Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Lenore, Teichert"'
Autor:
Wolfgang Schmider, Bhaswati Mukherjee, Christoph Kapitza, Lenore Teichert, Irene Nowotny, Leszek Nosek
Publikováno v:
Diabetes, Obesity and Metabolism. 23:674-681
AIM To compare the pharmacokinetic exposure of SAR341402 Mix 70/30 (SARAsp -Mix) with US- and European (EU)-approved versions of insulin aspart Mix 70/30 (NovoLog Mix 70/30 [NN-Mix-US]/NovoMix 30 [NN-Mix-EU]) and SAR341402 insulin aspart solution (SA
Publikováno v:
Diabetes Technology & Therapeutics
Background: The objective of this study was to demonstrate the pharmacokinetic and pharmacodynamic similarity among SAR341402 insulin aspart biosimilar/follow-on product, United States-sourced insulin aspart (NovoLog®), and European Union-sourced in
Autor:
Christoph, Kapitza, Leszek, Nosek, Wolfgang, Schmider, Lenore, Teichert, Bhaswati, Mukherjee, Irene, Nowotny
Publikováno v:
Diabetes, Obesity & Metabolism
Aim To compare the pharmacokinetic exposure of SAR341402 Mix 70/30 (SARAsp‐Mix) with US‐ and European (EU)‐approved versions of insulin aspart Mix 70/30 (NovoLog Mix 70/30 [NN‐Mix‐US]/NovoMix 30 [NN‐Mix‐EU]) and SAR341402 insulin aspart
Autor:
Irina Velikyan, Veronique Tavernier, Olof Eriksson, Lars Johansson, Stefan Pierrou, Gunnar Antoni, Iina Laitinen, Michael Wagner, J. Tillner, Youssef Hijazi, Jan Erik Berglund, Lenore Teichert, Torsten Haack
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Unimolecular dual agonists for the glucagon-like peptide 1 receptor (GLP1R) and glucagon receptor (GCGR) are emerging as a potential new class of important therapeutics in type 2 diabetes (T2D). Reliable and quantitative assessments of in vivo occupa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a538fad419d890a7cbfab3a436036ef
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-424041
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-424041
Autor:
Lenore Teichert, Frank Wagner, Michael Wagner, Martin Bossart, Youssef Hijazi, Stefanie Keil, J. Tillner, Maximilian G. Posch, Torsten Haack, Philip J. Larsen, Christine Einig
Publikováno v:
Diabetes, Obesity and Metabolism. 21:120-128
AIMS To evaluate the safety, pharmacokinetics and pharmacodynamics of SAR425899, a novel polypeptide, active as an agonist at both the glucagon-like peptide-1 receptor (GLP-1R) and the glucagon receptor (GCR), in healthy volunteers and in overweight/
Publikováno v:
Drug Discovery and Evaluation: Methods in Clinical Pharmacology ISBN: 9783319566375
Drug Discovery and Evaluation: Methods in Clinical Pharmacology
Drug Discovery and Evaluation: Methods in Clinical Pharmacology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::740d46f08e30446b598edab27f6a0a3d
https://doi.org/10.1007/978-3-319-56637-5_5-1
https://doi.org/10.1007/978-3-319-56637-5_5-1
Publikováno v:
Diabetes, Obesity & Metabolism
Aims To characterize the variability in exposure and metabolic effect of insulin glargine 300 U/ml (Gla-300) at steady state in people with type 1 diabetes (T1DM). Methods A total of 50 participants with T1DM underwent two 24-h euglycaemic clamps in
Autor:
Nora Klöting, Anke Tönjes, Aimo Kannt, Matthias Blüher, Arne Dietrich, Lenore Teichert, Michael R. Schön, Anja Pfenninger
Publikováno v:
Diabetologia
Aims/hypothesis Nicotinamide-N-methyltransferase (NNMT) was recently shown to be upregulated in mouse models of insulin resistance and obesity. So far, it is unknown whether NNMT is regulated in human disease. We have explored the hypothesis that whi
Autor:
Lenore Teichert, Andreas Hirschfeld-Warneken, Heike Oberwittler, Reinhard Ding, Walter E. Haefeli, Roland Wesch, Hans Willerich, Karl-Heinz Lehr, Gerd Mikus
Publikováno v:
The Journal of Clinical Pharmacology. 47:70-77
HMR1766 is a new nitric oxide (NO)-independent activator of soluble guanylyl cyclase (sGC) in development for the treatment of cardiovascular diseases and chronic heart failure. A significant fraction of patients to be treated with HMR1766 is expecte