Lens Regeneration: The Application of iSyTE and In Silico Approaches to Evaluate Gene Expression in Lens Organoids.

Autor: Shrestha SK; Department of Biological Sciences, University of Delaware, Newark, DE, USA., Lachke SA; Department of Biological Sciences, University of Delaware, Newark, DE, USA. salil@udel.edu.; Center for Bioinformatics & Computational Biology, University of Delaware, Newark, DE, USA. salil@udel.edu.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2025; Vol. 2848, pp. 37-58.

Spatial and morphologic features of lenses with different axial lengths in cataract patients: a swept-source optical coherence tomography-based study.

Autor: Chen C; Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China.; NHC Key Laboratory of Myopia and Related Eye Diseases; Key Laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai, 200031, China.; Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, 200031, China., Meng J; Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China.; NHC Key Laboratory of Myopia and Related Eye Diseases; Key Laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai, 200031, China.; Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, 200031, China., Cheng K; Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China.; NHC Key Laboratory of Myopia and Related Eye Diseases; Key Laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai, 200031, China.; Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, 200031, China., Kang C; Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China.; NHC Key Laboratory of Myopia and Related Eye Diseases; Key Laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai, 200031, China.; Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, 200031, China., Zhou L; Department of Ophthalmology, Fenghua Hospital of Traditional Chinese Medicine, Ningbo, 315500, Zhejiang, China. zhouliguang1982@163.com., Guo H; Department of Ophthalmology, Shanghai Heping Eye Hospital, Shanghai, 200437, China. guohaike@hotmail.com., Zhu X; Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China. zhuxiangjia1982@126.com.; NHC Key Laboratory of Myopia and Related Eye Diseases; Key Laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai, 200031, China. zhuxiangjia1982@126.com.; Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, 200031, China. zhuxiangjia1982@126.com.; State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, 200032, China. zhuxiangjia1982@126.com.

Publikováno v: BMC ophthalmology [BMC Ophthalmol] 2024 Dec 19; Vol. 24 (1), pp. 542. Date of Electronic Publication: 2024 Dec 19.

Ferroptosis is involved in the damage of ocular lens under long-term PM 2.5 exposure in rat models and humans.

Autor: Sheng F; Eye Center of the 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Key Lab of Ophthalmology, Hangzhou, Zhejiang, China., Gu Y; Eye Center of the 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Key Lab of Ophthalmology, Hangzhou, Zhejiang, China., Hao S; Eye Center of the 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Key Lab of Ophthalmology, Hangzhou, Zhejiang, China., Liu Y; Eye Center of the 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Key Lab of Ophthalmology, Hangzhou, Zhejiang, China., Chen S; Eye Center of the 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Key Lab of Ophthalmology, Hangzhou, Zhejiang, China., Lu B; Eye Center of the 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Key Lab of Ophthalmology, Hangzhou, Zhejiang, China., Chen L; Eye Center of the 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Key Lab of Ophthalmology, Hangzhou, Zhejiang, China., Zhao W; Eye Center of the 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Key Lab of Ophthalmology, Hangzhou, Zhejiang, China., Wu D; Eye Center of the 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Key Lab of Ophthalmology, Hangzhou, Zhejiang, China., Xu Y; Eye Center of the 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Key Lab of Ophthalmology, Hangzhou, Zhejiang, China., Chen R; Eye Center of the 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Key Lab of Ophthalmology, Hangzhou, Zhejiang, China., Han Y; Eye Center of the 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Key Lab of Ophthalmology, Hangzhou, Zhejiang, China., Lou X; Department of Environmental Health, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China., Wang X; Department of Environmental Health, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China., Chen Z; Department of Environmental Health, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China. Electronic address: zhjchen@cdc.zj.cn., Yao K; Eye Center of the 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Key Lab of Ophthalmology, Hangzhou, Zhejiang, China. Electronic address: xlren@zju.edu.cn., Fu Q; Eye Center of the 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Key Lab of Ophthalmology, Hangzhou, Zhejiang, China. Electronic address: 2313009@zju.edu.cn.

Publikováno v: Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2024 Dec; Vol. 288, pp. 117397. Date of Electronic Publication: 2024 Nov 28.

High ambient temperature may induce presbyopia via TRPV1 activation.

Autor: Nakazawa Y; Faculty of Pharmacy, Keio University, 1-5-30, Shibako-en, Minato-ku, Tokyo, 105-8512, Japan. nakazawa-ys@keio.jp., Kuno Y; Faculty of Pharmacy, Keio University, 1-5-30, Shibako-en, Minato-ku, Tokyo, 105-8512, Japan., Shimada H; Faculty of Pharmacy, Keio University, 1-5-30, Shibako-en, Minato-ku, Tokyo, 105-8512, Japan., Nagai N; Faculty of Pharmacy, Kindai University, Osaka, Japan., Hiramatsu N; Research Promotion and Support Headquarters, Fujita Health University, Toyoake, Japan., Takeda S; Department of Ophthalmology, Kanazawa Medical University, 1-1 Daigaku Uchinada-machi, Kahoku-gun, Ishikawa, 920-0293, Japan., Yamamoto N; Research Promotion and Support Headquarters, Fujita Health University, Toyoake, Japan., Funakoshi-Tago M; Faculty of Pharmacy, Keio University, 1-5-30, Shibako-en, Minato-ku, Tokyo, 105-8512, Japan., Sasaki H; Department of Ophthalmology, Kanazawa Medical University, 1-1 Daigaku Uchinada-machi, Kahoku-gun, Ishikawa, 920-0293, Japan. mogu@kanazawa-med.ac.jp.

Publikováno v: Medical molecular morphology [Med Mol Morphol] 2024 Dec; Vol. 57 (4), pp. 268-276. Date of Electronic Publication: 2024 Jul 09.

Disease-related non-muscle myosin IIA D1424N rod domain mutation, but not R702C motor domain mutation, disrupts mouse ocular lens fiber cell alignment and hexagonal packing.

Autor: Islam ST; Department of Biological Sciences, University of Delaware, Newark, Delaware, USA., Cheheltani S; Department of Biological Sciences, University of Delaware, Newark, Delaware, USA., Cheng C; School of Optometry and Vision Science Program, Indiana University, Bloomington, Indiana, USA.; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, California, USA., Fowler VM; Department of Biological Sciences, University of Delaware, Newark, Delaware, USA.; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, California, USA.

Publikováno v: Cytoskeleton (Hoboken, N.J.) [Cytoskeleton (Hoboken)] 2024 Dec; Vol. 81 (12), pp. 789-805. Date of Electronic Publication: 2024 Mar 22.