Aspergillus niger is a superior expression host for the production of bioactive fungal cyclodepsipeptides

Autor: Simon Boecker, Stefan Grätz, Dennis Kerwat, Lutz Adam, David Schirmer, Lennart Richter, Tabea Schütze, Daniel Petras, Roderich D. Süssmuth, Vera Meyer

Publikováno v: Fungal Biology and Biotechnology, Vol 5, Iss 1, Pp 1-14 (2018)

Abstract Background Fungal cyclodepsipeptides (CDPs) are non-ribosomally synthesized peptides produced by a variety of filamentous fungi and are of interest to the pharmaceutical industry due to their anticancer, antimicrobial and anthelmintic bioact

Externí odkaz: https://doaj.org/article/8cd91c4d21614971870fd01605d3ea4f

[Letter to the editor] Whole-genome amplification of sodium bisulfite–converted DNA can substantially impact quantitative methylation analysis using pyrosequencing

Autor: Jana Reins, Maximilian Mossner, Lennart Richter, Anke Kmetsch, Eckhard Thiel, Detlef Haase, Wolf-Karsten Hofmann

Publikováno v: BioTechniques, Vol 50, Iss 3, Pp 161-164 (2011)

Externí odkaz: https://doaj.org/article/c070961a23474d6eb831e6d536f4b09f

Mouse tissue distribution and persistence of the food-born fusariotoxins Enniatin B and Beauvericin

Autor: Daniela Heilos, Walter Berger, Michael Sulyok, Roderich D. Süssmuth, Petra Heffeter, Rita Dornetshuber-Fleiss, Yelko Rodríguez-Carrasco, Lukas Kenner, Lennart Richter

The fusariotoxins Enniatin B (Enn B) and Beauvericin (Bea) have recently aroused interest as food contaminants and as potential anticancer drugs. However, limited data are available about their toxic profile. Aim of this study was to investigate thei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bbfac262b033d1e2d28014c26dcd73f
https://europepmc.org/articles/PMC5850989/

The naturally born fusariotoxin enniatin B and sorafenib exert synergistic activity against cervical cancer in vitro and in vivo

Autor: Daniela Heilos, Roderich D. Süssmuth, Markus Zlesak, Rosa Lemmens-Gruber, Astrid Novicky, Rita Dornetshuber-Fleiss, Thomas Mohr, Walter Berger, Lennart Richter, Petra Heffeter

Publikováno v: Biochemical pharmacology. 93(3)

During the last decades substantial progress has been made in developing systemic cancer therapy. However, tumors are frequently intrinsically resistant against structurally and mechanistically unrelated drugs. Thus, it is of predominant interest to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::655c9f6e8b0ae506ce275eeadadea7c8
https://pubmed.ncbi.nlm.nih.gov/25557295

In vitro chemoenzymatic and in vivo biocatalytic syntheses of new beauvericin analogues

Autor: István Molnár, Jane Müller, Alexander Denisiuk, Lennart Richter, Sven C. Feifel, Patricia Espinosa-Artiles, Roderich D. Süssmuth, Diana Matthes, Yuquan Xu

Publikováno v: Matthes, D, Richter, L, Müller, J, Denisiuk, A, Feifel, S C, Xu, Y, Espinosa-Artiles, P, Süssmuth, R D & Molnár, I 2012, ' In vitro chemoenzymatic and in vivo biocatalytic syntheses of new beauvericin analogues ', Chemical Communications, vol. 48, no. 45, pp. 5674-5676 . https://doi.org/10.1039/c2cc31669b

Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbfbc71544c5e1a5c72a9d266632b6f9
http://depositonce.tu-berlin.de/handle/11303/5705