinny A Paul, Aleksandr Filippov, Ammar Chaudhry, Julie A Ressler, Julie Kilpatrick, Paige Myers-McNamara, Mike Chen, Russell C Rockne, Joseph Georges, Jana Portnow, Nicholas E Banovich
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/5d48eacb917c48b9aaf39b4f5f3d073d
Autor:
Hideho Okada, Lawrence Fong, Christine E Brown, Shilpa A Shahani, Paul R Walker, Meenal Sinha, Eric V Liu, Erin F Simonds, Edbert D Lu, Oscar Badillo, Shokoufeh Karimi, Whitney Tamaki, Chiara Rancan, Kira M Downey, Jacob Stultz, Lauren K McHenry, Nicole M Nasholm, Pavlina Chuntova, Anders Sundström, Vassilis Genoud, Leo D Wang, Fredrik J Swartling, William A Weiss, Mats Hellström
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Background Glioblastoma (GBM) is refractory to immune checkpoint inhibitor (ICI) therapy. We sought to determine to what extent this immune evasion is due to intrinsic properties of the tumor cells versus the specialized immune context of the brain,
Externí odkaz:
https://doaj.org/article/6b195c70cb3f48339806e87479adb50b
Autor:
Diana Gumber, Leo D. Wang
Publikováno v:
EBioMedicine, Vol 77, Iss , Pp 103941- (2022)
Summary: Chimeric antigen receptor (CAR) T cell therapy has emerged as a cancer treatment with enormous potential, demonstrating impressive antitumor activity in the treatment of hematological malignancies. However, CAR T cell exhaustion is a major l
Externí odkaz:
https://doaj.org/article/486ffb7968c94294ba9bfdfd7c0c4012
Autor:
Jasia Mahdi, Jorg Dietrich, Karin Straathof, Claire Roddie, Brian J. Scott, Tom Belle Davidson, Laura M. Prolo, Tracy T. Batchelor, Cynthia J. Campen, Kara L. Davis, Juliane Gust, Michael Lim, Robbie G. Majzner, Julie R. Park, Sonia Partap, Sneha Ramakrishna, Rebecca Richards, Liora Schultz, Nicholas A. Vitanza, Leo D. Wang, Crystal L. Mackall, Michelle Monje
Publikováno v:
Nature Medicine. 29:803-810
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::143fe1066eb3e5fc3eb3433c75c86c2f
https://doi.org/10.1038/s41591-023-02276-w
https://doi.org/10.1038/s41591-023-02276-w
Autor:
Renate Starr, Brenda Aguilar, Diana Gumber, Madeleine Maker, Stephanie Huard, Dongrui Wang, Wen-Chung Chang, Alfonso Brito, Vivian Chiu, Julie R. Ostberg, Benham Badie, Stephen J. Forman, Darya Alizadeh, Leo D. Wang, Christine E. Brown
Publikováno v:
Cancer Research Communications. 3:66-79
Chimeric antigen receptor (CAR) T cell immunotherapy is emerging as a powerful strategy for cancer therapy; however, an important safety consideration is the potential for off-tumor recognition of normal tissue. This is particularly important as liga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c22412355503ab8e71fb6b0bd799af2
https://doi.org/10.1158/2767-9764.crc-22-0185
https://doi.org/10.1158/2767-9764.crc-22-0185
Autor:
Erin E. Crotty, Ashley L. Wilson, Tom Davidson, Sophia Tahiri, Juliane Gust, Andrea M. Griesinger, Sujatha Venkataraman, Julie R. Park, Sabine Mueller, Brian R. Rood, Eugene I. Hwang, Leo D. Wang, Nicholas A. Vitanza
Publikováno v:
Current Oncology Reports.
Purpose of Review Correlative studies should leverage clinical trial frameworks to conduct biospecimen analyses that provide insight into the bioactivity of the intervention and facilitate iteration toward future trials that further improve patient o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a27c7c34c732d7465aa869488e5b1ad3
https://doi.org/10.1007/s11912-023-01423-3
https://doi.org/10.1007/s11912-023-01423-3
Autor:
Guido Marcucci, Ya-Huei Kuo, Nadia Carlesso, Stephen Forman, Leo D. Wang, Zheng Liu, Yate-Ching Yuan, Xiwei Wu, Davide Maestrini, Herman Wu, Ayelet Marom, Lianjun Zhang, Emily Carnahan, Guerry Cook, Wei-Kai Hua, Denis O'Meally, David E. Frankhouser, Jing Qi, Sergio Branciamore, Russell C. Rockne
Temporal dynamics of gene expression inform cellular and molecular perturbations associated with disease development and evolution. Given the complexity of high-dimensional temporal genomic data, an analytic framework guided by a robust theory is nee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9434819c6d2b6341baa87eb37c88ac11
https://doi.org/10.1158/0008-5472.c.6512287
https://doi.org/10.1158/0008-5472.c.6512287
Autor:
Guido Marcucci, Ya-Huei Kuo, Nadia Carlesso, Stephen Forman, Leo D. Wang, Zheng Liu, Yate-Ching Yuan, Xiwei Wu, Davide Maestrini, Herman Wu, Ayelet Marom, Lianjun Zhang, Emily Carnahan, Guerry Cook, Wei-Kai Hua, Denis O'Meally, David E. Frankhouser, Jing Qi, Sergio Branciamore, Russell C. Rockne
Table S1. Differentially expressed genes for c_1 vs c_1^* Table S2. Differentially expressed genes for c_2 vs c_1^* Table S3. Differentially expressed genes for c_3 vs c_1^* Table S4. Differentially expressed genes for c_2 vs c_1 Table S5. Differenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cac7593ac16783c4942fb5829245ed82
https://doi.org/10.1158/0008-5472.22426285.v1
https://doi.org/10.1158/0008-5472.22426285.v1
Autor:
Guido Marcucci, Ya-Huei Kuo, Nadia Carlesso, Stephen Forman, Leo D. Wang, Zheng Liu, Yate-Ching Yuan, Xiwei Wu, Davide Maestrini, Herman Wu, Ayelet Marom, Lianjun Zhang, Emily Carnahan, Guerry Cook, Wei-Kai Hua, Denis O'Meally, David E. Frankhouser, Jing Qi, Sergio Branciamore, Russell C. Rockne
Figure S1. Details of animal model and fusion gene CM, Figure S2. Ex vivo flow cytometry analysis of bone marrow, Figure S3. Details of principal component analysis, Figure S4. Comparison of state-space construction with different dimension reduction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e86b8148bcb011ba66d9887b73a42d
https://doi.org/10.1158/0008-5472.22426288.v1
https://doi.org/10.1158/0008-5472.22426288.v1
Autor:
Guido Marcucci, Ya-Huei Kuo, Nadia Carlesso, Stephen Forman, Leo D. Wang, Zheng Liu, Yate-Ching Yuan, Xiwei Wu, Davide Maestrini, Herman Wu, Ayelet Marom, Lianjun Zhang, Emily Carnahan, Guerry Cook, Wei-Kai Hua, Denis O'Meally, David E. Frankhouser, Jing Qi, Sergio Branciamore, Russell C. Rockne
In this supplement we provide additional data and methods to support our results. In particular, we show: details of our mouse model of AML; demonstrate the robustness of our state-space construction to normalization methods and gene selection criter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bcd275d8913253b4e0918e14ae2f0c5
https://doi.org/10.1158/0008-5472.22426282.v1
https://doi.org/10.1158/0008-5472.22426282.v1