Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Leo A. Jakob"'
Autor:
Nora Tir, Lina Heistinger, Clemens Grünwald-Gruber, Leo A. Jakob, Stephan Dickgiesser, Nicolas Rasche, Diethard Mattanovich
Publikováno v:
Microbial Cell Factories, Vol 21, Iss 1, Pp 1-16 (2022)
Abstract Background Expansion of the genetic code is a frequently employed approach for the modification of recombinant protein properties. It involves reassignment of a codon to another, e.g., unnatural, amino acid and requires the action of a pair
Externí odkaz:
https://doaj.org/article/5a05cf744b974540bff7da90dfbf2737
The CASPON enzyme became an interesting enzyme for fusion protein processing because it generates an authentic N-terminus. However, the high cysteine content of the CASPON enzyme may induce aggregation via disulfide-bond formation, which can reduce e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9333fc7c515a54a5540a5e84911cda23
Autor:
Alois Jungbauer, Nico Lingg, Beate Beyer, Leo A. Jakob, Rupert Tscheließnig, Catarina Janeiro Ferreira
Publikováno v:
Journal of chromatography. A. 1649
Deploying two salts in hydrophobic interaction chromatography can significantly increase dynamic binding capacities. Nevertheless, the mechanistic understanding of this phenomenon is lacking. Here, we investigate whether surface tension or ionic stre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1930d9cdd5ca981633528121d792861
https://pubmed.ncbi.nlm.nih.gov/34038776
https://pubmed.ncbi.nlm.nih.gov/34038776
Publikováno v:
Separation and Purification Technology. 281:119985
Traditional chromatographic purification steps consist of long loading steps at a constant residence time, especially during early stages of the downstream process. The breakthrough behavior of the product is usually well defined. This information ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f647c1535361dc14dd9b1f37707b3545
https://doi.org/10.1016/j.seppur.2021.119985
https://doi.org/10.1016/j.seppur.2021.119985