Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Lennon H. McKendry"'
1
The synthesis of three isotopomers of 2-methyl-2-(4-[3-[1-(4-methylbenzyl)-5-oxo-4,5-dihydro-1H-[1,2,4]triazol-3-yl]propyl]phenoxy)propionic acid, a potent and selective peroxisome proliferator-activated receptor alpha agonist
Autor: Dean K. Clodfelter, Nagy A. Farid, Fengjiun Kuo, Lennon H. McKendry, William J. Wheeler
Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals. 50:693-701
Although fenofibrate (1a) is commercially available and clinically effective in lowering serum triglycerides, its activity and sub-type selectivity at the PPARα receptors are only moderate; therefore, there exists a need for more potent and sub-type
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4b4a85bd1a4c66f8118cbed5cc5906c8
https://doi.org/10.1002/jlcr.1395
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2
Anaerobic aquatic degradation of flumetsulam [N-(2,6-difluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide]
Autor: Jeffrey D. Wolt, Frederick R. Batzer, Michael A. Stanga, Jack R. Miller, Lennon H. McKendry, Julie D. Schwake, Debbie L. Holbrook, Stephen M. Brown, Gary A. Roth, David. Portwood
Publikováno v: Journal of Agricultural and Food Chemistry. 40:2302-2308
The herbicide flumetsulam [N-(2,6-difluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine-2-sul fonamide] was investigated in sediment-water systems to ascertain anaerobic aquatic degradation as a potential route for dissipation. In a strongly anaer
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::075b8a851afe724a97bf96d977af75ca
https://doi.org/10.1021/jf00023a050
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3
One step conversion of glutarimide-2,6-14C to pentachloropyridine-2,6-14C and its subsequent use in the synthesis of 2-octyl (4-amino-3,5-dichloro-6-fluoro-2-pyridinyloxy-2,6-14C)acetate
Autor: Lennon H. McKendry
Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals. 28:405-410
A convenient method of preparing 2-octyl (4-amino-3,5-dichloro-6-fluoro-2-pyridinyloxy-2,6-14C)acetate from glutarimide-2,6-14C is described. The process includes a novel one-step conversion of glutarimide-2,6-14C to pentachloropyridine-2,6-14C.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a6023642c78402893179addbf3b13cd6
https://doi.org/10.1002/jlcr.2580280406
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4
2, 6-dichloropyridine-2, 6-14C
Autor: W. W. Muelder, Lennon H. McKendry
Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals. 15:87-95
2, 6-Dichloropyridine-2, 6-14C with a specific activity of 18.79 mCi/mmole was prepared in a 78% yield via the reaction of glutarimide-2, 6-14C and PCl5. This represents a marked improvement over previously reported yields via this process.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d517e446bf390bbe63027c6c6812d76c
https://doi.org/10.1002/jlcr.2580150113
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5
3, 6-dichloropicolinic acid-2, 6- 14C
Autor: Lennon H. McKendry
Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals. 20:25-32
A 20.4 mCi sample of 99% radiochemically pure 3,6-dichloropicolinic acid-2,6-14C with a specific activity of 11.6 mCi/ mmole was synthesized via a five step process from glutarimide- 2, 6- 14C.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9100fde8326e2a0527fc10d81c56b560
https://doi.org/10.1002/jlcr.2580200105
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6
1-cyano-1-(6-phenoxy-2-pyridinyl-2, 6-14C)methyl 3-(2,2-dichloroethenyl)-2, 2-dimethyl-cyclopropanecarboxylate
Autor: Lennon H. McKendry
Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals. 21:401-408
A 15.7 mCi sample of 99% radiochemically pure 1-cyano-1-(6-phenoxy-2-pyridinyl-2,6-14C)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate with a specific activity of 21.3 mCi/mmole was prepared via a six step process from 2,6-dichloro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9aa3d344447efdf56180ec691abe96d5
https://doi.org/10.1002/jlcr.2580210503
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7
Preparation of 2-chloro-6-(2-furanylmethoxy)-4-trichloromethylpyridine-2,6-14C
Autor: Lennon H. McKendry
Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals. 22:517-523
A 16.7 mCi sample of 99+% radiochemically pure 2-chloro-6-(2-furanylmethoxy)-4-trichloromethylpyridine-2,6-14C with a specific activity of 13.2 mCi/mmole was prepared from trimethyl citrate-1,5-14C in a 44% yield via a three-step process.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d9c071b08a4328e8ee3d89fcbc6d8667
https://doi.org/10.1002/jlcr.2580220513
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8
A convenient synthesis of CIS/trans-3-chloroacrylic acid-UL-14C
Autor: G. A. Roth, Lennon H. McKendry
Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals. 25:1017-1019
A convenient method for oxidation of allylic alcohols to the corresponding carboxylic acids is described. A two phase (methylene chloride/aqueous) silver oxide oxidation circumvents isolation of the intermediate aldehydes, thus making the procedure w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e0705b8527e06775c745d096e7e0c255
https://doi.org/10.1002/jlcr.2580250914
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10
Akademický článek
3-(1,2-Diphenylethyl)-1,4,5,6-Tetrahydro-1,2,4-Triazine-3_14C Monohydrochloride.
Autor: McKendry, Lennon H.
Publikováno v: Journal of Labelled Compounds & Radiopharmaceuticals; Jan1980, Vol. 17 Issue 1, p43-51, 9p
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