Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Lenny J. Negrón"'
Autor:
Lenny J. Negrón-Piñeiro, Yushi Wu, Sydney Popsuj, Diana S. José-Edwards, Alberto Stolfi, Anna Di Gregorio
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Tissue-specific gene expression is fundamental in development and evolution, and is mediated by transcription factors and by the cis-regulatory regions (enhancers) that they control. Transcription factors and their respective tissue-specific
Externí odkaz:
https://doaj.org/article/7a39e6e1259b4df080bcdb3810f6f83e
Gene expression in notochord and nuclei pulposi: a study of gene families across the chordate phylum
Autor:
Rahul Raghavan, Ugo Coppola, Yushi Wu, Chibuike Ihewulezi, Lenny J. Negrón-Piñeiro, Julie E. Maguire, Justin Hong, Matthew Cunningham, Han Jo Kim, Todd J. Albert, Abdullah M. Ali, Jean-Pierre Saint-Jeannet, Filomena Ristoratore, Chitra L. Dahia, Anna Di Gregorio
Publikováno v:
BMC Ecology and Evolution, Vol 23, Iss 1, Pp 1-22 (2023)
Abstract The transition from notochord to vertebral column is a crucial milestone in chordate evolution and in prenatal development of all vertebrates. As ossification of the vertebral bodies proceeds, involutions of residual notochord cells into the
Externí odkaz:
https://doaj.org/article/3d54d9e284bf4428a89a25051a747089
Autor:
Alessandro A. Bailetti, Lenny J. Negrón-Piñeiro, Vishal Dhruva, Sneh Harsh, Sean Lu, Aisha Bosula, Erika A. Bach
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 5 (2019)
Myeloproliferative neoplasms (MPNs) are clonal hematopoietic disorders that cause excessive production of myeloid cells. Most MPN patients have a point mutation in JAK2 (JAK2V617F), which encodes a dominant-active kinase that constitutively triggers
Externí odkaz:
https://doaj.org/article/6431b3b620cb4444a4b18048454a0da6
Autor:
Diana S José-Edwards, Arun Devotta, Yushi Wu, Jamie E Kugler, Lenny J Negrón-Piñeiro, Karina Braslavskaya, Jermyn Addy, Jean-Pierre Saint-Jeannet, Anna Di Gregorio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbe9f985de8b0421e7ed02dc21ea0e41
https://doi.org/10.7554/elife.73992.sa2
https://doi.org/10.7554/elife.73992.sa2
Autor:
Yushi Wu, Arun Devotta, Diana S José-Edwards, Jamie E Kugler, Lenny J Negrón-Piñeiro, Karina Braslavskaya, Jermyn Addy, Jean-Pierre Saint-Jeannet, Anna Di Gregorio
Publikováno v:
eLife
eLife, Vol 11 (2022)
eLife, Vol 11 (2022)
Gene regulatory networks coordinate the formation of organs and structures that compose the evolving body plans of different organisms. We are using a simple chordate model, the Ciona embryo, to investigate the essential gene regulatory network that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd610850a6c8d4147e4a10ad51a945c3
https://pubmed.ncbi.nlm.nih.gov/35049502
https://pubmed.ncbi.nlm.nih.gov/35049502
Publikováno v:
Genes
Genes, Vol 11, Iss 1262, p 1262 (2020)
Genes, Vol 11, Iss 1262, p 1262 (2020)
Tunicates are marine invertebrates whose tadpole-like larvae feature a highly simplified version of the chordate body plan. Similar to their distant vertebrate relatives, tunicate larvae develop a regionalized central nervous system and form distinct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc4a9537c001fd068044f258b7538a46
http://europepmc.org/articles/PMC7693978
http://europepmc.org/articles/PMC7693978
Autor:
Yamixa Delgado, Timothy B. Parks, Angel L. Vazquez-Maldonado, Lenny J. Negrón, Arthur D. Tinoco, Josué A. Benjamín-Rivera, Sergio A. Loza-Rosas, Charlene Munet-Colón, Alexandra M. Vázquez-Salgado, Kennett I. Rivero
Publikováno v:
Inorganic Chemistry. 56:7788-7802
The recent X-ray structure of titanium(IV)-bound human serum transferrin (STf) exhibiting citrate as a synergistic anion reveals a difference in Ti(IV) coordination versus iron(III), the metal endogenously delivered by the protein to cells. This find
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc8be488261bc9375018801d193c2ec8
https://doi.org/10.1021/acs.inorgchem.7b00542
https://doi.org/10.1021/acs.inorgchem.7b00542
Autor:
Sneh Harsh, Sean Lu, Vishal Dhruva, Lenny J. Negrón-Piñeiro, Aisha Bosula, Erika A. Bach, Alessandro A. Bailetti
Publikováno v:
Disease Models & Mechanisms.
Myeloproliferative neoplasms (MPNs) are clonal hematopoietic disorders that cause excessive production of myeloid cells. Most MPN patients have a point mutation in JAK2 (JAK2V617F), which encodes a dominant-active kinase that constitutively triggers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::307a417a2bc994919ee90b0ec82aa67d
https://doi.org/10.1242/dmm.038679
https://doi.org/10.1242/dmm.038679
Michael-type addition reactions are widely used to polymerize biocompatible hydrogels. The thiol-maleimide modality achieves the highest macromer coupling efficiency of the reported Michael-type pairs, but the resulting hydrogel networks are heteroge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f9e213b6ffaad317ba9ad8eec9d43ef
Autor:
Yushi Wu, Arun Devotta, Diana S José-Edwards, Jamie E Kugler, Lenny J Negrón-Piñeiro, Karina Braslavskaya, Jermyn Addy, Jean-Pierre Saint-Jeannet, Anna Di Gregorio
Publikováno v:
eLife, Vol 11 (2022)
Gene regulatory networks coordinate the formation of organs and structures that compose the evolving body plans of different organisms. We are using a simple chordate model, the Ciona embryo, to investigate the essential gene regulatory network that
Externí odkaz:
https://doaj.org/article/1ff7990aa16547bfb607968faf7ce345