Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Lennart T. Mars"'
Autor:
Florent Salvador, Laure Deramoudt, Frédéric Leprêtre, Martin Figeac, Thomas Guerrier, Julie Boucher, Mathilde Bas, Nathalie Journiac, Anneli Peters, Lennart T. Mars, Hélène Zéphir
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The key role of B cells in the pathophysiology of multiple sclerosis (MS) is supported by the presence of oligoclonal bands in the cerebrospinal fluid, by the association of meningeal ectopic B cell follicles with demyelination, axonal loss and reduc
Externí odkaz:
https://doaj.org/article/f338791c3ee54472908c2e437d606c40
Autor:
Florent Salvador, Laure Deramoudt, Frédéric Leprêtre, Martin Figeac, Thomas Guerrier, Julie Boucher, Mathilde Bas, Nathalie Journiac, Anneli Peters, Lennart T. Mars, Hélène Zéphir
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The key role of B cells in the pathophysiology of multiple sclerosis (MS) is supported by the presence of oligoclonal bands in the cerebrospinal fluid, by the association of meningeal ectopic B cell follicles with demyelination, axonal loss and reduc
Autor:
Céline Monnet, Alexandre Fontayne, Benjamin Beaufils, Emilie Jacque, Anais Engrand, Lennart T. Mars, Aurélie Dehenne, Christophe De Romeuf, Nathalie Fournier, Aurélie Terrier, Anne-Sophie Dezetter, Philippe Mondon, Mathilde Bas, Virginie Pochet-Beghin, Sylvie Jorieux, Cécile Beghin, Gilles Dupont
Publikováno v:
The Journal of Immunology. 202:1582-1594
The long serum t1/2 of IgGs is ensured by their interaction with the neonatal Fc receptor (FcRn), which salvages IgG from intracellular degradation. Fc glycosylation is thought not to influence FcRn binding and IgG longevity in vivo. In this article,
Autor:
Liliana E. Lucca, Jens Derbinski, Nicolas Fazilleau, Pierre Rufas, Abdulraouf Ramadan, Roland S. Liblau, Bruno Kyewski, Corine Perals, Lennart T. Mars, Pierre Paul Axisa, Meryem Aloulou
Publikováno v:
European Journal of Immunology
European Journal of Immunology, 2016, 46 (9), pp.2247-2259. ⟨10.1002/eji.201646416⟩
European Journal of Immunology, Wiley-VCH Verlag, 2016, 46 (9), pp.2247-2259. ⟨10.1002/eji.201646416⟩
European Journal of Immunology, 2016, 46 (9), pp.2247-2259. ⟨10.1002/eji.201646416⟩
European Journal of Immunology, Wiley-VCH Verlag, 2016, 46 (9), pp.2247-2259. ⟨10.1002/eji.201646416⟩
T-cell polyspecificity, predicting that individual T cells recognize a continuum of related ligands, implies that multiple antigens can tolerize T cells specific for a given self-antigen. We previously showed in C57BL/6 mice that part of the CD4(+) T
Autor:
Sylvie Guerder, Abdoulraouf Ramadan, Lennart T. Mars, Paul Menut, Karim Mahiddine, Laurent Serre, Maeva Girard, Nelly Rouquié, Bertrand Leobon, Liliana E. Lucca
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 199(11)
The genetic predisposition to multiple sclerosis (MS) is most strongly conveyed by MHC class II haplotypes, possibly by shaping the autoimmune CD4 T cell repertoire. Whether Ag-processing enzymes contribute to MS susceptibility by editing the peptide
Autor:
Lennart T. Mars, Jean-Charles Guéry, Abdulraouf Ramadan, Miriam Eisenstein, Roland S. Liblau, Liliana E. Lucca, Phuong Nguyen, Alessandro Sette, Nadège Carrié, Avraham Ben-Nun, Sabine Desbois, Terrence L. Geiger
Publikováno v:
The Journal of Immunology. 193:3267-3277
The recognition of multiple ligands by a single TCR is an intrinsic feature of T cell biology, with important consequences for physiological and pathological processes. Polyspecific T cells targeting distinct self-antigens have been identified in hea
Publikováno v:
The Journal of Immunology. 189:3140-3149
An increase in IL-17–producing CD8+ T (Tc17) cells has been reported in the peripheral blood of children with recent onset type 1 diabetes (T1D), but their contribution to disease pathogenesis is still unknown. To directly study the pathogenic pote
Publikováno v:
Current Opinion in Infectious Diseases. 25:312-320
Purpose of review The immune reconstitution inflammatory syndrome (IRIS) is an important clinical complication in HIV-infected patients initiating antiretroviral therapy. This review focuses on the latest literature pertaining to the pathogenesis of
Autor:
Ignacio Melero, Manuel Vilanova, Javier Hernandez, África González-Fernández, Cecilia Muñoz, Luis Graca, Luis Álvarez-Vallina, Pablo Ortiz, Lennart T. Mars
Publikováno v:
Inmunología. 30:128-134
Publikováno v:
FEBS Letters. 585:3758-3763
Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system leading to demyelination and axonal/neuronal loss. Cumulating evidence points to a key role for CD8 T cells in this disabling disease. Oligoclonal CD8 T cells reside