A kinesin‐based approach for inducing chromosome‐specific mis‐segregation in human cells.

Autor: Truong, My Anh, Cané‐Gasull, Paula, de Vries, Sippe G, Nijenhuis, Wilco, Wardenaar, René, Kapitein, Lukas C, Foijer, Floris, Lens, Susanne MA

Publikováno v: EMBO Journal; May2023, Vol. 42 Issue 10, p1-21, 21p

The chromosomal passenger complex and the spindle assembly checkpoint: kinetochore-microtubule error correction and beyond

Autor: Maia André F, Vader Gerben, Lens Susanne MA

Publikováno v: Cell Division, Vol 3, Iss 1, p 10 (2008)

Abstract During mitosis, correct bipolar chromosome attachment to the mitotic spindle is an essential prerequisite for the equal segregation of chromosomes. The spindle assembly checkpoint can prevent chromosome segregation as long as not all chromos

Externí odkaz: https://doaj.org/article/6b7b624f18c14a9a967b3031461f563e

Mechanistic basis for Sgo1-mediated centromere localization and function of the CPC

Autor: Maria Alba Abad, Tanmay Gupta, Michael A. Hadders, Amanda Meppelink, J. Pepijn Wopken, Elizabeth Blackburn, Juan Zou, Anjitha Gireesh, Lana Buzuk, David A. Kelly, Toni McHugh, Juri Rappsilber, Susanne M.A. Lens, A. Arockia Jeyaprakash

Publikováno v: Abad, M A, Gupta, T, Hadders, M A, Meppelink, A, Wopken, J P, Blackburn, E, Zou, J, Gireesh, A, Buzuk, L, Kelly, D A, Mchugh, T, Rappsilber, J, Lens, S M A & Jeyaprakash, A A 2022, ' Mechanistic basis for Sgo1-mediated centromere localization and function of the CPC ', Journal of Cell Biology, vol. 221, no. 8, e202108156 . https://doi.org/10.1083/jcb.202108156

Centromere association of the chromosomal passenger complex (CPC; Borealin-Survivin-INCENP-Aurora B) and Sgo1 is crucial for chromosome biorientation, a process essential for error-free chromosome segregation. Phosphorylated histone H3 Thr3 (H3T3ph;

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ae4c5c79dc9b650c4f811ebf002969
https://hdl.handle.net/20.500.11820/cf915011-2082-4fe9-9947-a47297790207