Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Leo A. van der Pol"'
Publikováno v:
PLoS ONE, Vol 18, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/7905c94bab774f578fefafb87cc9534e
Autor:
Diego A. Suarez-Zuluaga, Leo A. van der Pol, Aart G. van 't Oever, Wilfried A.M. Bakker, Yvonne E. Thomassen
Publikováno v:
Vaccine: X, Vol 12, Iss , Pp 100223- (2022)
Inactivated polio vaccine production using attenuated Sabin strains (sIPV) instead of wild type polio viruses (cIPV) is an initiative encouraged by the World Health Organization. This use of attenuated viruses is preferred as it reduces risks related
Externí odkaz:
https://doaj.org/article/f78b177f25bb403c8e6badedb8244bf5
Autor:
Bas van de Waterbeemd, Gijsbert Zomer, Patricia Kaaijk, Nicole Ruiterkamp, René H Wijffels, Germie P J M van den Dobbelsteen, Leo A van der Pol
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e65157 (2013)
An improved detergent-free process has been developed to produce vaccine based on native outer membrane vesicles (NOMV) against Neisseria meningitidis serogroup B. Performance was evaluated with the NonaMen vaccine concept, which provides broad cover
Externí odkaz:
https://doaj.org/article/a7aca8616ff141fd93cc85f4a668c728
Autor:
Bas van de Waterbeemd, Gijsbert Zomer, Jan van den Ijssel, Lonneke van Keulen, Michel H Eppink, Peter van der Ley, Leo A van der Pol
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54314 (2013)
Outer membrane vesicles (OMV) contain immunogenic proteins and contribute to in vivo survival and virulence of bacterial pathogens. The first OMV vaccines successfully stopped Neisseria meningitidis serogroup B outbreaks but required detergent-extrac
Externí odkaz:
https://doaj.org/article/fef846d00b9043988082da0ff14b3826
Autor:
Yvonne E Thomassen, Aart G van 't Oever, Monique G C T van Oijen, René H Wijffels, Leo A van der Pol, Wilfried A M Bakker
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83374 (2013)
Worldwide efforts to eradicate polio caused a tipping point in polio vaccination strategies. A switch from the oral polio vaccine, which can cause circulating and virulent vaccine derived polioviruses, to inactivated polio vaccines (IPV) is scheduled
Externí odkaz:
https://doaj.org/article/0461923c79d044ae9607f98afe61c1a0
Autor:
Geert P M Mommen, Leo A. van der Pol, Bas van de Waterbeemd, Jeroen L. A. Pennings, Michel Weyts, Marieke Hoonakker, Arno van der Ark, Hugo D. Meiring, Betsy Kuipers, Joost P. Uittenbogaard, Arjen Sloots, Jan van den IJssel, Bernard Metz, Wichard Tilstra
Publikováno v:
Journal of Proteome Research. 16:528-537
Physicochemical and immunochemical assays were applied to substantiate the relation between upstream processing and the quality of whole-cell pertussis vaccines. Bordetella pertussis bacteria were cultured on a chemically defined medium using a conti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59b9fb62c1ddb241e25d94b86a225907
https://doi.org/10.1021/acs.jproteome.6b00668
https://doi.org/10.1021/acs.jproteome.6b00668
Publikováno v:
Biotechnology Journal
Outer membrane vesicles (OMVs) are released spontaneously during growth by many Gram‐negative bacteria. They present a range of surface antigens in a native conformation and have natural properties like immunogenicity, self‐adjuvation and uptake
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3592354a390e0400a737f08687c29929
http://europepmc.org/articles/PMC4768646
http://europepmc.org/articles/PMC4768646
Autor:
Dirk E. Martens, Michiel Stork, Matthias J.H. Gerritzen, Leo A. van der Pol, René H. Wijffels
Publikováno v:
Biotechnology Advances 35 (2017) 5
Biotechnology Advances
Biotechnology Advances, 35(5), 565-574
Biotechnology Advances
Biotechnology Advances, 35(5), 565-574
Outer membrane vesicles (OMVs) are naturally non-replicating, highly immunogenic spherical nanoparticles derived from Gram-negative bacteria. OMVs from pathogenic bacteria have been successfully used as vaccines against bacterial meningitis and sepsi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce68b1f2b29c4175f0aeaede0a5e464c
https://research.wur.nl/en/publications/bioengineering-bacterial-outer-membrane-vesicles-as-vaccine-platf
https://research.wur.nl/en/publications/bioengineering-bacterial-outer-membrane-vesicles-as-vaccine-platf
Publikováno v:
Pharmaceutical Bioprocessing. 2:207-210
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dbcc12d0dd2e2b59e282728fc62e47c
https://doi.org/10.4155/pbp.14.19
https://doi.org/10.4155/pbp.14.19
Publikováno v:
Vaccine. 32:3721-3724
Vaccination is the most effective prevention strategy to avoid influenza infection and for protection of large populations. The vast majority of influenza vaccines are still produced with allantoic fluid from fertilized chicken eggs. The presence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b2538001075ac66fd87f1ec79b01a6f
https://doi.org/10.1016/j.vaccine.2014.04.033
https://doi.org/10.1016/j.vaccine.2014.04.033