Zobrazeno 1 - 10 of 69 pro vyhledávání: '"Leny Toma"'
1
Akademický článek
The Glypican proteoglycans show intrinsic interactions with Wnt-3a in human prostate cancer cells that are not always associated with cascade activation
Autor: Gabrielle Ferrante Alves de Moraes, Eduardo Listik, Giselle Zenker Justo, Carolina Meloni Vicente, Leny Toma
Publikováno v: BMC Molecular and Cell Biology, Vol 22, Iss 1, Pp 1-13 (2021)
Abstract Background Prostate cancer occurs through multiple steps until advanced metastasis. Signaling pathways studies can result in the identification of targets to interrupt cancer progression. Glypicans are cell surface proteoglycans linked to th
Externí odkaz: https://doaj.org/article/4bc15c34335248c6bc73d84c4b8324da
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2
Akademický článek
CASE SERIES OF PATIENTS UNDER BIWEEKLY TREATMENT WITH LARONIDASE: A REPORT OF A SINGLE CENTER EXPERIENCE
Autor: Sandra Obikawa Kyosen, Leny Toma, Helena Bonciani Nader, Marion Coting Braga, Vanessa Gonçalves Pereira, Sueli Canossa, João Bosco Pesquero, Vânia D’Almeida, Ana Maria Martins
Publikováno v: Revista Paulista de Pediatria, Iss 0 (2019)
ABSTRACT Objective: To report the stabilization of urinary glycosaminoglicans (GAG) excretion and clinical improvements in patients with mucopolysaccharidosis type I (MPS I) under an alternative dose regimen of laronidase of 1.2 mg/kg every other wee
Externí odkaz: https://doaj.org/article/38637534098d49dc82dca4878f97d736
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3
Supplementary Tables 1 - 2, Figures 1 - 2 from Enhanced Tumorigenic Potential of Colorectal Cancer Cells by Extracellular Sulfatases
Autor: Leny Toma, Helena B. Nader, Edwin A. Yates, Marcelo A. Lima, Carolina M. Vicente
Supplementary 1: Table 1 - Sequences of shRNA used in the study. Supplementary 2: Table 2 - Sequences of primers used in the study. Supplementary 3: mRNA level of SULFs after shRNA knockdown. Supplementary 4: mRNA expression of HS biosynthetic enzyme
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dae31fecdab87e7c1134fd666b4b86f6
https://doi.org/10.1158/1541-7786.22517478.v1
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5
Akademický článek
Heparan Sulfate Proteoglycans in Human Colorectal Cancer
Autor: Carolina Meloni Vicente, Daiana Aparecida da Silva, Priscila Veronica Sartorio, Tiago Donizetti Silva, Sarhan Sydney Saad, Helena Bonciani Nader, Nora Manoukian Forones, Leny Toma
Publikováno v: Analytical Cellular Pathology, Vol 2018 (2018)
Colorectal cancer is the third most common cancer worldwide, accounting for more than 610,000 mortalities every year. Prognosis of patients is highly dependent on the disease stage at diagnosis. Therefore, it is crucial to investigate molecules invol
Externí odkaz: https://doaj.org/article/af96bd0c3b1e4999be6420cb2181d9f3
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6
The Glypican proteoglycans show intrinsic interactions with Wnt-3a in human prostate cancer cells that are not always associated with cascade activation
Autor: Giselle Z. Justo, Leny Toma, Eduardo Listik, Carolina M. Vicente, Gabrielle Ferrante Alves de Moraes
Publikováno v: BMC Molecular and Cell Biology, Vol 22, Iss 1, Pp 1-13 (2021)
BMC Molecular and Cell Biology
Background Prostate cancer occurs through multiple steps until advanced metastasis. Signaling pathways studies can result in the identification of targets to interrupt cancer progression. Glypicans are cell surface proteoglycans linked to the membran
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d5da2206cb7d426e94285d6bfc2733d
https://doaj.org/article/4bc15c34335248c6bc73d84c4b8324da
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8
Glypican-1 in human glioblastoma: implications in tumorigenesis and chemotherapy
Autor: Eduardo Listik, Leny Toma
Publikováno v: Oncotarget
Glioblastoma is one of the most common malignant brain tumors, with which patients have a mean survival of 24 months. Glypican-1 has been previously shown to be overexpressed in human glioblastoma and to be negatively correlated with patient’s surv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59871efe99d035b9fbe2f072b3f1b06f
https://doi.org/10.18632/oncotarget.27492
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10
CASE SERIES OF PATIENTS UNDER BIWEEKLY TREATMENT WITH LARONIDASE: A REPORT OF A SINGLE CENTER EXPERIENCE
Autor: Helena B. Nader, Marion Coting Braga, Vânia D'Almeida, Sandra Obikawa Kyosen, João Bosco Pesquero, Ana Maria Martins, Leny Toma, Vanessa Gonçalves Pereira, Sueli Canossa
Publikováno v: Revista Paulista de Pediatria, Iss 0 (2019)
Revista Paulista de Pediatria v.37 n.3 2019
Revista Paulista de Pediatria (Ed. Português. Online)
Sociedade de Pediatria de São Paulo (SPSP)
instacron:SPSP
Revista Paulista de Pediatria
Objective: To report the stabilization of urinary glycosaminoglicans (GAG) excretion and clinical improvements in patients with mucopolysaccharidosis type I (MPS I) under an alternative dose regimen of laronidase of 1.2 mg/kg every other week. Method
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b8e7206b86e2bcd34e70a3c8c8e06b4
https://doi.org/10.1590/1984-0462/
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